History and Objectives: Due to the prevalence of Berger disease and continuation of pain and its side effects among patients and probability of veinal-arterial fistula, the present study was carried out as a preliminary study on the effect of fistula on Berger patients referred to the Shohadaie Haft Tir hospital in 1998.

Materials and Methods: An experimental study on five patients suffering from Berger disease was performed. Pathologic findings were the basis of diagnosis of Berger disease. Veinal-arterial fistula was created on the ischemic and painful and its effect on the lowering of PVO2 ischemic organ and lowering of the pain were assessed. Results were examined with paired t-test and significant difference (P<0.0001) was observed.

Results: PVO2 before and after the operation was 44.4±6.28 and 69.6±4.2 respectively, with 25.2±3.11 and increase of 56.75% in arterial Oxygen pressure was obtained. Pain was decreased (Upto 75%) in all patients. Veinal-arterial fistula did not have any effect on prognosis and need of amputation in short run.

Conclusion: The results of the present study are very promising. Further study in a larger scale and maintenance of pain free organ for the patients is recommended.