1. Stafstrom CE, Carmant L. Seizures and epi‌le‌psy: an overview for neuroscientists. Cold Spring Harb Perspect Med 2015; 5(6).

2. Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, et al. Cyclooxygenase-2 in epilepsy. Epilepsia 2014; 55(1): 17-25.

3. Katyal J, Kumar H, Gupta YK. Anticonvulsant activity of the cyclooxygenase-2 (COX-2) inhibitor etoricoxib in pentylenetetrazole-kindled rats is asso‌ciated with memory impairment. Epilepsy Behav 2015; 44: 98-103.

4. Tanaka S, Nakamura T, Sumitani K, Takahashi F, Konishi R, Itano T, et al. Stage- and region-specific cyclooxygenase expression and effects of a selective COX-1 inhibitor in the mouse amygdala kindling model. Neurosci Res 2009; 65(1): 79-87.

5. Suemaru K, Yoshikawa M, Tanaka A, Araki H, Aso H, Watanabe M. Anticonvulsant effects of ace-taminophen in mice: Comparison with the effects of nonsteroidal anti-inflammatory drugs. Epilepsy Res 2018; 140: 22-28.

6. Salvadori MG, Banderó CR, Jesse AC, Gomes AT, Rambo LM, Bueno LM, et al. Prostaglandin E(2) potentiates methylmalonate-induced seizures. Epilepsia 2012; 53(1): 189-98.

7. Dhir A, Naidu PS, Kulkarni SK. Effect of cyclo‌oxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30 (8): 1478–85.

8. Oliveira MS, Furian AF, Royes LF, Fighera MR, Fiorenza NG, Castelli M, et al. Cyclo‌oxy‌ge‌nase-2/PGE2 pathway facilitates pentylene‌tetra‌zol-induced seizures. Epilepsy Res 2008; 79(1): 14–21.

9. Claycomb RJ, Hewett SJ, Hewett JA. Prophy‌lactic, prandial rofecoxib treatment lacks efficacy against acute PTZ-induced seizure generation and kindling acquisition. Epilepsia 2011; 52(2): 273–83.

10. Gobbo OL, O'Mara SM. Post-treatment, but not pre-treatment, with the selective cyclo‌oxy‌genase-2 inhibitor celecoxib markedly enhances fun‌ctional recovery from kainic acid-induced neurodegeneration. Neuroscience 2004; 125(2): 317–27.

11. Serrano GE, Lelutiu N, Rojas A, Cochi S, Shaw R, Makinson CD, et al. Ablation of cyclo‌oxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epile‌pticus. J Neurosci 2011; 31(42): 14850-60.

12. Chen C, Bazan NG. Endogenous PGE2 regu‌lates membrane excitability and synaptic trans‌mission in hippocampal CA1 pyramidal neurons. J Neurophysiol 2005; 93(2): 929-41.

13. Heydari A, Davoudi S. The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system. Seizure 2017; 45: 119-24.

14. Mesdaghinia A, Yazdanpanah H, Seddighi M, Banafshe HR, Heydari A. Effect of short-term lead exposure on PTZ-induced seizure threshold in mice. Toxicol Lett 2010; 199(1): 6-9.

15. Yang H, Chen C. Cyclooxygenase-2 in syn‌a‌ptic signaling. Curr Pharm Des 2008; 14 (14): 1443–51.

16. Marcheselli VL, Bazan NG. Sustained induc-tion of prostaglandin endoperoxide synthase-2by seizures in hippocampus. J Biol Chem 1996; 271 (40): 24794–9.

17. Desjardins P, Sauvageau A, Bouthillier A, Navarro D, Hazell AS, Rose C, et al. Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis. Neurochem Int 2003; 42 (4): 299-303.

18. Okada K. Yuhi T. Tsuji S. Yamashita U. Cyclo‌oxygenase-2 expression in the hippocampus of genetically epilepsy suscepti-ble El mice were increased after seizure. Brain Res 2001; 894 (2): 332-5.

19. Akarsu ES, Ozdayi S, Algan E, Ulupinar F. The neuronal excitability time-dependently changes fter lipopolysaccharide administration in mice: possible role of cyclooxygenase-2 induction. Epi‌lepsy Res 2006; 71(2-3): 181-7.

20. Ciceri P, Zhang Y, Shaffer AF, Leahy KM, Woerner MB, Smith WG, et al. Pharmacology of celecoxib in rat brain after kainate administration. J Pharmacol Exp Ther 2002; 302(3): 846-852.

21. Ueno N, Takegoshi Y, Kamei D, Kudo I. Murakami M. Coupling between cyclooxygenases and terminal prostanoid synthases. Biochem Biophys Res Commun 2005; 338(1): 70-6.

22. Rowley NM, Madsen KK, Schousboe A, Steve White H. Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control. Neurochem Int 2012; 61(4): 546-58.

23. Olsen RW. GABAA receptor: Positive and negativeallosteric modulators. Neuropharmacology 2018; S0028-3908(18): 30036-4.

24. Dhir A, Naidu PS, Kulkarni SK. Neuro‌protective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated bio‌chemical parameters in mice. Seizure 2007; 16(8): 691-7.

25. Liu B, Luo W, Zhang Y, Li H, Zhu N, Huang D, Zhou Y. Effect of celecoxib on cyclooxygenase-1-mediated prostacyclin synthesis and endothelium-dependent contraction in mouse arteries. Eur J Pharmacol 2013; 698(1-3): 354-61.

26. Sang N, Zhang J, Chen C. COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity. J Neurochem 2007; 102(6): 1966-77.

27. Andrade C, Singh NM, Thyagarajan S, Naga‌raja N, Sanjay Kumar Rao N, et al. Possible gluta‌matergic and lipid signalling mechanisms in ECT-induced retrograde amnesia: experimental evidence for involvement of COX-2, and review of literature. J Psychiatr Res 2008; 42(10): 837-50.