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Clinical Characteristics of Patent Ductus Arteriosus in Preterm Neonates and Associated Maternal-Neonatal Factors
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Yalda Taghipour    , Soodeh Hooshmandi * , Amin Janghorbani , Mohammad Soltani , Sajjad Rahimi |
| Department of Pediatrics, Faculty of Medicine, Semnan University of Medical Science, Semnan, Iran , s.Hooshmandi12@gmail.com |
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Abstract: (26 Views) |
Background and Objective:
Patent ductus arteriosus (PDA) is a common condition among preterm neonates and may be associated with significant complications. Despite numerous studies on congenital heart diseases, focused and population-based data regarding the prevalence of PDA in preterm infants remain limited in local settings. This study aimed to determine the prevalence of PDA and to evaluate its association with gestational age, neonatal sex, and maternal underlying conditions.
Methods
This retrospective cross-sectional study was conducted at a tertiary pediatric center in Semnan, Iran. Medical records of 1,490 preterm neonates admitted between 2019 and 2022 were reviewed. PDA diagnosis was confirmed based on documented echocardiographic findings. Data were analyzed using the chi-square test in SPSS version 26, and a p-value <0.05 was considered statistically significant.
Results
The prevalence of PDA among preterm neonates was 11.17%. A significant association was observed between lower gestational age and the occurrence of PDA (p=0.001), with 70.6% of affected neonates born at less than 35 weeks of gestation. A statistically significant relationship was also found between neonatal sex and PDA (p=0.000). No significant association was detected between maternal underlying diseases and PDA.
Conclusion
PDA has a considerable prevalence among preterm neonates and is associated with gestational age and neonatal sex. These findings provide context-specific epidemiological data and may serve as a foundation for future analytical and multicenter studies.
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| Keywords: Patent Ductus Arteriosus (PDA), Preterm Infants, Prevalence, Risk factors, Gestational age |
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Type of Study: Research |
Subject:
medicine, paraclinic
Received: 2026/01/5 | Revised: 2026/04/19 | Accepted: 2026/02/25
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