Abstract Background and Objective: Obesity has become a global epidemic and attention to its components and variables are very important to study. The present study was conducted by comparing the effectiveness of dialectical behavior therapy and mindfulness-based cognitive therapy on fear of negative evaluation in obese patients. Methods: In this study, a quasi-experimental pre-test-post-test-follow-up design with a control group was used. The statistical population included obese patients referring to Tehran medical centers in 2024. Using purposive sampling, 45 people were selected and randomly assigned to three groups (15 people): "Experiment 1 (recipients of dialectical behavior therapy)", "Experiment 2 (recipients of mindfulness-based cognitive therapy)" and "control". The research instrument included the Fear of Negative Evaluation Scale (BFNES). The data were analyzed using mixed variance analysis and Bonferroni post hoc test in SPSS-26 software. Results: Both dialectical behavior therapy and mindfulness-based cognitive therapy treatment packages significantly reduced fear of negative evaluation in the post-test and follow-up stages compared to the control group, and their effects were stable (p<0.001). In the variable of fear of negative evaluation, dialectical behavior therapy showed significantly greater effectiveness than mindfulness-based cognitive therapy (p<0.05). Conclusion: In general, both treatment packages were effective, but dialectical behavior therapy showed relative superiority in fear of negative evaluation. These findings can be used in designing psychological interventions for patients with obesity. Keywords: dialectical behavior therapy, mindfulness-based cognitive therapy, obesity, fear of negative evaluation.