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:: Volume 23, Issue 4 (Bimonthly 2019) ::
Feyz 2019, 23(4): 352-360 Back to browse issues page
Response of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase enzymes to aerobic exercise and royal jelly in multiple sclerosis patients
Sepideh Basirat-Dehkordi , Majid Vahidian-Rezazadeh * , Ali Moghtaderi
Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, I.R. Iran. , vahidian@ped.usb.ac.ir
Abstract:   (328 Views)
Background: Multiple Sclerosis (MS) is associated with many pathological changes and liver damage is one of the most important consequences. This study aimed to investigate the effect of aerobic exercise and the royal jelly on AST, ALT, and ALP enzymes in the patients with multiple sclerosis.
Materials and Methods: In this semi-experimental study, 42 MS patients were divided into 4 groups: 1-"Exercise +Royal Jelly" (n=10), 2-"Exercise +Placebo" (n=10), 3-"Royal Jelly" (n=11), 4-"Placebo" (n=11). The Exercise started with an ergometer at 60% HRmax for 6 weeks, 3 sessions per week then increased steadily in the sixth week to 80% HRmax. The daily dose of the royal jelly was 1000 mg. Plasma concentration of the liver enzymes was measured before and after the study.
Results: The levels of AST, ALT, and ALP enzymes were significantly reduced compared to the pre-test in the groups of the "Exercise+Royal Jelly" and "Exercise+Placebo" (P<0.05). Also, the ALT enzyme showed a significant decrease in the "Royal Jelly" group. The results of the statistical analysis indicated a significant reduction of the enzymes in the "Exercise+Royal Jelly" and the "Exercise + Placebo" groups compared to the "control" and the "Royal Jelly" groups at the end of the sixth week (P<0.05).
Conclusion: It seems that the aerobic exercise and the royal jelly consumption together had the most decreasing effect on serum levels of the liver enzymes in the multiple sclerosis patients, and It has a positive effect on the hepatic enzymes and especially the levels of ALT enzymes in patients.
Keywords: Aerobic exercise, Royal Jelly, Aspartate eminotransferase, Alanine eminotransferase, Alkaline phosphatase, Multiple sclerosis
Full-Text [PDF 282 kb]   (19 Downloads)    
Type of Study: Research | Subject: General
Received: 2019/03/13 | Accepted: 2019/06/3 | Published: 2019/09/30
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Basirat-Dehkordi S, Vahidian-Rezazadeh M, Moghtaderi A. Response of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase enzymes to aerobic exercise and royal jelly in multiple sclerosis patients. Feyz. 2019; 23 (4) :352-360
URL: http://feyz.kaums.ac.ir/article-1-3841-en.html


Volume 23, Issue 4 (Bimonthly 2019) Back to browse issues page
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