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Response of Aspartate Aminotransferase, Alanine Aminotransferase and Alkaline Phosphatase Enzymes Multiple Sclerosis Patients to Aerobic Exercise and Royal Jelly
Sepideh Basirat Dehkordi , Majid Vahidian-Rezazadeh * , Ali Moghtaderi
University of Sistan and Baluchestan , vahidian@ped.usb.ac.ir
Abstract:   (53 Views)
Background: Multiple sclerosis is associated with many pathological changes, and liver damage is one of the most important consequences. The purpose of this study was to investigate the effect of aerobic exercise and royal jelly on AST, ALT and ALP enzymes in patients with multiple sclerosis.
Materials and Methods: In this semi-experimental study, 42 MS patients were divided into 4 groups: 1-"Exercise +Royal Jelly" (n=10), 2-"Exercise +Placebo" (n=10), 3-"Royal Jelly" (n=10), 4-"Placebo" (n=11). The Exercise started with an ergometer at 60% HR max for6 weeks, 3 sessions per week. It then increased steadily in the sixth week to 80% HR max. The daily dose of royal jelly was1000 mg. Plasma concentration of liver enzymes was measured before and after the study.
Results: The levels of AST, ALT, and ALP enzymes were significantly reduced compared to the pre-test in the groups of "Exercise +Royal Jelly" and "Exercise +Placebo" (P<0.05). Also, the ALT enzyme showed a significant decrease in the "Royal Jelly" group. The results of the statistical analysis indicated a significant reduction of these enzymes in the "Exercise +Royal Jelly" and "Exercise + Placebo" groups compared to the "control" and "Royal Jelly" groups at the end of the sixth week (P<0.05).
Conclusion: The results of this study showed that aerobic exercise and royal jelly consumption had the most decreasing effect on serum levels of liver enzymes multiple sclerosis patients, and It has a positive effect on the hepatic enzymes and especially the levels of ALT enzymes in patients.
Keywords: Aerobic Exercise, Royal Jelly, Aspartate Aminotransferase, Alanine Aminotransferase, Alkaline Phosphatase, Multiple Sclerosis
     
Type of Study: Research | Subject: General
Received: 2019/03/13 | Accepted: 2019/06/3
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