Background: During the last decade, advances in the analytical methods have greatly increased our understanding of the role of trace elements in the human body. Minerals were categorized into macro and micronutrients, but it has become clear that trace elements such as copper and zinc can be as unique as vitamins in the human body.

Materials and Methods: An animal model was used for clinical studies. A diet containing inorganic copper was considered for the animals.

Results: Recently Brewer provided an understanding of the role of ingestion of inorganic copper on cognitive loss and its possible contributions to Alzheimer’s disease (AD). Similarly, Rosanna Squitti reviewed studies that indicate that the copper dysfunction may be a causative factor in the pathology of AD. Prasad' studies also revealed that zinc was not considered essential for the human body until 1963, but now it is believed that Zinc deficiency affects nearly 2 billion people around the world.

Conclusion: Zinc is a growth factor for the human and its deficiency resulting in growth retardation, gonadal failure, and premature death in children. Also, the copper in drinking water and copper supplements are a major factor triggering the AD epidemics. Therefore, people can reduce their risk of AD by stopping the use of copper supplements and testing the copper levels in their drinking water.