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:: دوره 27، شماره 4 - ( دوماه نامه 1402 ) ::
جلد 27 شماره 4 صفحات 472-461 برگشت به فهرست نسخه ها
تأثیر فعالیت ورزشی حاد و مزمن بر GDF-15 گردش خونی: مروری نظام مند و فراتحلیل
موسی خلفی ، امیر قنبرپور نصرتی ، راضیه سادات مصطفوی ، فاطمه حسینی جبلی
گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران ، mousa.khalafi@kashanu.ac.ir
چکیده:   (827 مشاهده)
زمینه و هدف: فاکتور تمایز رشد 15 (GDF15) سایتوکینی با اثرات ضدالتهابی می‌باشد که آثار فعالیت ورزشی حاد و مزمن بر آن به وضوح مشخص نیست. ازاین‌رو، هدف فراتحلیل حاضر تعیین تأثیر فعالیت ورزشی حاد و مزمن بر GDF15 گردش خونی می‌باشد.
روش‌ها: برای استخراج مقالات اصیل چاپ شده در مجلات فارسی و انگلیسی زبان، جستجوی جامع در پایگاه‌های اطلاعاتی PubMed، Web of Science، Scopus، مگیران، نورمگز و SID تا تاریخ 22 دسامبر 2022 صورت گرفت. دو فراتحلیل مجزا برای محاسبه اندازه اثر تفاوت میانگین استاندارد شده (SMD) و فاصله اطمینان 95 درصد برای اثر حاد و مزمن فعالیت ورزشی بر GDF15 انجام شد.
یافته‌ها: در مجموع 18 مطالعه شامل 551 آزمودنی وارد فراتحلیل شدند. نتایج نشان داد فعالیت ورزشی حاد منجر به افزایش معنی‌دار GDF15 می‌شود [001/0P=، (65/1 الی 80/0CI: ) 23/1]. درحالی‌که فعالیت ورزشی مزمن اثر معنی‌داری بر GDF15 نداشت [24/0P=، (96/0 الی 24/0-CI: ) 35/0].
نتیجه‌گیری: فعالیت ورزشی منجر به افزایش گذرا و کوتاه‌مدت GDF15 می‌شود که ممکن است در اثرات متابولیکی مفید فعالیت ورزشی مشارکت داشته باشد.
واژه‌های کلیدی: فعالیت ورزشی، GDF15، سایتوکاین
متن کامل [PDF 608 kb]   (493 دریافت)    
نوع مطالعه: مروري | موضوع مقاله: عمومى
دریافت: 1402/5/11 | ویرایش نهایی: 1402/8/8 | پذیرش: 1402/6/26 | انتشار: 1402/8/1
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Khalafi M, Ghanbarpour Nosrati A, Mostafavi R S, Hosseini Jebeli F. The effect of acute and chronic exercise on circulating GDF-15: a systematic review and meta-analysis. Feyz 2023; 27 (4) :461-472
URL: http://feyz.kaums.ac.ir/article-1-4934-fa.html

خلفی موسی، قنبرپور نصرتی امیر، مصطفوی راضیه سادات، حسینی جبلی فاطمه. تأثیر فعالیت ورزشی حاد و مزمن بر GDF-15 گردش خونی: مروری نظام مند و فراتحلیل. مجله علوم پزشکی فيض. 1402; 27 (4) :461-472

URL: http://feyz.kaums.ac.ir/article-1-4934-fa.html



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دوره 27، شماره 4 - ( دوماه نامه 1402 ) برگشت به فهرست نسخه ها
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