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:: Volume 11, Issue 1 (Quarterly 2007) ::
Feyz 2007, 11(1): 45-50 Back to browse issues page
Frequency rate of active hepatitis G virus infection among human immunodeficiency virus infected patients in Tehran
Ali Akbar Pourfathollah , Mostafa Haji-Molla-Hoseini , Soheila Soheili , Minoo Mohraz , Sadighe Amini , Mahnaz Aghaiepour , Shahram Samiee
, Pourfa@modares.ac.i
Abstract:   (8832 Views)

Background : Hepatitis virus infections are common in patients suffering from human immunodeficiency virus (HIV) infection due to similar transmission routes of these viruses. Hepatitis virus infections lead to impaired survival in HIV positive patients. In contrast to the expectations, some studies indicate that HGV infection slows down the progression and eventually death of AIDS patients. The aim of this study was to estimate the frequency of active HGV infection among HIV infected patients in Tehran.

Material and Methods: Flow cytometric analysis of lymphocyte subpopulations was performed on blood samples of 103 patients with HIV infection referring to the central laboratory of Iranian blood transfusion organization. Their plasma samples were analyzed for the presence of HGV RNA by RT-PCR. HGV Positive cases were confirmed by PCR-ELISA.

Results: Of 103 HIV-positive patients, 16 (15.5%) were HGV RNA-positive. It was apparent that the frequency of HGV in patients with CD4 count above 500 cell/μl is higher.

Conclusion: Sucha frequency is not high compared with those found in other studies. The high frequency of active HGV infection in patients with asymptomatic HIV infection may be due to the loss of active HGV infection in patients with advanced HIV infection.

Keywords: HGV, HIV and coinfection
Full-Text [PDF 209 kb]   (2000 Downloads)    
Type of Study: Research | Subject: General
Received: 2008/10/27 | Published: 2007/04/15
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Pourfathollah A A, Haji-Molla-Hoseini M, Soheili S, Mohraz M, Amini S, Aghaiepour M et al . Frequency rate of active hepatitis G virus infection among human immunodeficiency virus infected patients in Tehran. Feyz 2007; 11 (1) :45-50
URL: http://feyz.kaums.ac.ir/article-1-61-en.html


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This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
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Volume 11, Issue 1 (Quarterly 2007) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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