[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
AI::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 22, Issue 3 (Bimonthly 2018) ::
Feyz Med Sci J 2018, 22(3): 302-308 Back to browse issues page
The effect of honey consumption on lipid profiles in healthy individuals: A randomized clinical trial
Hamid Rasad , Mohammad Entezari , Behzad Mahaki , Maryam Nurany , Naseh Pahlavani *
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R. Iran. , PahlavaniN951@mums.ac.ir
Abstract:   (4626 Views)
Background: It has been indicated in several studies that honey consumption has beneficial effects on risk factors for cardiovascular disease. This study aimed at examining the effect of honey intake compared with sucrose on lipid profiles in young healthy people.
Materials and Methods: This randomized, single-blinded, clinical trial was performed on 60 healthy subjects with the age range of 18 to 30 years. Subjects were randomly divided into honey and sucrose groups. The honey group received 70 g honey per day and sucrose group received 70 g sucrose per day for one month. Lipid profiles of the participants were measured using the enzyme kit and compared in both groups (honey and sucrose) at the beginning and at the end of the intervention.
Results:  Results showed that there was no significant difference in the mean of the baseline FBS, SBP, and DBP between the honey and sucrose groups (P>0.3). From baseline to four weeks, honey reduced the levels of total cholesterol, TG, and LDL but sucrose intake increased these levels (P<0.3). Also, honey consumption increased HDL but sucrose intake decreased it (P<0.001). We adjusted confounding variables including age, physical activity and some nutrient intakes in all of these analyses.
Conclusion: Honey consumption, unlike sucrose, can decrease total cholesterol, TG, and LDL and also can increase HDL in healthy people.
Background: It has been indicated in several studies that honey consumption has beneficial effects on risk factors for cardiovascular disease. This study aimed at examining the effect of honey intake compared with sucrose on lipid profiles in young healthy people.
Materials and Methods: This randomized, single-blinded, clinical trial was performed on 60 healthy subjects with the age range of 18 to 30 years. Subjects were randomly divided into honey and sucrose groups. The honey group received 70 g honey per day and sucrose group received 70 g sucrose per day for one month. Lipid profiles of the participants were measured using the enzyme kit and compared in both groups (honey and sucrose) at the beginning and at the end of the intervention.
Results:  Results showed that there was no significant difference in the mean of the baseline FBS, SBP, and DBP between the honey and sucrose groups (P>0.3). From baseline to four weeks, honey reduced the levels of total cholesterol, TG, and LDL but sucrose intake increased these levels (P<0.3). Also, honey consumption increased HDL but sucrose intake decreased it (P<0.001). We adjusted confounding variables including age, physical activity and some nutrient intakes in all of these analyses.
Conclusion: Honey consumption, unlike sucrose, can decrease total cholesterol, TG, and LDL and also can increase HDL in healthy people.
Keywords: Honey, Sucrose, Total Cholesterol, Triacylglycerol, High-density lipoprotein, Low-density lipoprotein
Full-Text [PDF 227 kb]   (1392 Downloads)    
Type of Study: Applicable | Subject: medicine, paraclinic
Received: 2017/12/10 | Revised: 2018/08/8 | Accepted: 2018/06/17 | Published: 2018/08/4
References
1. Ghorpade AG, Shrivastava SR, Kar SS, Sarkar S, Majgi SM, Roy G. Estimation of the cardio‌vascular risk using World Health Organi‌za‌tion‌/International Society of Hypertension (WHO/ISH) risk prediction charts in a rural population of South India. IJHPM 2015;4(8):531.
2. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al. Kidney disease as a risk factor for development of cardiovascular disease. Circ 2003; 108(17): 2154-69.
3. Pahlavani N, Jafari M, Sadeghi O, Rezaei M, Rasad H, Rahdar HA, et al. L-arginine supplement‌ation and risk factors of cardiovascular diseases in healthy men: a double-blind randomized clinical trial. F1000Res 2014;3:306.
4. Kazemi T, Rezvani MR, Sharifzadeh GR, Sadri A, Moghaddam M, Reza H, et al. The prevalence of traditional cardiovascular risk factors in low socio‌economic use individuals in Birjand 2008 (East IRAN). JCTM 2015; 3(1): 263-9.
5. Moyer VA. Menopausal hormone therapy for the primary prevention of chronic conditions: US Preventive Services Task Force recommendation statement. Ann Intern Med 2013; 158(1): 47-54.
6. von Känel R. Psychosocial stress and cardio‌vascular risk: current opinion. Swiss Med Wkly 2012; 142: w13502
7. Eckel RH, Jakicic JM, Ard JD, De Jesus JM, Miller NH, Hubbard VS, et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardio‌vascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63(25 Part B): 2960-84.
8. Al-Waili NS. Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. J Med Food 2004; 7(1): 100-7.
9. Yaghoobi N, Al-Waili N, Ghayour-Mobarhan M, M R Parizadeh S, Abasalti Z, Yaghoobi Z, et al. Natural Honey and Cardiovascular Risk Factors; Effects on Blood Glucose, Cholesterol, Triacylgly‌cerole, CRP, and Body Weight Compared with Sucrose TSWJ 2008; 463-9 p.
10. Bahrami M, Ataie-Jafari A, Hosseini S, Foruzanfar MH, Rahmani M, Pajouhi M. Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial. Int J Food Sci Nutr 2009; 60(7): 618-26.
11. Münstedt K, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. Effect of honey on serum cholesterol and lipid values. J Med Food 2009; 12(3): 624-8.
12. Bhatti I, Inayat S, Uzair B, Menaa F, Bakhsh S, Khan H, et al. Effects of Nigella sativa (Kalonji) and Honey on Lipid Profile of Hyper lipidemic Smokers. IJPER 2016; 50(3): 376-84.
13. Bekkaye I, Azzoug S, Dahmoun K, Chentli F. Effects of natural honey intake on glycaemic con‌trol and lipid profile in type 2 diabetes. JNSD 2016; 2(1).
14. Al-Waili NS. Intravenous and intrapulmonary administration of honey solution to healthy sheep: effects on blood sugar, renal and liver function tests, bone marrow function, lipid profile, and carbon tetrachloride-induced liver injury. J Med Food 2003; 6(3): 231-47.
15. Erejuwa OO, Nwobodo NN, Akpan JL, Okorie UA, Ezeonu CT, Ezeokpo BC, et al. Nigerian honey ameliorates hyperglycemia and dyslipidemia in alloxan-induced diabetic rats. Nutrients 2016; 8(3): 95.
16. Mushtaq R, Mushtaq R, Khan ZT. Effects of natural honey on lipid profile and body weight in normal weight and obese adults: a randomized clinical trial. PJZ 2011; 43(1): 161-9.
17. Vasheghani-Farahani A, Tahmasbi M, Asheri H, Ashraf H, Nedjat S, Kordi R. The Persian, last 7-day, long form of the International Physical Activity Questionnaire: translation and validation study. Asian J Sports Med 2011; 2(2): 106 -16.
18. Townsend N, Nichols M, Scarborough P, Rayner M. Cardiovascular disease in Europe—epidemiological update 2015. Eur Heart J 2015; 36(40): 2696-705.
19. O’Donovan G, Lee IM, Hamer M, Stamatakis E. Association of “weekend warrior” and other leisure time physical activity patterns with risks for all-cause, cardiovascular disease, and cancer mort‌al‌ity. JAMA Int Med 2017; 177(3): 335-42.
20. Alagwu EA, Okwara JE, Nneli RO, Osim EE. Effect of honey intake on serum cholesterol, triglycerides and lipoprotein levels in albino rats and potential benefits on risks of coronary heart disease. Niger J Physiol Sci 2011; 26(2): 161-5.
21. Schramm DD, Karim M, Schrader HR, Holt RR, Cardetti M, Keen CL. Honey with high levels of antioxidants can provide protection to healthy human subjects. J Agric Food Chem 2003; 51(6): 1732-5.
22. Majid M, Younis MA, Naveed AK, Shah MU, Azeem Z, Tirmizi SH. Effects of natural honey on blood glucose and lipid profile in young healthy Pakistani males. J Ayub Med Coll Abbottabad 2013; 25(3-4): 44-7.
23. Sousa JM, de Souza EL, Marques G, Meireles B, de Magalhães Cordeiro ÂT, Gullón B, et al. Polyphenolic profile and antioxidant and antibacterial activities of monofloral honeys produced by Meliponini in the Brazilian semiarid region. Food Res Int J 2016; 84: 61-8.
24. Ebbert JO, Jensen MD. Fat depots, free fatty acids, and dyslipidemia. Nutrients 2013; 5(2): 498-508.
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rasad H, Entezari M, Mahaki B, Nurany M, Pahlavani N. The effect of honey consumption on lipid profiles in healthy individuals: A randomized clinical trial. Feyz Med Sci J 2018; 22 (3) :302-308
URL: http://feyz.kaums.ac.ir/article-1-3490-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 22, Issue 3 (Bimonthly 2018) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.05 seconds with 46 queries by YEKTAWEB 4710