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:: Volume 20, Issue 2 (Bimonthly 2016) ::
Feyz 2016, 20(2): 173-179 Back to browse issues page
Association between clinical symptoms and laboratory findings in the diagnosis of Candida vaginitis
Fatemeh Nozhat * , Mandana Zarei
Department of Biology, Payame Noor University (PNU), I. R. Iran. , f_nozhat@pnu.ac.ir
Abstract:   (3781 Views)

Background: Vulvovaginal candidiasis is the second most common vaginal infection among women. In this study, the association between clinical symptoms and laboratory findings in diagnosis of Candida vaginitis has been investigated.

Materials and Methods: This descriptive analytical study was carried out on women (n=220) with vaginitis symptoms. After diagnosing the Candida vaginitis based on the clinical symptoms (e.g. white color cheesy discharges, erythema or edema of the vulva and the vagina), two samples were taken from vaginal discharge for each participant. The first sample was cultured on Sabouraud dextrose agar medium in sterile conditions. Another sample was transferred directly to slide, on which a drop of the KOH (10٪) solution was added. The samples were immediately transferred to the laboratory for microscopic examination. The results were compared to clinical findings and analyzed by Chi-square and McNemar’s tests using SPSS software. P<0.05 was considered as the significant level.

Results: One-hundred twenty four (56.4%), 64 (29.1%) and 78 (35.5%) out of 220 participants referred with vaginal complains were identified as vaginal candida infection in their physical examination, direct smear examination  and culture on Sabouraud dextrose agar, respectively.

Conclusion: The mere apparent assessment of the clinical symptoms and patients complaints may be misleading the   diagnosis and treatment of the disease.

Keywords: Vulvovaginal Candidiasis, Candida albicans, Clinical symptoms, Female Genitalia
Full-Text [PDF 270 kb]   (2089 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2016/06/16 | Revised: 2017/08/1 | Accepted: 2016/06/16 | Published: 2016/06/16
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Nozhat F, Zarei M. Association between clinical symptoms and laboratory findings in the diagnosis of Candida vaginitis. Feyz 2016; 20 (2) :173-179
URL: http://feyz.kaums.ac.ir/article-1-3030-en.html

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Volume 20, Issue 2 (Bimonthly 2016) Back to browse issues page
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