Background: Diabetic patients need to detect blood glucose level (BGL) foe diagnosis, treatment and flow up. Typically a blood sample for analysis is obtained via intravenous or a finger stick or other such invasive procedures. Often, this procedure cause physical and mental stress to the patient. Thus, it is desirable to use other biologic liquid such as saliva to detect the blood glucose level. The present study attempts to determine the correlation coefficient between blood glucose level and saliva glucose level (SGL) in healthy men.

Materials and Methods: It was a cross sectional study. 130 blood and 130 saliva samples were gathered from 10 healthy men in 13 times during a five-day period. Each day samples were taken 3 times, fasting, post parricidal and evening. Samples were analyzed with glucose oxidase method.

Results: Mean of fasting blood glucose level was 84.9±3.43 mg/dl (58-118 mg/dl). Mean of saliva glucose level was 1.22±0.81 mg/dl (0.32-4.94 mg/dl). Correlation coefficient between BGC and SGL from the 5 days of measurement was 0.23. Correlation coefficient for each day was 0.38 (First day), 0.29 (Second day), 0.01 (Third day) and 0.37 (Fourth day).

Conclusion: Unfortunately with this correlation coefficient and limited range of SGL we can not use saliva to detect BGL.