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:: Volume 29, Issue 5 (Bimothly 2025) ::
Feyz Med Sci J 2025, 29(5): 434-435 Back to browse issues page
Exercise and autoimmune diseases: From contraindication to prescription- An emerging therapeutic paradigm
Mojtaba Sajadian , Solmaz Sadat Hosseini Zijoud *
Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran , hosseini1920@gmail.com
Abstract:   (202 Views)
Editorial
Keywords: Exercise, Autoimmune Diseases, Physical activity
Full-Text [PDF 217 kb]   (32 Downloads)    
Type of Study: Editorial | Subject: medicine, paraclinic
Received: 2025/10/14 | Revised: 2025/11/4 | Accepted: 2025/10/21 | Published: 2025/11/3
References
1. Luo B, Xiang D, Ji X, Chen X, Li R, Zhang S, et al. The anti-inflammatory effects of exercise on autoimmune diseases: A 20-year systematic review. J Sport Health Sci. 2024; 13: 353-67. doi.10.1016/j.jshs.2024.02.002 PMID: 38336299 PMCID: PMC11127262
2. Souza P, Gonçalves E, Pedroso G, Farias H, Junqueira S, Marcon R, et al. Physical Exercise Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Peripheral Immune Response and Blood-Brain Barrier Disruption. Mol Neurobiol. 2017; 54:4723-37. doi.10.1007/s12035-016-0014-0 PMID: 27535668
3. Einstein O, Fainstein N, Touloumi O, Lagoudaki R, Hanya E, Grigoriadis N, et al. Exercise training attenuates experimental autoimmune encephalomyelitis by peripheral immunomodulation rather than direct neuroprotection. Experimental Neurol. 2018; 299: 56-64. doi.10.1016/j.expneurol.2017.10.008 PMID: 29042241
4. Zong B, Yu FY, Zhang X, Zhao W, Li S, Li L. Mechanisms underlying the beneficial effects of physical exercise on multiple sclerosis: focus on immune cells. Front Immunol. 2023; 14. doi.10.3389/fimmu.2023.1260663 PMID: 37744366 PMCID: PMC10512009
5. Rizzo F, Guadalupi L, Sanna K, Vanni V, Fresegna D, Vito F, et al. Exercise protects from hippocampal inflammation and neurodegeneration in experimental autoimmune encephalomyelitis. Brain, Behavior, and Immunity. 2021; 98:13-27.doi.10.1016/j.bbi.2021.08.212 PMID: 34418562
6. da Luz Scheffer D, Latini A. Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2020;1866(10):165823. doi: 10.1016/j.bbadis.2020.165823 PMid:32360589 PMCid:PMC7188661
7. Birnbaum S, Porcher R, Portero P, Clair B, Demeret S, Eymard B, et al. Home-based exercise in autoimmune myasthenia gravis: A randomized controlled trial. Neuromuscular Disord. 2021;31:726-35. doi.10.1016/j.nmd.2021.05.002 PMID: 34266752
8. Sieczkowska S, Smaira F, Mazzolani B, Gualano B, Roschel H, Peçanha T. Efficacy of home-based physical activity interventions in patients with autoimmune rheumatic diseases: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism. 2021; 513: 576-87. doi.10.1016/j.semarthrit.2021.04.004 PMID: 33992809
9. Xie YC, Li Z, Wang Y, Xue X, Wenhai, Zhang Y, et al. Effects of moderate- versus high- intensity swimming training on inflammatory and CD4+ T cell subset profiles in experimental autoimmune encephalomyelitis mice. J Neuroimmunol. 2019; 328: 60-7. doi.10.1016/j.jneuroim.2018.12.005 PMID: 30583215
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Sajadian M, Hosseini Zijoud S S. Exercise and autoimmune diseases: From contraindication to prescription- An emerging therapeutic paradigm. Feyz Med Sci J 2025; 29 (5) :434-435
URL: http://feyz.kaums.ac.ir/article-1-5417-en.html


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Volume 29, Issue 5 (Bimothly 2025) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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