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:: Volume 24, Issue 3 (Bimonthly 2020) ::
Feyz 2020, 24(3): 322-331 Back to browse issues page
Impact of Aerobic and Combined Exercise Training on Serum Levels of Fetuin-A and Some Metabolic Syndrome Indices of Overweight and Obese Women: A clinical trial study
Alieh Shahraki , Majid Vahidian-Rezazadeh * , Morteza Nikoofar
Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, I.R.Iran. , vahidian@ped.usb.ac.ir
Abstract:   (226 Views)
Background: This study aimed to investigate the effect of endurance and combination training on serum levels of Fetuin-A and metabolic syndrome of overweight and obese women.
Materials and Methods: This was a semi-experimental study and 45 overweight and obese women were randomly divided into three groups: “control”, “aerobic exercise” and “combined exercise” groups. The aerobic exercise and combined exercise groups were active for eight weeks. After blood sampling, Fetuin-A, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride, total cholesterol and glucose were measured.
Results: The results showed that after eight weeks in the aerobic and combined groups, Fetuin-A significantly increased (P=0.022, P=0.011). Also, LDL was significantly decreased in aerobic and combined groups (P=0.006, P=0.024). The results showed that the combined group had a significant decrease in TC, TG, FAT, BMI, and WHR compared to baseline and a significant increase in HDL (P<0.05). Also, Fetuin-A decreased in aerobic and combined groups compared to the control group. The combined group showed a significant decrease in TC compared to the control and aerobic groups (P<0.05). Besides, the combined group had lower TG, FAT, BMI, and WHR indices compared to the control group (P<0.05).
Conclusion: The results of this study showed that combined exercises compared aerobic training had significant decreasing effects on Fetuin-A, as well as metabolic syndrome indices in obese and overweight individuals and contributes to the improvement of the dangers of obesity and cardiovascular risk factors.
Keywords: Aerobic exercise, Combined exercise, Fetuin-A, Metabolic syndrome
Full-Text [PDF 309 kb]   (28 Downloads)    
Type of Study: Research | Subject: General
Received: 2019/09/27 | Accepted: 2020/07/4 | Published: 2020/08/19
References
1. Karam BS, Chavez-Moreno A, Koh W, Akar JG, Akar FG. Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes. Cardiovasc Diabetol 2017; 16(1): 120.
2. Stefan N, Häring HU. The role of hepatokines in metabolism. Nat Rev Endocrinol 2013; 9(3): 144.
3. Jung TW, Yoo HJ, Choi KM. Implication of hepatokines in metabolic disorders and cardiovascular diseases. BBA Clin 2016; 5: 108-13.
4. Aroner SA, Mukamal KJ, St-Jules DE, Budoff MJ, Katz R, Criqui MH, et al. Fetuin-A and risk of diabetes independent of liver fat content: the multi-ethnic study of atherosclerosis. Am J Epidemiol 2017; 185(1): 54-64.
5. Zhang LY, Liu T, Teng YQ, Yao XY, Zhao TT, Lin LY, et al. Effect of a 12-week aerobic exercise training on serum fetuin-A and adipocytokine levels in type 2 diabetes. Exp Clin Endocrinol Diabetes 2018; 126(08): 487-92.
6. Brix JM, Stingl H, Hollerl F, Schernthaner GH, Kopp HP, Schernthaner G. Elevated Fetuin-A concentrations in morbid obesity decrease after dramatic weight loss. J Clin Endocrinol Metab 2010; 95(11): 4877-81.
7. Stefan N, Fritsche A, Weikert C, Boeing H, Joost HG, Häring HU, et al. Plasma fetuin-A levels and the risk of type 2 diabetes. Diabetes 2008; 57(10): 2762-7.
8. Sun Q, Cornelis MC, Manson JE, Hu FB. Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the US. Diabetes 2013; 62(1): 49-55.
9. O'Leary VB, Jorett AE, Marchetti CM, Gonzalez F, Phillips SA, Ciaraldi TP, et al. Enhanced adiponectin multimer ratio and skeletal muscle adiponectin receptor expression following exercise training and diet in older insulin-resistant adults. Am J Physiol Endocrinol Metab 2007; 293(1): E421-7.
10. Fisher E, Stefan N, Saar K, Drogan D, Schulze MB, Fritsche A, et al. Association of AHSG gene polymorphisms with fetuin-A plasma levels and cardiovascular diseases in the EPIC-Potsdam study. Circ Cardiovasc Genet 2009; 2(6): 607-13.
11. Denecke B, Gräber S, Schäfer C, Heiss A, Wöltje M, Jahnen-Dechent W. Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A. Biochem J 2003; 376(1): 135-45.
12. Afshar R, Shegarfy L, Shavandi N, Sanavi S. Effects of aerobic exercise and resistance training on lipid profiles and inflammation status in patients on maintenance hemodialysis. Indian J Nephrol 2010; 20(4): 185.
13. Tune JD, Goodwill AG, Sassoon DJ, Mather KJ. Cardiovascular consequences of metabolic syndrome. Translational Res 2017; 183: 57-70.
14. Kang DW, Lee J, Suh SH, Ligibel J, Courneya KS, Jeon JY. Effects of exercise on insulin, IGF axis, adipocytokines, and inflammatory markers in breast cancer survivors: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev 2017; 26(3): 355-65.
15. Xu A. Chronic exercise alleviates obesity-related metabolic dysfunction by enhancing FGF21 sensitivity in adipose tissues. Diabetes Res Clin Pract 2016; 120: S24.
16. Polak J, Klimcakova E, Moro C, Viguerie N, Berlan M, Hejnova J, et al. Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor α in obese women. Metabolism 2006; 55(10): 1375-81.
17. Brouwers B, Hesselink MK, Schrauwen P, Schrauwen-Hinderling VB. Effects of exercise training on intrahepatic lipid content in humans. Diabetologia 2016; 59(10): 2068-79.
18. Sardar MA, Gaeini A, Ramezani JA. The effect of 8-weeks of regular physical activity on blood glucose, body mass index, maximal oxygen uptake (Vo2max) and risk factors cardiovascular diseases in patients with type of 1 diabetes mellitus. IJEM 2008; 10(2): 91-7. [in Persian]
19. Blumenthal JB, Gitterman A, Ryan AS, Prior SJ. Effects of exercise training and weight loss on plasma Fetuin-a levels and insulin sensitivity in overweight older men. J Diabetes Res 2017, Article ID 1492581, 7 pages, 2017. https://doi.org/10.1155/2017/1492581.
20. Malin SK, Mulya A, Fealy CE, Haus JM, Pagadala MR, Scelsi AR, et al. Fetuin-A is linked to improved glucose tolerance after short-term exercise training in nonalcoholic fatty liver disease. J Appl Physiol 2013; 115(7): 988-94.
21. Reinehr T, Roth CL. Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss. J Clin Endocrinol Metab 2008; 93(11): 4479-85.
22. Schultes B, Frick J, Ernst B, Stefan N, Fritsche A. The effect of 6-weeks of aerobic exercise training on serum fetuin-A levels in non-diabetic obese women. Exp Clin Endocrinol Diabetes 2010; 118(10): 754-6.
23. Jackson AS, Pollock ML, Ward AN. Generalized equations for predicting body density of women. Med Sci Sports Exerc 1980; 12(3): 175-81.
24. Jahantigh A, Delavar R, Mogharnasi M. The Effect of Eight Weeks of Combined Training and Garlic Supplementation On Adiponectin And Lipid Changes Among Inactive Boys. Armaghan-e-Danesh 2017; 22(1): 18-31. [in Persian]
25. Ramírez-Vélez R, García-Hermoso A, Hackney AC, Izquierdo M. Effects of exercise training on Fetuin-a in obese, type 2 diabetes and cardiovascular disease in adults and elderly: a systematic review and Meta-analysis. Lipids Health Dis 2019; 18(1): 23.
26. Fakhrpour R, Ebrahim K, Ahmadizad S, Tayebi Khosroshahi H. Effects of combination training on Fetuin A, C-Reactive protein and some biochemical parameters in hemodialysis patients. Sport Physiol 2017; 8(32): 115-30. [in Persian]
27. Kraemer WJ, Fleck SJ, Deschenes MR. Exercise physiology: integrating theory and application. Lippincott Williams & Wilkins; 2011 Mar 1.214-21.
28. Zhang X, Devlin HM, Smith B, Imperatore G, Thomas W, Lobelo F, et al. Effect of lifestyle interventions on cardiovascular risk factors among adults without impaired glucose tolerance or diabetes: A systematic review and meta-analysis. PloS One 2017; 12(5): e0176436.
29. Lira FS, Yamashita AS, Uchida MC, Zanchi NE, Gualano B, Martins E, et al. Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile. Diabetol Metab Syndr 2010; 2(1): 31.
30. Shaw IN, Shaw BS, Krasilshchlkov OL. Comparison of aerobic and combined aerobic and resistance training on low-density lipoprotein cholesterol concentrations in men. Cardiovasc J Afr 2009; 20(5): 290.
31. Yang SJ, Hong HC, Choi HY, Yoo HJ, Cho GJ, Hwang TG, et al. Effects of a three‐month combined exercise programme on fibroblast growth factor 21 and fetuin‐A levels and arterial stiffness in obese women. Clin Endocrinol (Oxf) 2011; 75(4): 464-9.
32. Bey L, Hamilton MT. Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low‐intensity activity. J Physiol 2003; 551(2): 673-82.
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Shahraki A, Vahidian-Rezazadeh M, Nikoofar M. Impact of Aerobic and Combined Exercise Training on Serum Levels of Fetuin-A and Some Metabolic Syndrome Indices of Overweight and Obese Women: A clinical trial study. Feyz. 2020; 24 (3) :322-331
URL: http://feyz.kaums.ac.ir/article-1-3981-en.html


Volume 24, Issue 3 (Bimonthly 2020) Back to browse issues page
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