:: Volume 16, Issue 4 (Bimonthly 2012) ::
Feyz 2012, 16(4): 337-345 Back to browse issues page
Correlation between working memory and quality of life in multiple sclerosis patients
Negin Chehreh-Negar, Farnosh Shams *, Sareh Zarshenas, Alireza Nikseresht
Shiraz University of Medical Sciences , sh_00_f@yahoo.com
Abstract:   (6178 Views)

Background: Working memory impairment is one of the most important cognitive deficits in multiple sclerosis (MS) patients that affect the quality of life even in the early stages of the disease. The purpose of this study was to evaluate the correlation between the working memory and the quality of life in MS patients.

Materials and Methods: This case-control study was performed on 35 (case) and 28 healthy (control) participants. Working memory and quality of life were assessed using Wechsler adult intelligence scale and the MS quality of life 54 (MSQOL-54) inventory, respectively.

Results: Results showed a significant difference between the two groups in the means of working memory in both auditory (P<0.001) and visual span (P<0.0001) as well as physical quality of life (P<0.04). Moreover, logistic regression analysis showed that MS disease had an impact on both physical (OR= .679 and CI= .889-.519) and mental (OR= .929 and CI= .857-.998) components of the quality of life.

Conclusion: Findings of the study indicate that cognition is an effective factor to engage in activities of daily living. Moreover, the relation between the working memory impairment and the quality of life in MS patients highlights the importance of the early recognition of cognitive deficit.

Keywords: Multiple sclerosis, Working memory, Quality of life, Wechsler adult intelligence scale
Full-Text [PDF 225 kb]   (1914 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2012/07/25 | Published: 2012/07/15


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Volume 16, Issue 4 (Bimonthly 2012) Back to browse issues page