[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 14, Issue 3 (Quarterly 2010) ::
Feyz 2010, 14(3): 190-199 Back to browse issues page
Protective effect of edible turmeric (Curcuma longa Linn.) powder on early hepatic injury in diabetic rats
Bahram Amouoghli Tabrizi *, Darush Mohajeri
, b_tabrizi@iaut.ac.ir
Abstract:   (9707 Views)

Background: Hepatic insufficiency is one of the most important consequences of the diabetes mellitus. A wide variety of herbs has been described for the treatment of diabetes mellitus. The aim of present study was to assess the protective effect of turmeric powder on early hepatic injuries in alloxan-induced diabetic rats.

Materials and Methods: Eighty male Wistar rats were randomly assigned into 4 equal groups. Turmeric powder was added to the food regimen of turmeric treatment groups. At the end of experiment, levels of functional liver markers (AST , ALT and SALP ), TB , Alb and TP were assessed in the serum. Product of lipid peroxidation (MDA), superoxide dismutase (SOD) activity, catalase (CAT), glutathione peroxidase (GPX) and glutathione reductase (GR) were also assayed in liver hemogenates. Finally, the biochemical findings were matched with histopathological verification.

Results: In the diabetic rats, turmeric powder significantly decreased the levels of serum biomarkers of hepathic injury, TB, and elevated the levels of Alb and TP. Furthermore, turmeric powder significantly decreased the lipid peroxidation and elevated the levels of antioxidant enzymes in the rats.

Conclusion: It seems that turmeric powder has protective effect on early diabetic hepatopathy in experimentally induced diabetic rats.

Keywords: Curcuma longa Linn., Diabetes mellitus, Hepatic injury, Rat
Full-Text [PDF 712 kb]   (3452 Downloads)    
Type of Study: Research | Subject: General
Received: 2010/09/27 | Published: 2010/10/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Amouoghli Tabrizi B, Mohajeri D. Protective effect of edible turmeric (Curcuma longa Linn.) powder on early hepatic injury in diabetic rats. Feyz. 2010; 14 (3) :190-199
URL: http://feyz.kaums.ac.ir/article-1-963-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 3 (Quarterly 2010) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4414