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:: Volume 12, Issue 3 (Quaterly 2008) ::
Feyz 2008, 12(3): 63-67 Back to browse issues page
Evaluation of the relationship between diabetes mellitus and kidney transplantation
Ali Reza Soleimani, Elahe Mianesaz *, Mohammad Reza Tamadon, Sayed Gholam Abbas Mousavi
, el_mianehsaz@yahoo.com
Abstract:   (8148 Views)

Background: Best choice for end stage renal disease (ESRD) is replacement therapy and kidney transplantation. Pre/post transplantation diabetes mellitus (DM) has adverse effects on both the patient and new kidney. In this study the effects of DM before and after the transplantation were compared with complications and outcomes of the procedure in kidney transplanted patients during 2002- 2007.

Materials and Methods: In this historical cohort study patients were divided into 3 groups: group I with DM before graft, group II with DM after the transplantation and group III left non diabetic. All information were evaluated based on the delayed function of graft (DGF), rejection possibility, systemic infections, cancer, relapse of renal disease, cardiovascular disease and subsequent death.

Results: One hundred five patients were included in this study (35 in each group). Mean age of the group I, II and III were 47, 47.3, and 47.1 respectively. Also, the incidence of outcomes and complications was 82.9%, 57.1% and 22.9% respectively. The one year survival of transplanted kidneys in each group was 68.5%, 77.1% and 91.4% and the one year survival of patients was 82.8%, 88.5% and 97.1% respectively.

Conclusion: The prevalence of post transplantation diabetes mellitus (PTDM) in this research was 21%. The rate of complications and death in pre transplantation DM patients was higher than that in PTDM patients. Also, this rate was the lowest in non diabetic patients. In conclusion, due to the adverse effects of DM or PTDM, the accurate follow up of patients in terms of blood sugar monitoring and complications is suggested.

Keywords: Kidney transplantation, Diabetes mellitus, PTDM
Full-Text [PDF 187 kb]   (2453 Downloads)    
Type of Study: Research | Subject: General
Received: 2009/03/19 | Published: 2008/10/15
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Soleimani A R, Mianesaz E, Tamadon M R, Mousavi S G A. Evaluation of the relationship between diabetes mellitus and kidney transplantation. Feyz. 2008; 12 (3) :63-67
URL: http://feyz.kaums.ac.ir/article-1-674-en.html

Volume 12, Issue 3 (Quaterly 2008) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
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