The Effect of Combined Aerobic–Resistance Training and Vitamin D3 Supplementation on Lipid Profile and Fasting Blood Glucose in Overweight Older Men

Ghiyami, Seyed Hamed; Arasti, Marziye; Mahmoodi, Roya; Rashid, Zahra; Kazemi, Reza

doi:10.48307/FMSJ.2026.30.3.335

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Volume 30, Issue 3 (Bimonthly 2026)

Feyz Med Sci J 2026, 30(3): 335-345

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The Effect of Combined Aerobic–Resistance Training and Vitamin D3 Supplementation on Lipid Profile and Fasting Blood Glucose in Overweight Older Men

Seyed Hamed Ghiyami ^*

Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran , hamedghiyami88@gmail.com

Abstract: (198 Views)

Background and Aim: Aging is associated with adverse changes in body composition and an increased risk of metabolic disorders. This study aimed to investigate the effect of combined aerobic–resistance training and vitamin D3 supplementation on lipid profile and fasting blood glucose in overweight older men.
Methods: In this quasi-experimental study, participants were divided into four groups: control, training, supplementation, and training+supplementation. The training program was conducted for 8 weeks, three sessions per week, with each session lasting 90 minutes. It included aerobic exercise at 50–70% of maximum heart rate and resistance exercise at 40–70% of one-repetition maximum. Participants in the supplementation groups received 5,000 IU of vitamin D3 weekly. Blood samples were collected 48 hours before and after the intervention. Data were analyzed using the paired t-test and analysis of covariance (ANCOVA) at a significance level of 0.05.
Results: After the intervention, blood glucose, triglyceride, total cholesterol, and LDL levels significantly decreased, while HDL levels significantly increased in the training and training+supplementation groups (P<0.05). The greatest changes were observed in the training+supplementation group. ANCOVA showed significant between-group differences in glucose (F=12.20, P=0.01), triglycerides (F=2.39, P=0.01), total cholesterol (F=2.56, P=0.002), LDL (F=3.41, P=0.01), and HDL (F=4.51, P=0.01).
Conclusion: Weekly supplementation with 5,000 IU of vitamin D3 combined with 8 weeks of aerobic–resistance training can significantly improve lipid profile and fasting blood glucose in overweight older men. These findings suggest that vitamin D3 supplementation may enhance the beneficial effects of combined exercise on metabolic parameters.

Keywords: Combined Exercise, Aerobic–Resistance Training, Lipid Profile, Vitamin D3, Fasting Blood Glucose, Overweight, Older Men

Full-Text [PDF 1027 kb] (40 Downloads)

Type of Study: Research | Subject: medicine, paraclinic
Received: 2026/05/21 | Revised: 2026/08/25 | Accepted: 2026/08/17 | Published: 2026/08/23

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Ghiyami S H, Arasti M, Mahmoodi R, Rashid Z, Kazemi R. The Effect of Combined Aerobic–Resistance Training and Vitamin D3 Supplementation on Lipid Profile and Fasting Blood Glucose in Overweight Older Men. Feyz Med Sci J 2026; 30 (3) :335-345
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