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:: Volume 29, Issue 6 (Bimonthly 2025) ::
Feyz Med Sci J 2025, 29(6): 637-645 Back to browse issues page
The relationship between pain catastrophizing and emotional symptoms with the level of kinesiophobia in patients with rheumatoid arthritis
Zhina Zarif khalili yazdani , Batool Zamani , Zahra Zanjani *
Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, Iran , z_zanjani2005@yahoo.com
Abstract:   (370 Views)
Background and Aim: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that, in addition to physical symptoms such as pain and limited mobility, is associated with various psychological factors. These factors, including anxiety, depression, stress, pain catastrophizing, and kinesiophobia (fear of movement), can significantly impact patients' function and quality of life. This study aimed to examine the correlation between emotional symptoms (anxiety, depression, stress), pain catastrophizing, and kinesiophobia in patients with rheumatoid arthritis.
Methods: This cross-sectional study evaluated 66 patients with RA, aged 18 to 60 years, who were referred to a rheumatology clinic in Kashan. Data were collected using standardized questionnaires: the Depression, Anxiety, and Stress Scale (DASS-21), the Pain Catastrophizing Scale (PCS), and the Tampa Scale for Kinesiophobia (TSK). After assessing data normality using the Shapiro–Wilk test, Pearson’s correlation coefficient was employed to analyze the relationships between variables using SPSS software.
Results: Significant correlations were found between the variables of anxiety, depression, stress, pain catastrophizing, and kinesiophobia (P < 0.01). The highest correlations were observed between anxiety and depression (r = 0.675) and between pain catastrophizing and kinesiophobia (r = 0.651). Significant associations were also found between anxiety and pain catastrophizing (r = 0.508) and between anxiety and stress (r = 0.668).
Conclusion: The findings of this study highlight the significant interplay of psychological factors in rheumatoid arthritis. It appears that emotional symptoms (particularly anxiety) and pain catastrophizing are directly associated with kinesiophobia. These results suggest the necessity of integrating psychological interventions, especially cognitive-behavioral therapy (CBT), alongside standard medical treatments for more comprehensive management of these patients and improvement of their functional outcomes.
Keywords: Rheumatoid arthritis, Anxiety, Depression, Pain catastrophizing, Kinesiophobia
Full-Text [PDF 438 kb]   (56 Downloads)    
Type of Study: Research | Subject: General
Received: 2025/06/7 | Revised: 2026/01/7 | Accepted: 2025/12/1 | Published: 2025/12/30
References
1. Smith MH, Berman JR. What Is Rheumatoid Arthritis? JAMA. 2022;327(12):1194. doi:10.1001/jama.2022.0786 PMid:35315883
2. Jamshidi AR, Banihashemi AT, Roknsharifi S, Akhlaghi M, Salimzadeh A, Davatchi F. Estimating the prevalence and disease characteristics of rheumatoid arthritis in Tehran: A WHO-ILAR COPCORD Study. Med J Islam Repub Iran. 2014; 28:93.
3. Quartana PJ, Campbell CM, Edwards RR. Pain catastrophizing: a critical review. Expert Rev Neurother. 2009; 9(5): 745-58. doi:10.1586/ern.09.34 PMid:19402782 PMCid:PMC2696024
4. Farchione TJ, Fairholme CP, Ellard KK, Boisseau CL, Thompson-Hollands J, Carl JR, et al. Unified protocol for transdiagnostic treatment of emotional disorders: a randomized controlled trial. Behav Ther. 2012; 43(3):666-78. doi:10.1016/j.beth.2012.01.001 PMid:22697453 PMCid:PMC3383087
5. Matcham F, Ali S, Irving K, Hotopf M, Chalder T. Are depression and anxiety associated with disease activity in rheumatoid arthritis? A prospective study. BMC Musculoskelet Disord. 2016;17:155. doi:10.1186/s12891-016-1011-1 PMid:27068100 PMCid:PMC4827220
6. Sheehy C, Murphy E, Barry M. Depression in rheumatoid arthritis--underscoring the problem. Rheumatology (Oxford). 2006;45(11):1325-7. doi:10.1093/rheumatology/kel231 PMid:16908510
7. Leeuw M, Goossens ME, Linton SJ, Crombez G, Boersma K, Vlaeyen JW. The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J Behav Med. 2007;30(1):77-94. doi:10.1007/s10865-006-9085-0. PMid:17180640
8. GBD 2021 Rheumatoid Arthritis Collaborators. Global, regional, and national burden of rheumatoid arthritis, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023;5(10):e594-e610. doi:10.1016/S2665-9913(23)00211-4 PMid:37795020
9. Green SB. How Many Subjects Does It Take To Do A Regression Analysis. Multivariate Behav Res. 1991; 26(3):499-510. doi:10.1207/s15327906mbr2603_7 PMid:26776715
10. Sahebi A, Asghari MJ, Salari RS. Validation of depression anxiety and stress scale (DASS-21) for an Iranian population. Iran J Developmental Psychol. 2025; 1(4): 36–54. doi:10.1016/S0037-6337(05)70907-4
11. Rahmati N, Asghari Moghadam MA, Shairi MR, Paknejad M, Rahmati Z, Ghassami M, et al. A Study of the Psychometric Properties of the Pain Catastrophizing Scale Amongst Iranian Patients with Chronic Persistent Pain. J Ilam Uni Med Sci. 2017;25(1):63-79. doi:10.29252/sjimu.25.1.63
12. Rahmati N, Asghari Moghadam M A, SHAIRI M, Paknejad M, Rahmati Z, Ghassami M, et al . A Study of the Psychometric Properties of the Pain Catastrophizing Scale Amongst Iranian Patients with Chronic Persistent Pain. J Ilam Uni Med Sci. 2017; 25(1):63-79. doi:10.29252/sjimu.25.1.63
13. Hudes K. The Tampa Scale of Kinesiophobia and neck pain, disability and range of motion: a narrative review of the literature. J Can Chiropr Assoc. 2011;55(3):222-32.
14. Jafari H, Ebrahimi I, Salavati M, Kamali M, Fata L. Psychometric Properties of iranian Version of Tampa Scale for Kinesiophobia in Low Back Pain Patients. J Rehab. 2010;11(1).
15. Thiagarajah AS, Guymer EK, Leech MT, Littlejohn GO. The relationship between fibromyalgia, stress and depression. Int J Clin Rheumatol. 2014;9(4):371-384. doi:10.2217/ijr.14.30
16. Peng B, Meng H, Guo L, Zhu J, Kong B, Qu Z, et al. Anxiety disorder and cardiovascular disease: a two-sample Mendelian randomization study. ESC Heart Fail. 2024;11(2):1174-1181. doi:10.1002/ehf2.14676 PMid:38279876 PMCid:PMC10966263
17. Getie A, Ayalneh M, Bimerew M. Global prevalence and determinant factors of pain, depression, and anxiety among cancer patients: an umbrella review of systematic reviews and meta-analyses. BMC Psychiatry. 2025;25:156. doi:10.1186/s12888-025-06599-5 PMid:39972435 PMCid:PMC11841195
18. Ionescu CE, Popescu CC, Agache M, Dinache G, Codreanu C. Depression in Rheumatoid Arthritis: Prevalence and Effects on Disease Activity. J Clin Med. 2024;13(7):2058. doi:10.3390/jcm13072058 PMid:38610822 PMCid:PMC11012436
19. Battat M, Omair N, WildAli MA, Alkaissi A, Amer R, Koni AA, et al. Assessment of depression symptoms among cancer patients: a cross-sectional study from a developing country. Sci Rep. 2024;14(1):11934. doi:10.1038/s41598-024-62935-x PMid:38789579 PMCid:PMC11126617
20. Fond G, Loundou A, Hamdani N, Boukouaci W, Dargel A, Oliveira J, et al. Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis. Eur Arch Psychiatry Clin Neurosci. 2014;264(8):651-60. doi:10.1007/s00406-014-0502-z PMid:24705634
21. Wilk M, Łosińska K, Pripp AH, Korkosz M, Haugeberg G. Pain catastrophizing in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: biopsychosocial perspective and impact on health-related quality of life. Rheumatol Int. 2022;42(4):669-682. doi:10.1007/s00296-021-05070-4 PMid:35098329
22. Yildirim N. Comparison of kinesiophobia in patients with rheumatoid arthritis and systemic lupus erythematosus. Eur Rev Med Pharmacol Sci. 2023; 27(23):11508-11516. doi:10.26355/eurrev_202312_34589.
23. Varallo G, Giusti EM, Scarpina F, Cattivelli R, Capodaglio P, Castelnuovo G. The Association of Kinesiophobia and Pain Catastrophizing with Pain-Related Disability and Pain Intensity in Obesity and Chronic Lower-Back Pain. Brain Sci. 2020; 11(1): 11. doi:10.3390/brainsci11010011 PMid:33374178 PMCid:PMC7823580
24. Giblon RE, Achenbach SJ, Myasoedova E, Davis JM 3rd, Kronzer VL, Bobo WV, et al. Trends in Anxiety and Depression Among Individuals With Rheumatoid Arthritis: A Population-Based Study. J Rheumatol. 2025;52(3):210-218. doi:10.3899/jrheum.2024-0165 PMid:39406405
25. Clark LA, Watson D. Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. J Abnorm Psychol. 1991; 100(3):316-36. doi:10.1037//0021-843X.100.3.316 PMid:1918611
26. Picavet HSJ, Vlaeyen JWS, Schouten JSAG. Pain Catastrophizing and Kinesiophobia: Predictors of Chronic Low Back Pain. Am J Epidemiol. 2002; 156(11): 1028-1034. doi:10.1093/aje/kwf136 PMid:12446259
27. Buer N, Linton SJ. Fear-avoidance beliefs and catastrophizing: occurrence and risk factor in back pain and ADL in the general population. Pain. 2002; 99(3):485-491. doi:10.1016/S0304-3959(02)00265-8 PMid:12406524
28. Pereira MG, Carvalho C, Costa ECV, Leite Â, Almeida V. Quality of life in chronic pain patients: Illness- and wellness-focused coping as moderators. Psych J. 2021;10(2):283-294. doi:10.1002/pchj.410. PMid:33378796
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Zarif khalili yazdani Z, Zamani B, Zanjani Z. The relationship between pain catastrophizing and emotional symptoms with the level of kinesiophobia in patients with rheumatoid arthritis. Feyz Med Sci J 2025; 29 (6) :637-645
URL: http://feyz.kaums.ac.ir/article-1-5354-en.html


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Volume 29, Issue 6 (Bimonthly 2025) Back to browse issues page
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