1. Zaki SS, Sawaf GE, Ahmed AA, Baess AI, Beshey BN, ELSheredy A. Pattern of antibiotic use and bacterial co-infection in hospitalized Covid-19 patients. Egyptian J Bronchol. 2023; 17(1): 20. doi:10.1186/s43168-023-00195-5

2. Organization WH. Coronavirus disease (COVID-19): weekly epidemiological update, 31 August 2020. 2020.

3. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020; 323(16): 1574-81. doi:10.1001/jama.2020.5394

4. Póvoa HCC, Chianca GC, Iorio N. COVID-19: An Alert to Ventilator-Associated Bacterial Pneumonia. Infect Dis Ther. 2020; 9(3): 417-20. doi:10.1007/s40121-020-00306-5

5. Sarton B, Grare M, Vardon-Bounes F, Gaubert A, Silva S, Crognier L, et al. Co-infection and ventilator-associated pneumonia in critically ill covid-19 patients requiring mechanical ventilation: a retrospective cohort study. Biomedicines. 2022; 10(8):1952. doi:10.3390/biomedicines10081952

6. Krumbein H, Kümmel LS, Fragkou PC, Thölken C, Hünerbein BL, Reiter R, et al. Respiratory viral co‐infections in patients with COVID‐19 and associated outcomes: A systematic review and meta‐analysis. Rev Med Virol. 2023; 33(1):e2365. doi:10.1002/rmv.2365

7. Sabery M, Shiri H, Moradiance v, Taghadosi M, Gilasi HR, Khamechian M. The frequency and risk factors for early-onset ventilator-associated pneumonia in intensive care units of Kashan Shahid-Beheshti hospital during 2009-2010. Feyz Med Sci J. 2013; 16(6): 560-9.

8. Ahmadipour M, Jafari M, Karami Robati F, Mobaraki Z. Bacterial Ventilator-Associated Pneumonia among Children and Adults in Intensive Care Unit in Shahid Bahonar Hospital, Kerman, Iran. J Mazandaran Univ Med Sci. 2021; 31(202): 142-8.

9. Barzegar F, Goli HR, Alikhani A, Farhadi M, Gholami M. Bacterial Profile of Ventilator-Associated Pneumonia and their Drug Susceptibility among Intensive Care Unit Patients. J Mazandaran Univ Med Sci. 2023; 33(224): 90-100.

10. Semenkovich TR, Frederiksen C, Hudson JL, Subramanian M, Kollef MH, Patterson GA, et al. Postoperative Pneumonia Prevention in Pulmonary Resections: A Feasibility Pilot Study. Ann Thorac Surg. 2019; 107(1): 262-70. doi:10.1016/j.athoracsur. 2018.08.008

11. Silva A, Silva TCD, Bom GJT, Vasconcelos RMB, Junior RS. Ventilator-associated pneumonia agents in Brazilian Neonatal Intensive Care Units - a systematic review. Braz J Infect Dis. 2018; 22(4): 338-44. doi:10.1016/j.bjid.2018.06.002

12. Antcliffe DB, Wolfer AM, O'Dea KP, Takata M, Holmes E, Gordon AC. Profiling inflammatory markers in patients with pneumonia on intensive care. Sci Rep. 2018; 8(1): 14736. doi:10.1038/s41598-018-32938-6

13. Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, et al. The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis. Influenza Other Respir Viruses. 2016; 10(5): 394-403. doi:10.1111/irv.12398

14. Huttner BD, Catho G, Pano-Pardo JR, Pulcini C, Schouten J. COVID-19: don't neglect antimicrobial stewardship principles! Clin Microbiol Infect. 2020; 26(7): 808-10. doi:10.1016/j.cmi.2020.04.024

15. Jain V, Vashisht R, Yilmaz G, Bhardwaj A. Pneumonia Pathology. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright © 2023, StatPearls Publishing LLC.; 2023.

16. Iosifidis E, Pitsava G, Roilides E. Ventilator-associated pneumonia in neonates and children: a systematic analysis of diagnostic methods and prevention. Future Microbiol. 2018; 13: 1431-46. doi:10.2217/fmb-2018-0108

17. Langford BJ, So M, Raybardhan S, Leung V, Westwood D, MacFadden DR, et al. Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis. Clin Microbiol Infect. 2020; 26(12): 1622-9. doi:10.1016/j.cmi.2020.07.016

18. Mahmoudi H. Bacterial co-infections and antibiotic resistance in patients with COVID-19. GMS Hyg Infect Control. 2020; 15: Doc35.

19. Ruffell A, Adamcova L. Ventilator-associated pneumonia: prevention is better than cure. Nurs Crit Care. 2008; 13(1): 44-53. doi:10.1111/j.1478-5153.2007.00248.x

20. Ghanizadeh A, Najafizade M, Rashki S, Marzhoseyni Z, Motallebi M. Genetic diversity, antimicrobial resistance pattern, and biofilm formation in Klebsiella pneumoniae isolated from patients with coronavirus disease 2019 (COVID-19) and ventilator-associated pneumonia. BioMed Res Int. 2021;2021. doi:10.1155/2021/2347872

21. james s Ll, Melvin p. performance standards for antimicrobial susceptibility testing. USA: www.clsi.org; 2023.

22. Nag VL, Kaur N. Superinfections in COVID-19 patients: role of antimicrobials. Dubai Med J. 2021; 4(2): 117-26. doi:10.1159/000515067

23. Russo A, Olivadese V, Trecarichi EM, Torti C. Bacterial ventilator-associated pneumonia in COVID-19 patients: data from the second and third waves of the pandemic. J Clin Med. 2022; 11(9): 2279. doi:10.3390/jcm11092279

24. Alikiaii B, Aghadavoudi O, Emami N. Evaluating Antibiotic Resistance Pattern of Ventilator-Associated Pneumonia in Intensive Care Units of Alzahra Hospital, Isfahan University of Medical Sciences, Iran. J Isfahan Med Sch. 2016; 34(399): 1083-9.

25. Sadeghi-Haddad-Zavareh M, Jouybari HA, Javanian M, Shokri M, Bayani M, Roushan MRH, et al. Antimicrobial resistance pattern in ventilator-associated pneumonia in an intensive care unit of Babol, northern Iran. J Acute Dis. 2018; 7(2):74-7. doi:10.4103/2221-6189.233015

26. Alikhani A, Najafi N, Davoudi A, Tiroum S, Khademloo MR, Tayyebi ME, et al. Microbiological and Minimum Inhibitory Concentration Study of Ventilator-associated Pneumonia Agents in Two University-associated Hospital Intensive Care Units in Mazandaran. Arch Clin Infect Dis. 2012; 8(1): 8-13. doi:10.5812/archcid.16034

27. Chi SY, Kim TO, Park CW, Yu JY, Lee B, Lee HS, et al. Bacterial pathogens of ventilator associated pneumonia in a tertiary referral hospital. Tuberc Respir Dis (Seoul). 2012; 73(1): 32-7. doi:10.4046/trd.2012.73.1.32

28. Kohbodi GA, Rajasurya V, Noor A. Ventilator-associated pneumonia. 2018.

29. Jain V, Vashisht R, Yilmaz G, Bhardwaj A. Pneumonia pathology. 2018.

30. Kar M, Siddiqui T, Dubey A, Hashim Z, Sahu C, Ghoshal U. Respiratory bacterial co-infections and their antibiotic resistance pattern in COVID-19 patients at a tertiary care centre in India. Access Microbiol. 2023; 5(6): 000514. v3. doi:10.1099/acmi.0.000514.v3

31. Jamnani AN, Montazeri M, Mirzakhani M, Moosazadeh M, Haghighi M. Evaluation of bacterial coinfection and antibiotic resistance in patients with COVID-19 under mechanical ventilation. SN Compr Clin Med. 2022; 4(1): 19. doi:10.1007/s42399-021-01114-9

32. Kyriakidis I, Vasileiou E, Pana ZD, Tragiannidis A. Acinetobacter baumannii Antibiotic Resistance Mechanisms. Pathogens. 2021; 10(3). doi:10.3390/pathogens10030373

33. Sharifipour E, Shams S, Esmkhani M, Khodadadi J, Fotouhi-Ardakani R, Koohpaei A, et al. Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU. BMC Infect Dis. 2020; 20:1-7. doi:10.1186/s12879-020-05374-z

34. Dash M, Padhi S, Pattnaik S, Mohanty I, Misra P. Frequency, risk factors, and antibiogram of Acinetobacter species isolated from various clinical samples in a tertiary care hospital in Odisha, India. Avicenna J Med. 2013; 3(4):97-102. doi:10.4103/2231-0770.120501

35. Blonz G, Kouatchet A, Chudeau N, Pontis E, Lorber J, Lemeur A, et al. Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients: a multicenter retrospective study in 188 patients in an un-inundated French region. Crit Care. 2021; 25(1):72. doi:10.1186/s13054-021-03493-w

36. Barbier F, Lisboa T, Nseir S. Understanding why resistant bacteria are associated with higher mortality in ICU patients. Intensive Care Med. 2016; 42(12): 2066-9. doi:10.1007/s00134-015-4138-x

37. Gragueb-Chatti I, Lopez A, Hamidi D, Guervilly C, Loundou A, Daviet F, et al. Impact of dexamethasone on the incidence of ventilator-associated pneumonia and blood stream infections in COVID-19 patients requiring invasive mechanical ventilation: a multicenter retrospective study. Ann Intensive Care. 2021; 11(1): 87. doi:10.1186/s13613-021-00876-8

38. Grasselli G, Tonetti T, Protti A, Langer T, Girardis M, Bellani G, et al. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study. Lancet Respir Med. 2020; 8(12): 1201-8. doi:10.1016/S2213-2600(20)30370-2

39. Doubravská L, Htoutou Sedláková M, Fišerová K, Klementová O, Turek R, Langová K, et al. Bacterial Community-and Hospital-Acquired Pneumonia in Patients with Critical COVID-19-A Prospective Monocentric Cohort Study. Antibiotics. 2024; 13(2): 192. doi:10.3390/antibiotics13020192

40. Hasanpour F, Neyestani Z, Arzanlou M, Moradi-Asl E, Sahebkar A, Khademi F. Vancomycin-resistant enterococci in Iran: A systematic review and meta-analysis of non-clinical studies. Gene Reports. 2021; 24: 101265. doi:10.1016/j.genrep.2021.101265

41. Gupta A, Agrawal A, Mehrotra S, Singh A, Malik S, Khanna A. Incidence, risk stratification, antibiogram of pathogens isolated and clinical outcome of ventilator associated pneumonia. Indian J Crit Care Med. 2011; 15(2): 96-101. doi:10.4103/0972-5229.83015

42. Joseph NM, Sistla S, Dutta TK, Badhe AS, Parija SC. Ventilator-associated pneumonia in a tertiary care hospital in India: incidence and risk factors. J Infect Dev Ctries. 2009; 3(10):771-7. doi:10.3855/jidc.396

43. Bird D, Zambuto A, O'Donnell C, Silva J, Korn C, Burke R, et al. Adherence to ventilator-associated pneumonia bundle and incidence of ventilator-associated pneumonia in the surgical intensive care unit. Arch Surg. 2010; 145(5): 465-70. doi:10.1001/archsurg.2010.69

44. Rello J, Diaz E. Pneumonia in the intensive care unit. Crit Care Med. 2003; 31(10): 2544-51. doi:10.1097/01.CCM.0000089928.84326.D2

45. Heyland DK, Cook DJ, Griffith L, Keenan SP, Brun-Buisson C. The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group. Am J Respir Crit Care Med. 1999;159(4 Pt 1):1249-56. doi:10.1164/ajrccm.159.4.9807050

46. Vacheron CH, Lepape A, Savey A, Machut A, Timsit JF, Comparot S, et al. Attributable Mortality of Ventilator-associated Pneumonia Among Patients with COVID-19. Am J Respir Crit Care Med. 2022; 206 (2):161-9. doi:10.1164/rccm.202202-0357OC

47. Auld S, Caridi-Scheible M, Blum JM, Robichaux CJ, Kraft CS, Jacob JT, et al. ICU and ventilator mortality among critically ill adults with COVID-19. medRxiv. 2020. doi:10.1101/2020.04.23.20076737

48. Wicky PH, Dupuis C, Cerf C, Siami S, Cohen Y, Laurent V, et al. Ventilator-Associated Pneumonia in COVID-19 Patients Admitted in Intensive Care Units: Relapse, Therapeutic Failure and Attributable Mortality-A Multicentric Observational Study from the OutcomeRea Network. J Clin Med. 2023; 12(4). doi:10.3390/jcm12041298

49. Afhami S, Hadadi A, Khorami E, Seifi A, Bazaz NE. Ventilator-associated pneumonia in a teaching hospital in Tehran and use of the Iranian Nosocomial Infections Surveillance Software. East Mediterr Health J. 2013; 19(10): 883-7. doi:10.26719/2013.19.10.883

50. Rousham EK, Nahar P, Uddin MR, Islam MA, Nizame FA, Khisa N, et al. Gender and urban-rural influences on antibiotic purchasing and prescription use in retail drug shops: a one health study. BMC Public Health. 2023; 23(1): 229. doi:10.1186/s12889-023-15155-3

51. Lee DS, Choe H-S, Kim HY, Yoo JM, Bae WJ, Cho YH, et al. Role of age and sex in determining antibiotic resistance in febrile urinary tract infections. Int J Infect Dis. 2016; 51: 89-96. doi:10.1016/j.ijid.2016.08.015

52. Dunn JE, Rudberg MA, Furner SE, Cassel CK. Mortality, disability, and falls in older persons: the role of underlying disease and disability. Am J Public Health. 1992; 82(3): 395-400. doi:10.2105/AJPH.82.3.395

53. Arvanitis M, Anagnostou T, Kourkoumpetis TK, Ziakas PD, Desalermos A, Mylonakis E. The Impact of Antimicrobial Resistance and Aging in VAP Outcomes: Experience from a Large Tertiary Care Center. PLOS ONE. 2014; 9(2): e89984. doi:10.1371/journal.pone.0089984

54. Combes A, Luyt CE, Fagon JY, Wollf M, Trouillet J-L, Gibert C, et al. Impact of methicillin resistance on outcome of Staphylococcus aureus ventilator-associated pneumonia. Am J Respir Crit Care Med. 2004; 170(7): 786-92. doi:10.1164/rccm.200403-346OC

55. Bouza E, Giannella M, Bunsow E, Torres M, Granda MP, Martín-Rabadán P, et al. Ventilator-associated pneumonia due to meticillin-resistant Staphylococcus aureus: risk factors and outcome in a large general hospital. J Hospital Infect. 2012; 80(2):150-5. doi:10.1016/j.jhin.2011.11.013