[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 28, Issue 3 (August-September 2024) ::
Feyz Med Sci J 2024, 28(3): 298-306 Back to browse issues page
Risk assessment of cancer due to chest CT radiation dose in COVID-19 patients at Shahid Beheshti Hospital, Kashan, Iran
Ahmadreza Najafi , Akbar Aliasgharzadeh * , Bagher Farhood , Mehran Mohseni , Habiballah Moradi
Department of Medical Physics, Faculty of Paramedicine, Kashan University of Medical Sciences, Kashan, Iran & Department of Medical Physics, Faculty of Paramedicine, Kashan University of Medical Sciences, Kashan, Iran , aliasgharzadeh_a@kaums.ac.ir
Abstract:   (725 Views)
Background and Aim: Exposure to ionizing radiation from repeated CT scan examinations increases the risk of solid cancers and leukemia. This study aims to evaluate the cancer risk associated with chest CT radiation doses in COVID-19 patients at Shahid Beheshti Hospital in Kashan, Iran.
Methods: Between January 20 and March 29, 2022, high-resolution chest CT images were obtained from 2,471 COVID-19 patients, with a mean age of 54 years. Using the average doses calculated by IndoseCT software, we estimated the Lifetime Attributable Risk (LAR) of major cancers for each patient, following the methodology outlined in the BEIR VII report.
Results: The mean effective dose was 3.47 millisieverts for women and 3.92 millisieverts for men. For men with COVID-19, lung cancer was identified as a major risk, with a mean LAR of 9.5 per 100,000 individuals. In women with COVID-19, lung, breast, and thyroid cancers were the major risk, with mean LARs of 19.7, 18.4, and 6.4 per 100,000 individuals, respectively. The overall mean LAR for solid cancers and leukemia across the entire population was estimated to be 19.4 and 1.7 per 100,000 individuals, respectively.
Conclusion: Despite a significant increase in chest CT examinations due to COVID-19 at Shahid Beheshti Hospital in Kashan, the overall cancer risk remains very low (LAR<20) according to the qualitative assessment by the World Health Organization.
Keywords: CT Dosimetry, Chest Imaging, COVID-19, Lifetime Attributable Risk, Cancer Risk
Full-Text [PDF 506 kb]   (165 Downloads)    
Type of Study: Research | Subject: General
Received: 2023/10/25 | Revised: 2024/09/8 | Accepted: 2024/07/21 | Published: 2024/08/31
References
1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan. China. Lancet 2020; 395(10223): 497–506. https://doi.org/10.1016/s0140-6736(20)30183-5.
2. Novel Coronavirus (2019-nCoV) situation reports. 2020.https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports .
3. Online statistics and information about the corona virus in Iran and the world - thanks to Afkar News based on the latest data from the World Health Organization (WHO).
4. There is a current outbreak of Coronavirus (COVID-19) disease.
5. Ghetti C, Ortenzia O, Maddalo M, Altabella L, Sverzellati N. Dosimetric and radiation cancer risk evaluation of high resolution thorax CT during COVID-19 outbreak. Phys Med. 2020; 80: 119-24.
6. Caruso D, Zerunian M, Polici M, Pucciarelli F, Polidori T, Rucci C, et al. Chest CT Features of COVID-19 in Rome, Italy. Radiology. 2020;296(2):E79-e85.
7. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, et al. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology. 2020;296(2):E115-e7.
8. Kanne JP, Little BP, Chung JH, Elicker BM, Ketai LH. Essentials for Radiologists on COVID-19: An Update-Radiology Scientific Expert Panel. Radiology. 2020;296(2):E113-e4.
9. Revel MP, Parkar AP, Prosch H, Silva M, Sverzellati N, Gleeson F, et al. COVID-19 patients and the radiology department - advice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI). Eur Radiol. 2020;30(9):4903-9.
10. Berrington de González A, Mahesh M, Kim KP, Bhargavan M, Lewis R, Mettler F, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med. 2009;169(22):2071-7.
11. Kang Z, Li X, Zhou S. Recommendation of low-dose CT in the detection and management of COVID-2019. Eur Radiol. 2020;30(8):4356-7.
12. Health Effects of Exposure to Low Levels of Ionizing Radiation: Beir V.
13. International Comission of Radiological Protection. 1990 Recommendations of the ICRP. Publication No. 60 Pergamon Press, New York,1991.
14. Gama Trejo G, Alvarez Romero JT, editors. Estimate of the genetically significant dose (GSD) in the Mexican population for the years 1996 and 1997. IRPA-10 Proceedings of the 10th international congress of the International Radiation Protection Association on harmonization of radiation, human life and the ecosystem; 2000; Japan: Japan Health Physics Society.
15. Zangeneh M, Deevband MR, Mohsenzadeh B. Lifetime attributable risk of cancer incidence and mortality in routine digital radiology procedures. Clin Imaging. 2020;67:226-36.
16. Tahmasebzadeh A, Paydar R, Soltani-Kermanshahi M, Maziar A, Reiazi R. Lifetime attributable cancer risk related to prevalent CT scan procedures in pediatric medical imaging centers. Int J Radiat Biol. 2021;97(9):1282-8.
17. Dio P, Anam C, Hidayanto E, Sutanto H, Asiah RH, Fatichah LN, et al. Evaluation of radiation dose accuracy calculated using IndoseCT software with direct measurement on polyester-resin phantoms. Radiat Physics Chem 2022; 201:110473.
18. Anam C, Mahdani F, Haryanto F, Widita R, Arif I, Syajaah K, et al. IndoseCT v20b: Software for calculating and managing radiation dose of computed tomography for an individual patient (Manual-English)2021.
19. Sahbaee P, Segars WP, Samei E. Patient-based estimation of organ dose for a population of 58 adult patients across 13 protocol categories. Med Physics. 2014;41(7):072104.
20. Ionizing CtAHRfEtLLo, Radiation NRC. Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2.424.
21. Elena Ivanovna M, Ivan Vasilievich I. Radiation Doses and Risk Assessment during Computed Tomography of the Chest in COVID-19 Patients. In: Reda RG, editor. Computed-Tomography (CT) Scan. Rijeka: IntechOpen; 2021. p. Ch. 3.
22. Mahmoudi G, Toolee H, Maskani R, Jokar F, Mokfi M, Hosseinzadeh A. COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study. BMC cancer. 2024;24(1):298.
23. World Health Organization. Communicating Radiation Risks in Paediatric Imaging: Information to Support Health Care Discussions about Benefit and Risk, 1st ed. World Health Organization: Geneva, Switzerland, 2016; p. 14–27
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Najafi A, Aliasgharzadeh A, Farhood B, Mohseni M, Moradi H. Risk assessment of cancer due to chest CT radiation dose in COVID-19 patients at Shahid Beheshti Hospital, Kashan, Iran. Feyz Med Sci J 2024; 28 (3) :298-306
URL: http://feyz.kaums.ac.ir/article-1-5024-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 28, Issue 3 (August-September 2024) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.05 seconds with 46 queries by YEKTAWEB 4660