Department of Internal Medicine, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, I.R. Iran. , esalat.kamal@yahoo.com
Abstract: (986 Views)
Background: Covid-19 disease was first reported in December 2019 in Wuhan, China.Inflammatory connective tissue diseases include rheumatoid arthritis and lupus, and non-inflammatory types include osteoarthritis and discopathy.This study was performed to compare the severity and risk of COVID-19 in patients with inflammatory and non-inflammatory connective tissue diseases.
Materials and Methods:This cross-sectional survey was performed on patients with COVID-19 with positive PCR in a population of 2370 patients with inflammatory connective tissue (1030 cases) and non-inflammatory patients (1340 cases).Sampling was performed by convenience method.The collected data were analyzed by SPSS software version 16.
Results: In this research, 190 patients (including 142 cases of inflammatory and 48 cases of non-inflammatory connective tissue disorders) with COVID-19. The risk of COVID-19 was estimated 8.01% in connective tissue cases, 13.8% in inflammatory connective tissue patients and 3.6% in cases with non-inflammatory types. Another finding of our study was a significant difference between the two groups of inflammatory and non-inflammatory connective tissue patients in terms of the severity of COVID-19, so that the severity of the infection was higher in the inflammatory group. Conclusion: The results of the present investigation show that the risk of COVID-19 is 3.8 times higher in patients with inflammatory connective tissue disorders than in patients with non-inflammatory connective tissue disorders.
Soleimani Z, Azadchehr M J, Mazi M, Esalatmanesh R, Saghazadeh A, Esalatmanesh K. Comparing the severity and risk of developing COVID-19 in patients with inflammatory and non-inflammatory connective tissue diseases. Feyz Med Sci J 2022; 26 (2) :201-211 URL: http://feyz.kaums.ac.ir/article-1-4581-en.html