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Comparing the severity and risk of developing COVID-19 in patients with inflammatory and non-inflammatory connective tissue diseases
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Zahra Soleimani    , Mahammad Javad Azadchehr , Mina Mazi , Roozbeh Esalatmanesh , Alireza Saghazadeh , Kamal Esalatmanesh * |
| Department of Internal Medicine, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, I.R. Iran. , esalat.kamal@yahoo.com |
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Abstract: (2766 Views) |
Background: Covid-19 disease was first reported in December 2019 in Wuhan, China. Inflammatory connective tissue diseases include rheumatoid arthritis and lupus, and non-inflammatory types include osteoarthritis and discopathy. This study was performed to compare the severity and risk of COVID-19 in patients with inflammatory and non-inflammatory connective tissue diseases.
Materials and Methods: This cross-sectional survey was performed on patients with COVID-19 with positive PCR in a population of 2370 patients with inflammatory connective tissue (1030 cases) and non-inflammatory patients (1340 cases). Sampling was performed by convenience method. The collected data were analyzed by SPSS software version 16.
Results: In this research, 190 patients (including 142 cases of inflammatory and 48 cases of non-inflammatory connective tissue disorders) with COVID-19. The risk of COVID-19 was estimated 8.01% in connective tissue cases, 13.8% in inflammatory connective tissue patients and 3.6% in cases with non-inflammatory types. Another finding of our study was a significant difference between the two groups of inflammatory and non-inflammatory connective tissue patients in terms of the severity of COVID-19, so that the severity of the infection was higher in the inflammatory group.
Conclusion: The results of the present investigation show that the risk of COVID-19 is 3.8 times higher in patients with inflammatory connective tissue disorders than in patients with non-inflammatory connective tissue disorders. |
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| Keywords: Inflammatory connective tissue diseases, Non-inflammatory connective tissue diseases, Risk of infection, COVID-19 |
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Full-Text [PDF 346 kb]
(2100 Downloads)
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Type of Study: Research |
Subject:
medicine, paraclinic
Received: 2022/03/19 | Revised: 2022/08/15 | Accepted: 2022/05/14 | Published: 2022/05/30
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