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:: Volume 25, Issue 1 (Bimonthly 2021) ::
Feyz 2021, 25(1): 743-751 Back to browse issues page
The effect of 8 weeks of curcumin supplementation consumption on muscle injury and inflammatory response following an acute strength activity in male futsal players
Ali Ahmadzadeh , Ameneh Pourrahim-Ghouroghchi * , Roghayeh Afroundeh
Department of Sport Physiology, Faculty of Faculty of Educational Sciences and Psychology, University of Mohaghegh-e-Ardabili, Ardabil, I.R. Iran. , amenehpoorrahim@yahoo.com
Abstract:   (1151 Views)
Background: Curcumin supplementation consumption is effective in reducing muscle damage and inflammation sport performance. This study aimed to effect of eight weeks of curcumin supplementation consumption on muscle injury and inflammation following an acute session of strength activity in male futsal players.
Materials and Methods: Twenty male futsal players (age (year): 26.06±3.88 and BMI: 24.4±3.17) volunteered to participate in the study and were randomly assigned to supplementation and control groups. Blood sampling was performed in four stages. After the first blood sampling from both supplementation and control groups, one acute session of circular strength training in 5 stations and 3sets with 75%1RM were performed. The second blood sampling was performed. Forty-eight hours later, the experimental group used 150 mg curcumin supplementation tablet, 3 days a week during 8 weeks. Forty-eight hours after the last using, blood sampling was performed in both groups. Both supplementation and control groups performed the second acute circular strength training and one hour later, the fourth stage blood sampling was performed. Control group consumed placebo during 8 weeks. Data were analyzed using SPSS software version 25 using mixed analysis of variance.
Results: The results showed that 8 weeks curcumin supplementation consumption, significantly decreased creatine kinase, white blood cells,  neutrophils and monocytes following acute second strength activity (P<0.05). However, Lymphocytes did not change significantly (P>0.05).
Conclusion: It seems that curcumin supplementation consumption can reduce exercise-induced muscle injury and inflammation in male futsal players. So, it is recommended that male futsal coaches and players use curcumin supplements to reduce muscle damage and inflammation after an acute strength activity.
Keywords: Resistance training, Curcumin supplementation, Creatine kinase, White blood cells
Full-Text [PDF 1198 kb]   (395 Downloads)    
Type of Study: Research | Subject: General
Received: 2020/05/9 | Accepted: 2021/01/30 | Published: 2021/04/6
1. Harty PS, Cottet ML, Malloy JK, Kerksick CM. Nutritional and supplementation strategies to prevent and attenuate exercise-induced muscle damage: a brief review. J Sports Med 2019; 5(1): 1-17.
2. Laoruengthana A, Poosamsai P, Fangsanau T, Supanpaiboon P, Tungkasamesamran K. The epidemiology of sports injury during the 37th Thailand National Games 2008 in Phitsanulok. J Med Assoc Thai 2009; 92(Suppl 6): S204-10.
3. Timmons BW, Tarnopolsky MA, Snider DP, Bar-Or O. Immunological changes in response to exercise: Influence of age, puberty, and gender. MSSE 2006; 38(1): 293-304.
4. Assumpcao Cdo, Lima Lcr, Oliveira Fbd, Greco Cc, Denadai BS. Exercise-induced muscle damage and running economy in humans. Sci World J 2013; 16(1): 78-89.
5. Jakeman Jr, Macrae R and Eston R. A single 10- min bout of cold-water immersion therapy after strenuous plyometric exercise has no beneficial effect on recovery from the symptoms of exercise-induced muscle damage. Ergonomics 2009; 52(4): 256-60.
6. Brancaccio P, Maffulli N, Buonauro R, Limongelli FM. Serum enzyme monitoring in sports medicine. Clin Sports Med 2008; 27(1): 521-18.
7. Hammouda O, Chtourou H, Chaouachi A, Chahed H, Ferchichi S, Kallel C, et al. Effect of short-term maximal exercise on biochemical markers of muscle damage, total antioxidant status, and homocysteine levels in football players. Asian J Sports Med 2012; 3(4): 239-46.
8. Eshghi N, Khodaparast MH, Hosseini F, Boloorian S. Comparing antioxidant efficiency of curcumin with natural and artificial antioxidants in food model system (soybean oil). Innov Food Sci Technol 2013; 5(1): 13 - 22.
9. Gupta SK, Kumar B, Nag TC, Agrawal SS, Agrawal R, Agrawal P, et al. Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms. J Ocul Pharmacol 2011; 27(2): 123- 30.
10. Khan IA, Abourashed EA. Leung's encyclopedia of common natural ingredients used in food, drugs, and cosmetics. A John Wiley & Sons, Inc. New York 2010, 10(1): 604-5.
11. Jagetia GC, Aggarwal Bb. "Spicing up" of the immune system by curcumin. Journal of Clinical Immunology. J Clin Immunol 2007; 27(1): 19 - 35.
12. Hatcher H, Planalp R, Cho J, Toti F M, Torti SV. Curcumin: from ancient medicine to current clinical trials Adv Exp Med Biol 2008; 65(11): 1631-52.
13. Aggarwal BB, Sundaram C, Malani N, Ichikawa H. Curcumin: The Indian solid gold. Clin Cancer Res 2007; 595(1): 1-75.
14. Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, et al. Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance. Clin Cancer Res 2004; 10: 6847 - 54.
15. Noorani Pilehrood M, Namani F, Ebadi Ghahremani M. The effect of curcumin supplementation on the antioxidant enzymes in the blood of Girls basketball players after helpless activity. Appl Findings Sports Sci 2016; 1(1): 25-35. [in Persian]
16. Drobnic F, Joan R, Giovanni A, Stefano T, Federico F, Xavier V, et al. Reduction of delayed onset muscle soreness by a novel curcumin delivery system: a randomised, placebo-controlled trial. J Int Soc Sports Nutr 2014; 11(31): 10-1186.
17. Mahmoudi HamidAbad S, Nakhosti Rouhie B. The effect of acute curcumin use on total antioxidant capacity and selected indicators of delayed muscle contraction after an intense extracorporeal activity session. J Appl Exerc Physiol 2017; 26(1): 12-22. [in Persian]
18. Rowsell GJ, Coutts AJ, Reaburn P, Hill-Haas S. Effects of cold-water immersion on physical performance between successive matches in high-performance junior male soccer players J Sports Sci 2009; 27(6): 465-73.
19. Nicol LM, David SR, Ruth FA, John KE. Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS). Eur J Appl Physiol 2015; 115(8): 1769-77.
20. Mark D, Murphy A, Carmichael M, Zielinski M, Groschwitz C, Brown A, et al. Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damage. J Physiol Regul Integr Comp Physiol 2007; 292: 2168-73.
21. Pourrahim Ghouroghchi A, Pahlevani M. Effects of maximal and sub-maximal resistance exercise on muscle damage, inflammation, intrinsic antioxidant in non-athlete men. Koomesh 2020; 22(2): 351-8. [in Persian]
22. Mayhew JL, Johnson BD, Lamonte MJ, Lauber D, Kemmler W. Accuracy of prediction equations for determining one repetition maximum bench press in women before and after resistance training. J Strength Cond Res 2008; 22(5): 1570-77.
23. Hotfiel T, Mayer I, Huettel M, Hoppe M, Engelhardt M, Christoph L. Accelerating Recovery from Exercise-Induced Muscle Injuries in Triathletes: Considerations for Olympic Distance Races. J Sports 2019; 7(1): 143.
24. Walton GR, Kate KJ, Mula CS, Fry BD, Jason SE. Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth. Sci Rep 2019; 9(1): 969.
25. Vasconcelos ES. Inflammatory response induced by resistance exercise. MOJ Immunol 2018; 6(4): 110‒3.
26. Foroughi Pardanjani, A, Ebrahimi M, Changizi M. The effect of a session of resistance exercise on muscle injury and delayed muscle soreness in male athlete students. Research in Academic Sport 2013; 8: 37-52. [in Persian]
27. Hosseini Kakhak SA, Eldarabadi A, Haghighi, AH, Sharifian Z. Effect of a session of resistance training with vascular obstruction and without vascular obstruction of Lactate dehydrogenase and creatine kinase serum in young girls. Sport physiology 2016; 30(1): 51-64. [in Persian]
28. Nemati Gh. Rahmani F, Mirzaei B. The effect of eccentric contraction on blood hematological changes in non-athlete young men. Sport Physiol 2012; 15: 71-82.
29. Barquilha G, Uchida M, Santos V, Moura N, Lambertucci R, Hatanaka E, et al. Characterization of the effects of one maximal repetition test on muscle injury and inflammation Markers. Br J Sports Med 2011; 41(1): 523-30.
30. Matos F, Eduardo B, Claudio RV. Effect of cold-water immersion on elbow flexors muscle thickness after resistance training. J Strength Cond Res 2017; 32(3): 1756-63.
31. Tsai1 SW, Huang CC, Hsu YJ, Chen CJ, Lee PY, Huang YH, et al. Accelerated muscle recovery after in vivo curcumin supplementation. Natural Product Communications. J Biol Chem 2020; 15(1): 1-9.
32. Fernandez-Lazaro D, Mielgo-Ayuso J, Seco Calvo J, Cordova Martínez A, Caballero García A, Fernandez-Lazaro C. Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review. Nutrients 2020; 12: 501.
33. Huang WC, Chiu WC, Chuang HL, Tang DW, Lee ZM, Fu LW, et al. Effect of curcumin supplementation on physiological fatigue and physical performance in mice. Nutrients 2015; 7: 905-21.
34. Samadi M, Kordi N, Salehpoor S, Mohajer Iravani O, Asjodi F. Effect of one and five-day curcumin consumption on muscle damage indices after an eccentric exercise session in untrained young men. J Military Med 2019; 21(2): 123-30. [in Persian]
35. Islamizadeh At, Younesian A. Investigating the effect of one week of taking curcumin supplementation after one session of resistance activity on the indicators of muscle damage, oxidative stress and delayed muscle contraction in active men. [Dissertation or Thesis] Shahroud. Faculty of Physical Education, Shahroud University 2016. [in Persian]
36. Jager R, Purpura M, Kerksick CM. Eight Weeks of a High Dose of Curcumin Supplementation May Attenuate Performance Decrements Following Muscle-Damaging Exercise. Nutrients 2019; 11: 1692.
37. Basham SA, Waldman HS, Krings BM, Lamberth J, Smith JW, McAllister MJ. Effect of curcumin supplementation on exercise-induced oxidative stress, inflammation, muscle damage, and muscle soreness. J Diet Suppl 2019; 26: 1-14.
38. Hewlings SJ, Kalman DS. Curcumin: A Review of Its’ effects on human health. Foods 2017; 6: 92.
39. Banaifar AA, Shahkennedy H, Behbooditabrizi L. The effect of curcumin supplementation and eight weeks of endurance training on antioxidant indices of liver tissue in male rate. Iran J Nut Sci Food Indurt 2016; 11(4): 36-46.
40. Anand P, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, Sung B, et al. Biological activities of curcumin and its analogues (Congeners) made by man and mother nature. Biochem Pharmacol 2008; 76: 1590-611.
41. Epstein J, Sanderson IR, MacDonald TT. Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies. Br J Nutr 2010; 103 (11): 1545-57.
42. Hanai H, Iida T, Takeuchi K, Watanabe F, Maruyama Y, Andoh A, et al. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. CGH 2006; 4 (12): 1502-6.
43. Sokmen M, Akram Khan M. The antioxidant activity of some curcuminoids and chalcones. Inflammopharmacol. J Biol Chem 2016; 24: 81-6.
44. Mullaicharam A, Maheswaran A, Pharmacological effects of curcumin J Nutr Pharmacol Neurol Dis 2012; 2: 92-9.
45. Barzegar A, Moosavi-Movahed A. Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PLoS ONE 2011; 6(10): 26012.
46. Tomita M, Kawakami H, Uchihara Jn, Okudaira T, Masuda M, Takasu N, et al. Curcumin (diferuloylmethane) inhibits constitutive active NF-κB, leading to suppression of cell growth of human T‐cell leukemia virus type I‐infected T-cell lines and primary adult T‐cell leukemia cells. Int J Cancer 2006; 118 (3): 765-72.
47. Mirzaei H, Shakeri A, Rashidi B, Jalili A, Banikazemi Z, Sahebkar A. Phytosomal curcumin: A review of pharmacokinetic, experimental an clinical studies. Biomed Pharmacother 2017; 85: 102-12.
48. Fuller B, Dijk S, Butler P, Hoang V, Davidson B. Pro-inflammatory agents accumulate during donor liver cold preservation: a study on increased adhesion molecule expression and abrogation by curcumin in cultured endothelial cells. Cryobiology 2003; 46(3): 284-8.
49. Maithilikarpagaselvi N, Sridhar MG, Swaminathan RP, Zachariah B. Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases. Chem Biol Interact 2016; 244: 187-94.
50. Moohebati M, Yazdandoust S, Sahebkar A, Mazidi M, Sharghi-Shahri Z, Ferns G, et al. Investigation of the effect of short-term supplementation with curcuminoids on circulating small dense lowdensity lipoprotein concentrations in obese dyslipidemic subjects: A randomized doubleblind placebo-controlled cross-over trial. ARYA Atherosclerosis 2014; 10(5): 280-6.
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Ahmadzadeh A, Pourrahim-Ghouroghchi A, Afroundeh R. The effect of 8 weeks of curcumin supplementation consumption on muscle injury and inflammatory response following an acute strength activity in male futsal players. Feyz. 2021; 25 (1) :743-751
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