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:: Volume 23, Issue 5 (Bimonthly 2019) ::
Feyz 2019, 23(5): 476-484 Back to browse issues page
Effects of Rhus Coriaria essential oil on depression and anxiety in male rats
Yosef Golshani , Saeed Mohammadi * , Majid Golshani
Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, I.R. Iran. , smiauhphd.sm@gmail.com
Abstract:   (2979 Views)
Background: Depression and anxiety are among the most important diseases of human being. The chemical drugs used to treat these diseases have side effects, therefore, the use of medicinal herbs such as Rhus Coriaria can be effective in treating these diseases with regard to properties such as anti-oxidant activity. In this study, the effects of oral administration of Rhus Coriaria fruit essential oil (RCFEO) was investigated on depression and anxiety in male rats.
Materials and Methods: In this experimental study, adult male Wistar rats were divided into control, RCFEO (50, 100, and 300 mg/kg), fluoxetine (depression reference drug) and alprazolam (anxiety reference drug) groups. In order to evaluate the depression and anxiety, forced swimming and elevated plus maze tests were used, respectively.
Results: In the forced swimming test, there were significant differences between the RCFEO (100 and 300 mg/kg) and the control group in aspect of the immobility time (P<0.05, P<0.001) as well as climbing time (P<0.05, P<0.01), respectively. In addition, the results from the elevated plus maze test showed that the percent of entries into open arms are significantly different between 300 mg/kg of RCFEO and control that way this index had increased by using RCFEO (300 mg/kg) (P<0.001).
Conclusion: This experimental study indicates that administration of Rhus Coriaria fruit essential oil (orally) probably can improve depression and anxiety in male rats.
Keywords: Depression, Anxiety, Rhus Coriaria, Rat
Full-Text [PDF 241 kb]   (1247 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2019/03/6 | Revised: 2019/12/15 | Accepted: 2019/07/17 | Published: 2019/12/16
References
1. Weinberger A, Gbedemah M, Martinez A, Nash D, Galea S, Goodwin R. Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups. Psychol Med 2018; 48(3): 1305-8.
2. Ripper CA, Boyes ME, Clarke PJ, Hasking PA. Emotional reactivity, intensity, and perseveration: Independent dimensions of trait affect and associations with depression, anxiety, and stress symptoms. Pers Individ Dif 2018; 121(7): 93-9.
3. De Carvalho RSM, Duarte FS, de Lima TCM. Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behav Brain Res 2011; 221(6): 75-82.
4. Zarei M, Mohammadi S, Shahidi S, Fallahzadeh AR. Effects of Sonchus asper and apigenin-7-glucoside on nociceptive behaviors in mice. J Pharm Pharmacogn Res 2017; 5(4): 217-27.
5. Zarei M, Mohammadi S, Komaki A. Antinociceptive Activity of Inula britannica L. and Patuletin: In vivo and Possible Mechanisms Studies. J Ethnopharmacol 2018; 219: 351-8.
6. Mohammadi S, Zarei M, Zarei MM, Salehi I. Effect of hydroalcoholic leaves extract of Rhus Coriaria on pain in male rats. Anesth Pain Med 2016; 6(1): e32128.
7. Rayne S, Mazza G. Biological activities of extracts from sumac (Rhus spp.): a review. Plant Foods Hum Nutr 2007; 62(4): 165-75.
8. Ayoka A, Akomolafe R, Iwalewa E, Ukponmwan OE. Studies on the anxiolytic effect of Spondias mombin L. (Anacardiaceae) extracts. Afr J Tradit Complement Altern Med 2005; 2(2): 153-65.
9. Ishola IO, Awodele O, Eluogu CO. Potentials of Mangifera indica in the treatment of depressive-anxiety disorders: possible mechanisms of action. J Complement Integr Med 2016; 13(5): 275-87.
10. Mohammadi S, Oryan Sh, Komaki A, Eidi A, Zarei M. Effects of Hippocampal Microinjection of Irisin, an Exercise-Induced Myokine, on Spatial and Passive Avoidance Learning and Memory in Male Rats. Int J Pept Res Ther 2019; 25: 1-11.
11. Pick CG. Strain differences in mice antinociception: relationship between alprazolam and opioid receptor subtypes. Eur Neuropsychopharmacol 1996; 6(3): 201-5.
12. Golshani Y, Zarei M, Mohammadi S. Acute/Chronic Pain Relief: Is Althaea officinalis Essential Oil Effective? Avicenna J Neuro Psycho Physio 2015; 2(4): e36586.
13. Fallahzadeh AR, Mohammadi S. An investigation of the antinociceptive and anti-inflammatory effects of hydroalcoholic extract of Inula helenium on male rats. JBUMS 2016; 18(12): 57-63. [in Persian]
14. Sartim AG, Brito BM, Gobira PH, Joca SR. Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test. Behav Pharmacol 2019; 30(1): 59-66.
15. Walia V, Garg C, Garg M. NO-sGC-cGMP signaling influence the anxiolytic like effect of lithium in mice in light and dark box and elevated plus maze. Brain Res 2019; 1704: 114-26.
16. Zarei M, Mohammadi S, Jabbari S, Shahidi S. Intracerebroventricular microinjection of kaempferol on memory retention of passive avoidance learning in rats: involvement of cholinergic mechanism(s). Int J Neurosci 2019; 129: 11-23.
17. Mohammadi S, Golshani Y. Neuroprotective Effects of Rhamnazin as a Flavonoid on Chronic Stress-Induced Cognitive Impairment. J Adv Neurosci Res 2017; 4(2): 30-7.
18. Aburawi SM, Al-Tubuly R, Alghzewi E, Gorash Z. Effects of calcium channel blockers on antidepressant action of Alprazolam and Imipramine. Libyan J Med 2007; 2(4): 169-75.
19. Mahmoudi M, Mohammadi S, Shahidi S. Antinociceptive effect of hydroalcoholic leaf extract of Hedera helix in male rat. Sci J Hamadan Univ Med Sci 2013; 20(2): 119-25. [in Persian]
20. Emamghoreishi M, Khasaki M, Aazam MF. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol 2005; 96(3): 365-70.
21. Dhingra D, Goyal PK. Inhibition of MAO and GABA: probable mechanisms for antidepressant-like activity of Nardostachys jatamansi DC. in mice. Brain Res 2008; 21(3): 33-41.
22. Galdino PM, Nascimento MVM, Florentino IF. The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice. Prog Neuropsychopharmacol Biol Psychiatry 2012; 38(2): 276-84.
23. Tong-Un T, Wannanon P, Wattanathorn J, Phachonpai W. Quercetin liposomes via nasal administration reduce anxiety and depression-like behaviors and enhance cognitive performances in rats. Am J Pharmacol Toxicol 2010; 5(2): 80-8.
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Golshani Y, Mohammadi S, Golshani M. Effects of Rhus Coriaria essential oil on depression and anxiety in male rats. Feyz 2019; 23 (5) :476-484
URL: http://feyz.kaums.ac.ir/article-1-3834-en.html


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Volume 23, Issue 5 (Bimonthly 2019) Back to browse issues page
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