[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 22, Issue 5 (Bimonthly 2018) ::
Feyz 2018, 22(5): 497-502 Back to browse issues page
Cytokines response during a month of detraining in trained and overweight men
Mahmoud Nikseresht * , Abdolhossein Taherikalani
Department of Exercise Physiology, Ilam Branch, Islamic Azad University, Ilam, I. R. Iran. , nikserasht@gmail.com
Abstract:   (174 Views)
Background: Training-induced physiological adaptations reduced during detraining, but researches are limited about the comparison of the effects of detraining after different types of training. Thus, the aim of this study was to compare the effects of one month detraining on cytokines concentrations in aerobic- (AT) and resistance trained (RT) and overweight men.
Materials and Methods: In this quasi-experimental study, 19 trained men (25-38 years) were assigned to RT (n=10) and AT (n=9) groups, based on the types of training. The groups were matched by the physical activity level, age and body mass index. The subjects avoided to perform any exercises for a month. All subjects were taken blood samples to measure serum levels of interleukin (IL)-10, IL-17A, and IL-20 before and after the detraining period.
Results: After 4 weeks of detraining, body fat percentage and waist circumference increased significantly in the AT and RT groups, while the maximal oxygen consumption in these groups was significantly decreased (for all variables, P<0.05). The concentration of IL-17A (P=0.049) showed a significant increase only in the RT group; however, no significant differences were noted for IL-10 and IL-20 concentrations in response to the detraining period in both groups (both, P>0.05).
Conclusion: It seems that the negative effects caused by one month of detraining are more prominent in the RT group (increase in IL-17A).
Keywords: Interleukin-17, Maximal oxygen consumption, Cessation of training, Active men
Full-Text [PDF 243 kb]   (20 Downloads)    
Type of Study: Research | Subject: General
Received: 2018/04/4 | Accepted: 2018/07/31 | Published: 2018/11/28
1. Dandona P, Aljada A, Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 2004; 25(1): 4-7.
2. Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, et al. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007; 116(11): 1234-41.
3. Janssen I, Katzmarzyk PT, Ross R. Body mass index, waist circumference, and health risk: evidence in support of current National Institutes of Health guidelines. ArchIntern Med 2002; 162(18): 2074-9.
4. Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006; 17(1): 4-12.
5. Calcaterra V, De Amici M, Klersy C, Torre C, Brizzi V, Scaglia F, et al. Adiponectin, IL-10 and metabolic syndrome in obese children and adol-escents. Acta Biomed 2009; 80(2): 117-23.
6. Pedersen BK. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem 2006; 42: 105-17.
7. Sanjabi S, Zenewicz LA, Kamanaka M, Flavell RA. Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity.CurrOpinPharmacol 2009; 9(4): 447-53.
8. Sabat R. IL-10 family of cytokines. Cytokine Growth Factor Rev 2010;21(5):315-24.
9. Sabat R, Grutz G, Warszawska K, Kirsch S, Witte E, Wolk K, et al. Biology of interleukin-10. Cytokine Growth Factor Rev 2010; 21(5): 331-44.
10. Wegenka UM. IL-20: biological functions mediated through two types of receptor complexes. Cytokine Growth Factor Rev 2010; 21(5): 353-63.
11. Ahmed M, Gaffen SL. IL-17 in obesity and adipogenesis. Cytokine Growth Factor Rev 2010; 21(6): 449-53.
12. Smith E, Prasad KM, Butcher M, Dobrian A, Kolls JK, Ley K, et al. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation 2010; 121(15): 1746-55.
13. Zuniga LA, Shen WJ, Joyce-Shaikh B, Pyatnova EA, Richards AG, Thom C, et al. IL-17 regulates adipogenesis, glucose homeostasis, and obesity. J Immunol 2010; 185(11): 6947-59.
14. Thompson D, Markovitch D, Betts JA, Mazzatti D, Turner J, Tyrrell RM. Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: a rand‌omiz‌ed-controlled trial. J Appl Physiol 2010; 108 (4): 769-79.
15. Pavlik G, Major Z, Csajagi E, Jeserich M, Kneffel Z. The athlete's heart. Part II: influencing factors on the athlete's heart: types of sports and age (review). Acta Physiol Hung 2013; 100(1): 1-27.
16. Gill JM, Caslake MJ, McAllister C, Tsofliou F, Ferrell WR, Packard CJ, et al. Effects of short-term detraining on postprandial metabolism, endothelial function, and inflammation in endurance-trained men: dissociation between changes in triglyceride metabolism and endothelial function. J Clin Endo-crinolMetab 2003; 88(9): 4328-35.
17. Olsen RH, Krogh-Madsen R, Thomsen C, Booth FW, Pedersen BK. Metabolic responses to reduced daily steps in healthy nonexercising men. JAMA 2008; 299(11): 1261-3.
18. Lund AJ, Hurst TL, Tyrrell RM, Thompson D. Markers of chronic inflammation with short-term changes in physical activity. Med Sci Sports Exerc2011; 43(4): 578-83.
19. Jackson AS, Pollock ML. Generalized equa-tions for predicting body density of men. 1978. Br J Nutr 2004; 91(1): 161-8.
20. Theodorou AA, Panayiotou G, Volaklis KA, Douda HT, Paschalis V, Nikolaidis MG, et al. Aerobic, resistance and combined training and detr-aining on body composition, muscle strength, lipid profile and inflammation in coronary artery disease patients. Res Sports Med 2016; 24(3): 171-84.
21. Hwang PS, Andre TL, McKinley-Barnard SK, Marroquín M, Flor E, Gann JJ, et al. Resistance training–induced elevations in muscular strength in trained men are maintained after 2 weeks of detraining and not differentially affected by whey protein supplementation. J Strength Cond Res 2017; 31(4): 869-81.
22. Pedlar CR, Brown MG, Shave RE, Otto JM, Drane A, Michaud-Finch J, et al. Cardiovascular response to prescribed detraining among recre‌a-tional athletes. J Appl Physiol 2017; 124(4): 813-20.
23. Rønnestad BR, Hansen J, Hollan I, Spencer M, Ellefsen S. Impairment of performance variables after in-season strength-training cessation in elite cyclists. Int J Sports Physiol Perform 2016; 11(6): 727-35.
24. Hosseini A, Hassanpour Q, Noura M, Kheirdeh M, Hosseini Z. The effect of swimming training and detraining on interleukin-17 and interleukin-18 of rats. J Shahrekord Univ Med Sci 2017; 19(4): 1-11. [in Persian]
25. Nikseresht M, Agha-Alinejad H, Azarbayjani MA, Ebrahim K. Effects of nonlinear resistance and aerobic interval training on cytokines and insulin resistance in sedentary men who are obese. J Strength Cond Res 2014; 28(9): 2560-8.
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nikseresht M, Taherikalani A. Cytokines response during a month of detraining in trained and overweight men. Feyz. 2018; 22 (5) :497-502
URL: http://feyz.kaums.ac.ir/article-1-3572-en.html

Volume 22, Issue 5 (Bimonthly 2018) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3790