History and Objectives: Rodents act as a repository of many common diseases of human beings and this leads to economical and health problems. Considering the different incidence of parasitic contamination on mice and rats in Iran, this study was carried out to determine the incidence of intestinal parasites in Kashan in 1997.

Materials and Methods: The descriptive strategy of this study was conducted on 120 domestic and wild mice. They were randomly trapped and after anesthesia, the worms of their intestinal tract were isolated, fixed in 10% formalin and stained. Data were then analyzed statistically.

Results: contamination rate of wild and domestic mice for intestinal parasites in the region was 79.2%. It was 75.9% for Merionus libicus, 54.8% for Rombomis epimus, 100% for Gerbilus nanus, 100% for Jaculus belenfordi, 94% for Ratus and 85.7% for Mouse musculus. In this study 6 species of nematodes, 4 species for cystodes and 4 species of intestinal protozoa were identified. The common parasites for human and rodents were Syphacia obvelata (34.2%), Aspicularis tetraptera (14.2%), Humanolyps nana fraterna (10.8%), H.diminuta (4.2%), Congylonema (1.7%) and Trichuris muris (1.7%). In this regard the rare cystode Meggittina was isolated for the first time in Iran.

Conclusion and Recommendations: Contamination rate for common parasites was rather high in the region. Therefore, it is essential to consider rodents as a repository of intestinal parasites, defense against it and health training programs for its control and prevention.