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:: Volume 22, Issue 3 (Bimonthly 2018) ::
Feyz 2018, 22(3): 248-257 Back to browse issues page
The effect of resistance training and genistein on leptin and lipid profile of streptozotocin-induced diabetic rats
Seyyed Ali Hosseini , Mozhgan Ahmadi , Anahita Sharifi , Saeideh Shadmehri , Abdossaleh Zar
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, I. R. Iran. , alihoseini_57@yahoo.com
Abstract:   (3445 Views)
Background: Diabetes is a chronic disease which can lead to increased levels of leptin and lipid profile. The aim of this study was to examine the effect of resistance training and genistein on leptin and lipid profile of streptozotocin-induced diabetic rats.
Materials and Methods: In this experimental study, 56 diabetic rats were divided into 7 groups of 8 rats including control, resistance training, 30 mg/kg genistein consumption, 10 mg/kg genistein consumption, resistance training and 30 mg/kg genistein consumption, resistance training and 10 mg/kg genistein consumption, and sham. The training groups performed a resistance training program for 8 weeks and 5 sessions per week.
Results: Resistance training had a significant effect on reduction of leptin, triglyceride, cholesterol and very-low-density lipoprotein (VLDL) (P≤0.05). Genistein consumption had a significant effect on reduction of leptin and increased high-density lipoprotein (HDL) levels (P≤0.05) and had no effect on reduction of triglyceride, cholesterol, LDL and very low-density lipoprotein (VLDL) (P≥0.05). Resistance training along with genistein consumption had an interactional effect on reduction of leptin, triglyceride, cholesterol, LDL, and VLDL and increased HDL (P≤0.05). Also, 10 mg/kg and 30 mg/kg genistein consumption had similar effects on reduction of leptin and increased HDL levels in diabetic rats (P≥0.05).
Conclusion: Resistance training along with genistein consumption has interactional effects on leptin and lipid reduction in streptozotocin-induced diabetic rats.
Keywords: Diabetes, Resistance training, Genistein, Leptin, Lipid profile
Full-Text [PDF 352 kb]   (980 Downloads)    
Type of Study: Research | Subject: General
Received: 2017/12/30 | Revised: 2018/08/14 | Accepted: 2018/06/18 | Published: 2018/08/4
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Hosseini S A, Ahmadi M, Sharifi A, Shadmehri S, Zar A. The effect of resistance training and genistein on leptin and lipid profile of streptozotocin-induced diabetic rats. Feyz 2018; 22 (3) :248-257
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Volume 22, Issue 3 (Bimonthly 2018) Back to browse issues page
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