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The Effect of Resistance Training and Genistein on Leptin and Lipid Profile of Streptozotocin Induced Diabetic Rats
Seyyed Ali Hosseini * , Mozhgan Ahmadi , Anahita Sharifi , Saeideh Shadmehri , Abdossaleh Zar
, alihoseini_57@yahoo.com
Abstract:   (188 Views)
Background: Diabetes is chronic disease which induces increase in leptin and lipid profile. The aim of this study was to review the effect of resistance training and genistein on leptin and lipid profile of diabetic rats.
Material and Methods: Fifty six diabetic rats selected and divided in 7 groups of 8 rats (1) control, (2) resistance training, (3) 30 mg/kg genistein consumption, (4) 10 mg/kg genistein consumption, (5) resistance training with 30 mg/kg genistein consumption, (6) resistance training with 10 mg/ kg genistein consumption, and (7) sham. Groups 2, 5, and 6 performed resistance exercises for eight weeks and five sessions per week. For statistical analysis of data used independent t test, two way ANOVA and bonferroni post hoc tests (p≤0.05).
Results: Resistance training has significant effect on reduction of leptin, triglyceride, cholesterol and VLDL (p≤0.05) nevertheless has no significant effect on reduction of LDL (p≥0.05); genistein consumption has significant effect on reduction of leptin and increase of HDL (p≤0.05) nevertheless has no significant effect on reduction of triglyceride, cholesterol, LDL and VLDL (p≥0.05); resistance training with genistein consumption has interactional effects on reduction of leptin, triglyceride, cholesterol, LDL and VLDL and increase of HDL (p≤0.05) also 10 and 30 mg/kg genistein have equal effects on reduction of leptin and increase of HDL in diabetic rats (p≥0.05).
Conclusion: It appears that resistance training with simultaneous consumption of genistein has leptin and lipid lowering interactional effects in streptozotocin induced diabetic rats.
Keywords: Diabetes, Resistance Training, Genistein, Leptin, Lipid Profile
     
Type of Study: Research | Subject: General
Received: 2017/12/30 | Accepted: 2018/06/18
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