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:: Volume 5, Issue 4 (Quarterly 2002) ::
Feyz 2002, 5(4): 1-5 Back to browse issues page
Relationship between Migraine acute attacks and changes in Prolactin secretion
Behnam Seddighi * , Mahmoud Reza Dehghani
Abstract:   (13430 Views)

History and Objectives: Considering the high incidence of migraine attacks and significance of a knowledge of its pathogenesis and the hypothesis of using serum prolactin level as a marker of its diagnosis, this study was carried out to find out a relationship on referrals of Kerman neuroscience center.

Materials and Methods: This study was carried out on 20 cases with a definite diagnosis of migraine and 20 cases with non-migraine headache according to HIS criterion. Blood prolactin level was measured before attacks and drug consumption and during attacks and data were statistically analyzed.

Results: Out of 40 patients, case group had a reduction in prolactin level from 5.3±3.7 to 4.4±2.4 and control group had a reduction from 5.7±2.9 to 5.4±3.4. In addition, the difference was not significant.

Conclusion and Recommendations: There was not any increase in serum prolactin during acute attacks of migraine. It is recommended to conduct more studies for evaluation of increased dopaminergic activity as a key causative factor of migraine.

Keywords: Migraine headache, Intolerable headache, Prolactin
Full-Text [PDF 863 kb]   (1754 Downloads)    
Type of Study: Research | Subject: General
Received: 2008/11/10 | Revised: 2008/11/10 | Published: 2002/01/15
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Seddighi B, Dehghani M R. Relationship between Migraine acute attacks and changes in Prolactin secretion . Feyz 2002; 5 (4) :1-5
URL: http://feyz.kaums.ac.ir/article-1-342-en.html

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Volume 5, Issue 4 (Quarterly 2002) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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