[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 6, Issue 4 (Quarterly 2003) ::
Feyz 2003, 6(4): 38-44 Back to browse issues page
Efficacy of Streptokinase, Magnesium sulfate and their combination in acute anterior myocardial infarction
Mohamamd Khani , Habib Allah Nourizade
Abstract:   (7827 Views)

Background: Anterior myocardial infarction is relatively a common problem with increasing prevalence. Controversies have arisen regarding the efficacy of streptokinase or magnesium sulfate therapy. The present study was conducted to determine the efficacy of streptokinase, magnesium sulfate and their combination as well as their side effects in patients with anterior acute myocardial infarction, referring to Shaheed Beheshti hospital in Kashan between 1995-97.

Materials and Methods: It was an existing data type study. Diagnosis was made according to the physical exam, history, EKG findings and elevated enzyme level. Patients were assigned in any of the four groups: Routine drug users (Control n=50), routine drug+streptokinase (n=51), routine drug+magnesium sulfate (n=47), routine drug+magnesium sulfate+streptokinase (Group IV n=48). History of previous MI or disabling disease was our exclusion criteria.

Results: The study population included 153 males and 43 females with the mean age of 61.7±10.54 years. Patients were matched according to the age, sex and blood pressure. The mean days of hospitalization were 12.4±2.8 and 8±1.7 in-group IV and control subjects, respectively. For these groups the mean reduction in blood pressure was 52% and 20.8%, respectively (P<0.05). Patients who received streptokinase as well as magnesium have shown lesser side effects (Hemodynamic, mechanical, pericarditis and aneurysm). Death was reported in 12.2% of patients.

Conclusion: It seems as if combination therapy with magnesium sulfate and streptokinase is associated with better outcomes and less side effects.

Keywords: Acute anterior myocardial infarction, Streptokinase, Sulfate magnesium
Full-Text [PDF 1141 kb]   (1823 Downloads)    
Type of Study: Research | Subject: General
Received: 2008/11/8 | Revised: 2008/11/8 | Published: 2003/01/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Khani M, Nourizade H A. Efficacy of Streptokinase, Magnesium sulfate and their combination in acute anterior myocardial infarction . Feyz 2003; 6 (4) :38-44
URL: http://feyz.kaums.ac.ir/article-1-302-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 6, Issue 4 (Quarterly 2003) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.05 seconds with 46 queries by YEKTAWEB 4645