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:: Volume 20, Issue 1 (Bimonthly 2016) ::
Feyz 2016, 20(1): 25-32 Back to browse issues page
Relationship between some immunological indexes and maximal oxygen pulse in active girls: effect of a bout of intense aerobic physical activity
Bakhtiar Tartibian, Maryam Shabani, Bahman Ebrahimi-Torkamani *
Urmia University , Ebrahimi.ba96@yahoo.com
Abstract:   (2180 Views)

Background: The aim of this study was to determine the relationship between T lymphocytes (CD4+, CD8+), NK (CD56+), CD4+/CD8+ ratio and maximal oxygen pulse among the active girls in response to an intense aerobic physical activity.

Materials and Methods: This semi-experimental study was conducted on 20-25 years old active women. To estimate maximal oxygen pulse and immune response parameters, GXT treadmill test was performed. In order to evaluate the immune system response to intense physical activity, blood samples were obtained at 3 times (before, immediately after and 2 hours after the exercise).

Results: The T-CD4+cells and CD4+/CD8+ rations were significantly decreased after an intense aerobic physical activity (P<0.05). However, the levels of CD8+ and CD56+ cells were significantly increased after the same physical activity. The results also showed a significant positive relationship between maximal oxygen pulse and CD8+,  CD56+ cells level (r=0.699, P<0.001), (r=0.49, P≤0.009). In addition, there was a significant negative relationship between maximal oxygen pulse and CD4+ (r=-0.645, P≤0.008), CD4+/CD8+ T-cell ratios (r= - 0.539, P<0.002).

Conclusion: The findings of this research showed that in active women the maximal oxygen pulse, as an indicator of the efficiency of the cardiovascular system, has strong relationship with some immune system parameters.

Keywords: Active girls, Exercise, T CD4+, CD8+, Natural killer cell, Maximal oxygen pulse
Full-Text [PDF 281 kb]   (1106 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2016/04/11 | Accepted: 2016/04/11 | Published: 2016/04/11
References
1. Abbas A, Lichtman A, Pober J. Cellular and molecular immunology. 8th ed. Philadelphia: Bsaunders; 2012. p. 25-75.
2. Gaal K, Sun N, Hernandez A, Arber D. Sinonasal NK/T cell lymphomas in the united states. Am J Surg Pathol 2000; 24(11): 1511-17.
3. Lower T, Padgett DA, Woods JA. Moderate exercise early after influenza virus infection reduces the th1 inflammatory response in lungs of mice. Exerc Immunol Rev2006; 12(4): 97-111.
4. Kapasi ZF, Mcrae ML, Ahmed R. Suppression of viral specific primary T cell response following intense physical exercise in young but not old mice. J Appl Physiol 2005; 98(2): 663-71.
5. Huang CJ, Webb HE, Garten RS, Kamimori GH, Acevedo EO. Psychological stress during exercise: Lymphocyte subset redistribution in firefighters. Physiol Behav 2010; 101(3): 320-6.
6. Kakanis MW, Peake J, Brenu EW, Simmonds M, Gray B, Hooper SL, et al. The open window of susceptibility to infection after acute exercise in healthy young male elite athletes. Exerc Immunol Rev 2010; 16: 119-37.
7. Bell E, Spartshott S, Bunce C. CD4+ T cell memory, CD45R subsets and the persistence of antigen: a unifying concept. Immunol Today 1998; 19(2): 60-4.
8. Timmons B, Cieslak T. Human natural killer cell subsets and acute exercise: a brief review. Exerc Immunol Rev 2008; 14: 8-23.
9. Northoff H, Symons S, Zieker D, Schaible EV, Schafer K, Thoma S, et al. Gender- and menstrual phasedependent regulation of inflammatory gene expression in response to aerobic exercise. Exerc Immunol Rev 2008; 14: 86-103.
10. Haus E, Smolensky MH. Biologi rythms in the immune system. Chronobiol Int 1999; 16(5): 581-622.
11. Timmons B, Tarnopolsky, M, Snider D, Bar-O. Immunological changes in response to exercise: influence of age, puberty, and gender. Med Sci Sport Exerc 2006; 38(2): 293-304.
12. Allgrove JE, Geneen L, Latif S, Gleeson M. Influence ofa fed or fasted state on the s-IgA response to prolonged cycling in active men and women. Int J Sport Nutr Exerc Metab 2009; 19(3): 209-21.
13. Michael G. Immune Function in Sport and Exercise. J Appl Physiol 2007; 103: 693–9.
14. Lavie CJ, Milani RV, Mehra MR. Peak exercise oxygen pulse and prognosis in chronic heart failure. Am J Cardiol 2004; 93(5): 588-93.
15. McCann DJ. Body Size and Vo2 Peak: A New Prespective? Int J Sport Med 2004; 25(1): 50-5.
16. Benschop RJ, Geenen R, Mills PJ, Naliboff BD, Kiecolt-Glaser JK, Herbert TB, et al. Cardiovascular and Immune Response to Acute Psychological Stress in Young and Old Women: A Meta-Analysis. Psychosom Med 1998; 60(3): 290-6.
17. Huang CJ, Webb HE, Garten RS, Kamimori GH, Acevedo EO. Psychological stress during exercise:Lymphocyte subset redistribution in firefighters. Physiol Behav 2010; 101(3): 320-6.
18. George JD, Vehrs PR, Allsen PE, Fellingham GW, Fisher AG. Development of a submaximal treadmill jogging test for fit collegeaged individuals. Med Sci Sport Exerc 1993; 25(5): 643-7.
19. Wasserman K, Hansen J, Sue M, William W, Kathy E, Xing G. Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications. 5nd ed. Hardcover Publishers; 2011. p. 315.
20. Bieger WP, Weiss M, Michel G, Weicher H. Exercise induce monocytosis and modulation of monocyte function. Int J Sports Med 1980; 10(1): 30-6.
21. Ghafourian BM, Habibi A, Zadkarami M, Nikbakht M, Parsaei-Far A. Effect of one session incremental exhaustive pedaling with hand on T and NK cells response of immune system of athlete students. J Shaheed Sadoughi Univ Med Sci 2010; 18(5): 436-43. [in Persian]
22. Hiscock N, Pedersen BK. Exercise-induced immunodepression- plasma glutamine is not the link. J Appl Physiol (1985) 2002; 93(3): 813-22.
23. Pedersen BK, Hoffman-Goetz L. Exercise and immune system: regulation, integration, and adaptation. Physiol Rev 2000; 80(3): 1055-81.
24. McFarlin BK, Flynn MG, Stewart LK, Timmerman KL. Carbohydrate intake during endurance exercise increases natural killer cellresponsiveness to IL-2. J Appl Physiol 2004; 96(1): 271-5.
25. Peake J, Peiffer JJ, Abbiss CR, Nosaka K, Okutsu M, Laursen PB, et al. Body temperature and its effect on leukocyte mobilization, cytokines and markers of neutrophil activation during and after exercise. Eur J Appl Physiol 2008; 102(4): 391-401.
26. Moyna NM, Acker GR, Fulton JR, Weber K, Goss FL, Robertson RJ, et al. Lymphocyte function and cytokine production during incremental exercise in active and sedentary males and females. Int J Sports Med 1996; 17(8): 585-91.
27. Gleeson M, Nieman DC, Pedersen BK. Exercise, nutrition and immune function. J Sports Sci 2004; 22(4): 115-25.
28. Morgado JP, Monteiro CP, Matias CN, Alves F, Pessoa P, Reis J, et al. Sex-Based Effects on Immune Changes Induced by a Maximal Incremental Exercise Test in Well-Trained Swimmers. J Sports Sci Med 2014; 13(3): 708-14.
29. Kullo IJ, Khaleghi M, Hensrud DD. Markers of inflammation are inversely associated with VO2 max in asymptomatic men. J Appl Physiol 2007; 102(4): 1374-9.
30. Benschop RJ, Geenen R, Mills PJ, Naliboff BD, Kiecolt-Glaser JK, Herbert TB, et al. Cardiovascular and Immune Response to Acute Psychological Stress in Young and Old Women: A Meta-Analysis. Psychosom Med 1998; 60(3): 290-6.
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Tartibian B, Shabani M, Ebrahimi-Torkamani B. Relationship between some immunological indexes and maximal oxygen pulse in active girls: effect of a bout of intense aerobic physical activity. Feyz. 2016; 20 (1) :25-32
URL: http://feyz.kaums.ac.ir/article-1-2968-en.html


Volume 20, Issue 1 (Bimonthly 2016) Back to browse issues page
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