[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 19, Issue 4 (Bimonthly 2015) ::
Feyz 2015, 19(4): 356-363 Back to browse issues page
Detection of antibiotic resistance patterns in Staphylococcus aureus strains isolated from patients admitted to Isfahan hospitals during 2014-2015
Fahimeh Nourbakhsh, Hasan Momtaz *
Islamic Azad University, Shahrekord Branch, , hamomtaz@yahoo.com
Abstract:   (3870 Views)

Background: Staphylococcus aureus is one of the most important pathogens that cause disease and death in humans and animals in Iran and around the world. This study was conducted to detect antibiotic resistance genes and antibiotic susceptibility patterns in S. aureus strains isolated from patients admitted to Isfahan hospitals during 2014-2015.

Materials and Methods: In this cross-sectional study, S. aureus isolates were collected from patients referred to the health centers in Isfahan Province, Iran. The isolates were separated using the laboratory standard methods. Antibiotic susceptibility patterns of the isolates were determined using the disk-diffusion method. Furthermore, the presence of genes responsible for antibiotic resistance including tet M, tet K, and mec A were investigated using the multiplex-polymerase chain reaction method.

Results: Phenotypic evaluation showed that the highest antibiotic resistance was seen for methicillin (90.2%), erythromycin (89.7%), ciprofloxacin (89.5%), penicillin (88%), tetracycline (82.4%), and gentamycin (75.8%) and the lowest resistance level was seen for nitrofurantoin (2%) and vancomycin (10%). Molecular study showed the presence of mec A (93%), tet M (78%) and tet K (21%) in the isolates.

Conclusion: The results of this study compared with the results of other studies show an increase in drug resistance of S. aureus isolates.

Keywords: Staphylococcus aureus, Antibiotic resistance, Nosocomial infectious
Full-Text [PDF 258 kb]   (18969 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2015/10/11 | Accepted: 2015/10/11 | Published: 2015/10/11
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nourbakhsh F, Momtaz H. Detection of antibiotic resistance patterns in Staphylococcus aureus strains isolated from patients admitted to Isfahan hospitals during 2014-2015. Feyz. 2015; 19 (4) :356-363
URL: http://feyz.kaums.ac.ir/article-1-2788-en.html


Volume 19, Issue 4 (Bimonthly 2015) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4071