[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Guide for Authors::
Online Submission::
Ethics::
Articles archive::
For Reviewers::
Contact us::
::
Basic and Clinical Biochemistry and Nutrition
..
DOAJ
..
CINAHL
..
EBSCO
..
IMEMR
..
ISC
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
enamad
..
:: Volume 18, Issue 6 (Bimonthly 2015) ::
Feyz 2015, 18(6): 524-530 Back to browse issues page
The hemostatic effect of aluminum sulfate in liver bleeding in rat
Saeed Nouri , Mohammad Reza Sharif , Mehrdad Hosseinpour , Hasan Ehteram
Kashan University of Medical Sciences , dr.mrsharif@yahoo.com
Abstract:   (5559 Views)
Background: Despite great advances in the field of surgery, the control of liver parenchymal hemorrhage is still one of the challenges surgeons face in saving the patients’ lives. Aluminum sulfate is used as a hemostatic agent in dental surgery. This study aimed to examine the hemostatic effect of aluminum sulfate on controlling bleeding from liver parenchymal tissue.
Materials and Methods: In this experimental study, 60 male Wistar rats were randomly allocated into six equal groups of 10 mice each. An incision ( 2 cm length 0.5 cm depth) was made on each rat's liver surface and the length of time to hemostasis as a dependent variable was measured using different concentrations of aluminum sulfate (5%, 10%, 15%, 25%, and 50%) against the control method (control of bleeding by suturing) as the independent variable. The liver tissue was examined for pathological changes.
Results: The length of time to hemostasis in the aluminum sulfate groups was significantly less than that of the control group (P<0.01). The pathologic examination showed the highest frequency of low-grade inflammation based on the defined pathological grading.
Conclusion: Aluminum sulfate is an effective hemostatic agent with low-grade inflammation effect in controlling the bleeding from liver parenchymal tissue in an animal model.
Keywords: Hemostasis, Aluminum sulfate, Liver, Rat
Full-Text [PDF 253 kb]   (1312 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2015/01/4 | Revised: 2015/01/7 | Accepted: 2015/01/4 | Published: 2015/01/4
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nouri S, Sharif M R, Hosseinpour M, Ehteram H. The hemostatic effect of aluminum sulfate in liver bleeding in rat. Feyz 2015; 18 (6) :524-530
URL: http://feyz.kaums.ac.ir/article-1-2471-en.html


Creative Commons License
This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 18, Issue 6 (Bimonthly 2015) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
Persian site map - English site map - Created in 0.05 seconds with 46 queries by YEKTAWEB 4645