Background: The presence of heavy metals in higher concentrations and more than their permissible levels in our environment is of great concern because of their toxicity. These metals enter the environment through different ways (e.g. industrial activities).

Materials and Methods: This study has quantified the contaminants in fish muscular tissue samples and followed the guidelines of U.S. Environmental Protection Agency (EPA) to estimate their hazard indices. The samples taken from Abramis brama were collected from Anzali Lagoon. Spectroscopic techniques were used for determination of Cd (Cadmium), Cr (Chromium) in fish muscular tissue.

Results: The concentration of Cr (0.88±0.09 µg/g dry wight) was higher compared with Cd (0.19±0.02 µg/g dry wight) the concentrations of other metals were not higher than the maximum permissible level. The suggested hazard index<1 was acceptable for dairy intake of human.

Conclusion: Although the heavy metals analyzed in Abramis brama from Anzali did not pose any immediate health risk to humans but due to the bioaccumulation and magnification of these heavy metals in humans, it is essential to reach safeguard levels of the metals in the environment.