Background: Radioactive strontium, which is produced from reactors, could be found throughout the nature and even in low doses can be carcinogenic. High-energy beta from strontium radiation, in addition to damage to the blood system and bone marrow, can lead to osteoporosis in the trabecular bone, sclerosis and increasing the wounds of bones. Also, the excess amount of strontium can engender osteomalacia and osteoporosis, and then impede the natural maturation of chondrocytes in the epiphyseal plate of long bones.

Materials and Methods: Web sites of Pubmed and Elsivier were searched for the related articles.

Results: The results showed that calcium can be replaced by strontium in the biological processes of the body due to its chemical similarities, and by attaching to ligands like hydroxyapatite, mineral component of the bone and also a range of binding proteins to calcium, which play a role in the physiological deposition of calcium in the cells, can be normally substituted by calcium and cause irreversible damages to the human body.

Conclusion: The most compounds of strontium are soluble in water and it can be harmful for body because strontium can leave the bone and enter the bloodstream and circulate throughout the body. One of the fastest ways for strontium to enter the bloodstream and biological processes is breathing. Therefore, the body's protection against ingress and uptake of strontium should be taken into consideration.