TY - JOUR JF - KAUMS JO - Feyz VL - 21 IS - 3 PY - 2017 Y1 - 2017/8/01 TI - Evaluation of an auditory brainstem response in icteric neonates TT - بررسی پاسخ شنوایی ساقه مغز (ABR) در نوزادان مبتلا به زردی N2 - Background: Neonatal hyperbilirubinemia is a common and preventable cause of sensory-neural hearing impairment, which can cause difficulties in the development of speech and communication. This study was conducted to detect the toxic effect of hyperbilirubinemia on the brain stem and auditory tract in neonates with icterus admitted to Shahid Beheshti Hospital in Kashan, Iran. Materials and Methods: This cross-sectional study was conducted on 98 neonates with increased indirect bilirubin admitted to Shahid Beheshti Hospital in Kashan during 2014-2015. The patients were referred to Matini Hospital for the assessment of the auditory brainstem response (ABR); wave latency and interpeak intervals of the waves were also evaluated. According to the serum bilirubin level, the neonates were allocated into two groups; one group had a serum bilirubin level of 13-20 mg/d and another group had a bilirubin level more than 20 mg/d. Results: From 98 neonates, 26 (26.5%) had a bilirubin level more than 20 mg/d and 72 (73.5%) had a bilirubin level of 13-20 mg/d. Also, 46.1% of the neonates in the first group (bilirubin< 20 mg/d) and 2.8% of the neonates in the second group (bilirubin 13-20 mg/d) had abnormal ABR (P<0.0001). There was a significant difference between the mean latency time of III and V waves and the interpeak intervals of I-III, I-V, and III-V waves in neonates of the two groups (P<0.05). Conclusion: An increased indirect bilirubin level (>20 mg/d) can cause an auditory processing disorder in neonates. So, performing ABR for screening and early detection of bilirubin toxicity can be recommended as a necessary audiologic intervention in all cases of severe neonatal hyperbilirubinemia. SP - 292 EP - 297 AU - Talebian, Ahmad AU - Jahangiri, Mohammad AU - Sharif, Mohammad Reza AU - Moraveji, Seyyed Alireza AU - Kheirkhah, Davood AU - Ghorbani, Monireh AU - Hojjati, Maryam AU - Talebian, Motahareh AD - Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, I. R. Iran. KW - Neonates KW - Icter KW - Auditory brainstem response UR - http://feyz.kaums.ac.ir/article-1-3404-en.html ER -