AU - Karkhaneh, Somaieh AU - Abrishamib, Alireza AU - Gharaeic, Babak AU - Vagheitabar, Reza AU - Alborzi Avanaki, Mahsa AU - Samadian, Fariba AU - Zare, Ali AU - Karkhaneh, Leyla TI - The effect of diabetes mellitus on clinical, biochemical indications and mortality in patients with COVID-19; an analytical cross sectional study PT - JOURNAL ARTICLE TA - KAUMS JN - KAUMS VO - 25 VI - 6 IP - 6 4099 - http://feyz.kaums.ac.ir/article-1-4441-en.html 4100 - http://feyz.kaums.ac.ir/article-1-4441-en.pdf SO - KAUMS 6 ABĀ  - Background: Coronavirus infection in patients with pre-existing diabetes mellitus has been shown to indicate a poorer outcome compared to non-diabetic cases. This study aimed to explore disease severity and mortality in patients infected with Coronavirus 2019 disease (COVID-19) between these two groups. Materials and Methods: The current analytical cross sectional study reviewed the medical records of 99 patients hospitalized with laboratory-confirmed COVID-19 from February 14th to February 26th, 2020. The cases were divided into non-diabetic (n=77) and diabetic (n=22) groups. The differences in clinical symptoms, biochemical parameters, length of hospital stay, CT scan analysis, and the proportion of the patients with the outcome of mortality were compared. Results: The statistical analysis illustrated that most of the patients were male, and compared to non-diabetic, patients with diabetes were significantly older (P=0.01). Results indicated a considerable increase in ALP, vitamin D, pO2 levels of serum and a decrease in SpO2 (P<0.05). The patients with co-existing metabolic disorders, such as cardiovascular diseases were significantly higher in the diabetic group (P<0.05). Statistics evaluation did not show significant differences between the two groups in terms of other assessed factors and CT images. Conclusion: Based on the current study, it seems that diabetic and non-diabetic patients have almost similar clinical and paraclinical findings, so additional investigations with larger sample sizes are needed to achieve more accurate results. CP - IRAN IN - Department of Physiology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran LG - eng PB - KAUMS PG - 1314 PT - Review YR - 2021