TY - JOUR T1 - Antibiotic susceptibility pattern and the prevalence of Staphylococcus aureus isolated from skin and soft tissue in Tehran Razi skin hospital (2014-15) TT - بررسی فراوانی استافیلوکوکوس اورئوس جدا شده از عفونت های پوست و بافت نرم و تعیین الگوی حساسیت آنتی بیوتیکی بیماران مراجعه کننده به بیمارستان پوست رازی تهران طی سال های 94-1393 JF - KAUMS JO - KAUMS VL - 21 IS - 2 UR - http://feyz.kaums.ac.ir/article-1-3359-en.html Y1 - 2017 SP - 188 EP - 196 KW - Staphylococcus aureus KW - Skin and soft tissue infection (SSTI) KW - Antibiotic susceptibility pattern KW - MRSA N2 - Background: Staphylococcus aureus (S. aureus) is the most common cause of skin and soft tissue infections. This study aimed to determine the prevalence of S. aureus isolated from skin and soft tissue and antibiotic susceptibility pattern among the patient hospitalized in Razi skin hospital (Tehran-Iran). Materials and Methods: This cross-sectional study was conducted on patients (n=400) with skin and soft tissue infections in Razi skin hospital. Sterilized swabs were used to collect the skin infection samples. S. aureus isolates were confirmed using biochemical tests (gram staining, catalase, coagulase, DNase test and manitol fermentation tests). Result: 51.3 %( 205 out of 400) of isolates were S. aureus. Ninety six (46.8%) of isolates were methicillin and penicillin-resistant S. aureus. All of the isolates showed sensitivity to vancomycin, linezolid. 98% of the isolates were susceptible to daptomycin. One-hundred sixteen (56.6%) isolates were multi- drug resistant. Conclusion: More than half of the skin and soft tissue infections were caused by S.aureus. More than 46 percent of the isolates were methicillin resistant. The highest resistance to penicillin was observed. M3 ER -