TY - JOUR T1 - A study about the effect of ultrafiltration’s increasing on the clearance of middle molecules in Low-Flux Hemodialysis TT - بررسی تاثیر افزایش اولترافیلتراسیون بر کلیرانس مولکول‌های متوسط در همودیالیز با غشای low-flux JF - KAUMS JO - KAUMS VL - 10 IS - 3 UR - http://feyz.kaums.ac.ir/article-1-81-en.html Y1 - 2006 SP - 22 EP - 27 KW - Ultrfiltration KW - Middle molecules KW - Low-flux filters KW - Hemodialysis adequacy N2 - Background: Considering the importance of removal of these solutes in chronic renal failure patients, this study was carried out to evaluate the effect of increasing ultrafiltration on clearance of middle molecules in low-flux hemodialysis in Kashan, 2005.Materials and Methods: Twenty one hemodialysis patients, 11 women and 10 men, were enrolled to this clinical before-after study. At the first stage the patients were dialyzed with ultrafiltration equal to their dry body weight. At the second stage two liters was added to the ultrafiltration and clearance of each solute was calculated in both stages. Data were analyzed using SPSS software and square T test.Results: T here was a significant difference in clearance of ß2-microglobulin and vitamin B12 in second stage in comparison with the first one (p M3 ER -