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Showing 5 results for Creatine Kinase
Ali Zarghami-Khameneh , Afshar Jafari,
Volume 18, Issue 3 (6-2014)
Abstract
Background: Some scientific data have been reported the positive effects of caffeine compounds on modulating the signs of delayed onset muscle soreness. The present study was conducted to identify the effect of different doses of caffeine on some serum markers of muscular damage in male volleyball players after a single session of exhaustive exercise. Materials and Methods: In a randomized double-blind study, 30 male volleyball players (mean age 21.47±1.45 years, fat percent 10.47±3.11% and BMI 23.15±1.26 kg.m2) were allocated into three equal groups: the supplement (6 and 9 mg.kg-1 caffeine) and placebo (6 mg.kg-1 dextrose) groups. After the supplementation, all subjects were participated in a single session of resistant weight-training (80% until exhaustion). Changes in the muscular damage indices including total serum creatine kinase and lactate dehydrogenase were determined in three phases (baseline, immediately and 24 hours after the training). Results: The results showed that the different doses of caffeine had no significant effect on the increased levels of serum enzymes of muscular damage immediately after exercise compared to the placebo group (P≥0.05). Moreover, different doses of caffeine had no effect on the increased levels of muscle damage markers 24 hours after the exercise (P≥0.05). Conclusion: Although the different doses of caffeine cannot significantly prevent further muscular damage, it cannot lead to the further deterioration of indirect indices of muscle damage.
Reza Farzizade, Lotfali Bolboli, Akbar Abravesh, Babak Nakhostinrohi,
Volume 23, Issue 6 (12-2019)
Abstract
Background: One of the most common methods for assessing cardiac damage is the measurement of biological indicators related to heart tissue damage. This study aimed to compare the effects of two types of acute weight loss programs (2 and 4%) on the levels of creatine kinase and troponin enzymes in the elite wrestlers.
Materials and Methods: For this purpose, 16 young wrestlers (age: 18±1.31 years, weight: 71.68±13.17 kg, height: 171±6.40 cm) in the form of crossover were randomly divided into two groups with weight loss of 2 and 4% of body weight. Blood samples were analyzed in four stages: before, immediately, 6 hours and 24 hours after losing weight. Repeated measures ANOVA and Bonferroni post hoc test for evaluation of within groups variations, and independent T-test for comparison between groups were used.
Results: The results of this study showed that CK-MB was significantly increased in two groups after weight loss (P=0.009). However, within 24 hours after weight loss, the level of isoenzyme creatine kinase returned to the level of resting. Also, there was a significant increase in cTnI level in the two groups (P=0.004), this difference was more in the 2% than the 4% group, however, within 24 hours; weight loss was returned to resting levels.
Conclusion: Although the level of CK-MB and cTnI enzymes increased in two groups after rapid weight loss, but rapid weight loss of 2 and 4% of body weight cannot cause serious cardiac damage.
Yeganeh Hadavand-Mirzaii, Farah Nameni,
Volume 24, Issue 4 (8-2020)
Abstract
Background: The most common symptoms of serum muscle injury that may change after intense physical activity are creatine kinase and lactate dehydrogenase (CK, LDH). This study aimed to study the effects of TRX training course and central stability on CK and LDH in obese girls.
Materials and Methods: The research was semi-experimental. The subjects of this research, including 40 women from 20-25 years old, were randomly selected as research sample and were randomly assigned into 4 groups (10) (TRX, central stability, TRX-central stability and control). The subjects performed the program for 8 weeks. Before and after training period, blood samples were taken and evaluated. Kolmogorov-Smirnov, Leven, one-way ANOVA tests were used to determine (P≤0.05).
Results: The results of the present study showed that creatine kinase (P=0.002) and lactate dehydrogenase (P=0.001) were reduced in all three groups after the training period compared to before the exercise and this change was significant compared to the control group. However, no significant difference was observed between different training methods.
Conclusion: Performing all three resistance training methods of the whole body, central stability and combining these two methods together, caused damage, inflammation and muscle contraction but gradually the principle of adaptability was adjusted to the production of the enzymes creatine kinase and lactate dehydrogenase. All of the three methods can be recommended as methods to increase muscle strength.
Ali Ahmadzadeh, Ameneh Pourrahim-Ghouroghchi, Roghayeh Afroundeh,
Volume 25, Issue 1 (3-2021)
Abstract
Background: Curcumin supplementation consumption is effective in reducing muscle damage and inflammation sport performance. This study aimed to effect of eight weeks of curcumin supplementation consumption on muscle injury and inflammation following an acute session of strength activity in male futsal players.
Materials and Methods: Twenty male futsal players (age (year): 26.06±3.88 and BMI: 24.4±3.17) volunteered to participate in the study and were randomly assigned to supplementation and control groups. Blood sampling was performed in four stages. After the first blood sampling from both supplementation and control groups, one acute session of circular strength training in 5 stations and 3sets with 75%1RM were performed. The second blood sampling was performed. Forty-eight hours later, the experimental group used 150 mg curcumin supplementation tablet, 3 days a week during 8 weeks. Forty-eight hours after the last using, blood sampling was performed in both groups. Both supplementation and control groups performed the second acute circular strength training and one hour later, the fourth stage blood sampling was performed. Control group consumed placebo during 8 weeks. Data were analyzed using SPSS software version 25 using mixed analysis of variance.
Results: The results showed that 8 weeks curcumin supplementation consumption, significantly decreased creatine kinase, white blood cells, neutrophils and monocytes following acute second strength activity (P<0.05). However, Lymphocytes did not change significantly (P>0.05).
Conclusion: It seems that curcumin supplementation consumption can reduce exercise-induced muscle injury and inflammation in male futsal players. So, it is recommended that male futsal coaches and players use curcumin supplements to reduce muscle damage and inflammation after an acute strength activity.
Fatemeh Kazeminasab, Ali Bahrami Kerchi, Fatemeh Sharafifard, Nafiseh Hasanpour,
Volume 28, Issue 4 (6-2024)
Abstract
Background and Aim: Vitamin D has been shown to reduce exercise-induced muscle damage and muscle soreness; however, further research is needed to establish definitive conclusions. The aim of this study was to investigate the effect of vitamin D supplementation on muscle soreness and recovery after exercise.
Methods: A systematic review and meta-analysis was conducted to evaluate the effects of vitamin D intake on muscle soreness and biochemical markers of muscle damage, including myoglobin (MB), creatine kinase (CK), lactate dehydrogenase (LDH), and inflammatory factors such as TNFα and IL-6. Data were sourced from PubMed, Scopus, and Web of Science databases up to February 2024. Analyses were performed to compare vitamin D with placebo, and weighted mean differences (WMD) were calculated.
Results: A total of 11 studies involving 358 athletes and non-athletes were examined. Changes in muscle soreness immediately after exercise due to vitamin D intake were not statistically significant [P=0.70, WMD=-0.07]. However, vitamin D significantly reduced muscle soreness 24 hours after exercise [P=0.04, WMD=-0.40]. No significant changes were observed in CK [P=0.30, WMD=-3.22 U/L], LDH [P=0.30, WMD=-11.86 U/L], or MB [P=0.50, WMD=10.66 ng/ml] immediately after exercise.
Conclusion: Vitamin D may be effective in reducing muscle soreness 24 hours post-exercise, but it does not appear to significantly affect markers of muscle damage, including CK, MB, and LDH, in the timeframes studied. Further research in this area is recommended.
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