:: Volume 25, Issue 6 (Bimonthly 2021) ::
Feyz 2021, 25(6): 1314-1324 Back to browse issues page
The effect of diabetes mellitus on clinical, biochemical indications and mortality in patients with COVID-19; an analytical cross sectional study
Somaieh Karkhaneh , Alireza Abrishamib , Babak Gharaeic , Reza Vagheitabar , Mahsa Alborzi Avanaki , Fariba Samadian , Ali Zare , Leyla Karkhaneh *
Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran , l_karkhaneh@yahoo.com
Abstract:   (900 Views)
Background: Coronavirus infection in patients with pre-existing diabetes mellitus has been shown to indicate a poorer outcome compared to non-diabetic cases. This study aimed to explore disease severity and mortality in patients infected with Coronavirus 2019 disease (COVID-19) between these two groups.
Materials and Methods: The current analytical cross sectional study reviewed the medical records of 99 patients hospitalized with laboratory-confirmed COVID-19 from February 14th to February 26th, 2020. The cases were divided into non-diabetic (n=77) and diabetic (n=22) groups. The differences in clinical symptoms, biochemical parameters, length of hospital stay, CT scan analysis, and the proportion of the patients with the outcome of mortality were compared.
Results: The statistical analysis illustrated that most of the patients were male, and compared to non-diabetic, patients with diabetes were significantly older (P=0.01). Results indicated a considerable increase in ALP, vitamin D, pO2 levels of serum and a decrease in SpO2 (P<0.05). The patients with co-existing metabolic disorders, such as cardiovascular diseases were significantly higher in the diabetic group (P<0.05). Statistics evaluation did not show significant differences between the two groups in terms of other assessed factors and CT images.
Conclusion: Based on the current study, it seems that diabetic and non-diabetic patients have almost similar clinical and paraclinical findings, so additional investigations with larger sample sizes are needed to achieve more accurate results.
Keywords: Diabetes mellitus (DM), COVID-19, Mortality
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Type of Study: Review | Subject: medicine, paraclinic
Received: 2021/08/1 | Accepted: 2021/12/4 | Published: 2022/02/1

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Volume 25, Issue 6 (Bimonthly 2021) Back to browse issues page