[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 22, Issue 2 (Bimonthly 2018) ::
Feyz 2018, 22(2): 162-168 Back to browse issues page
Liver enzyme changes following the consumption of ginger and eccentric exercise in overweight girls
Halime Vahdatpoor , Said Shakeryan *
Department of Exercise Physiology, Shahid Chamran University of Ahvaz, I. R Iran. , sashakeryan@gmail.com
Abstract:   (3393 Views)
Background: The aim of this study was to examine the effect of two weeks ginger supplement on some liver enzymes including aspartate aminotransferase (AST), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) following eccentric activity in overweight girls.
Materials and Methods: In this semi-experimental study, 28 overweight female students were randomly divided into two complementary (n=14) and placebo (n=14) groups. The supplement group consumed 2 grams of ginger powder daily for two weeks. The exercise protocol consisted of two sessions of exhausting activity (negative slope on treadmill, one session before and one session after two weeks of supplementation) with an initial speed of 4 km/h and an initial gradient of 2%. Blood samples were measured in four stages before and immediately after the exercise in two steps before and after the use of ginger supplement to measure changes in liver enzymes.
Results: The results showed that eccentric activity increased the AST, ALP and ALT levels. Also, there was no significant difference in the AST, ALP and ALT levels between the supplement and placebo groups after two weeks of ginger supplementation (P≥0.05).
Conclusion: It seems that the use of ginger had a small effect in the improvement of liver enzyme serum levels. Therefore, the intensity and duration of the effective exercise, especially when consuming ginger, needs to be further investigated
Keywords: Eccentric exercise, Ginger, Liver enzymes, Overweight
Full-Text [PDF 276 kb]   (10818 Downloads)    
Type of Study: Research | Subject: General
Received: 2018/01/24 | Accepted: 2018/05/1 | Published: 2018/05/5
1. Gleeson M, Bishop NC, Stensel DJ, Lindley MR, Mastana SS, Nimmo MA. The anti-infla‌mm‌atory effects of exercise: mechanisms and imp‌lications for the prevention and treatment of disease. Nat Rev Immunol 2011; 11(9): 607-15.
2. Allen DG, Whitehead NP, Yeung EW. Mecha‌nisms of stretch-induced muscle damage in normal and dystrophic muscle: role of ionic changes. J Physiol 2005; 567: 723-35.
3. Wilmore JH, Costill DL. Physiology of Sport and Exercise. 3rd ed. Human Kinetics. Champaign; 2005. p.3.
4. Peterson JM, Terappe TA, Mylona E, White F, Lambert CP, Evans WJ, et al. Ibuprofen and acetaminophen: effect on muscle inflammation after eccentric exercise. Med Sci Sports Exerc 2003; 35: 892-6.
5. Noakes TD. Effect of exercise on serum enzyme activities in humans. Sports Med 1987; 4(4): 245-67.
6. Chang YC, Chuang LM. The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. Am J Transl Res 2010; 2(3): 316-3.
7. Battis Jr GN. The Enigma of Liver Enzymes: Transferases. J Insurance Med 1988; 20(2).
8. Lawlor DA, Sattar N, Smith GD, Ebrahim S. The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyl transferase. Am J Epidemiol 2005; 161(11): 1081-8.
9. Stockham SL, Scott MA. Fundamentals of veterinary clinical pathology: John Wiley & Sons; 2013.
10. Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, et al. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss.Gut 2011; 60(9): 1278-83.
11. Thoma C, Day CP, Trenell MI. Lifestyle inter‌ventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review. J Hepatol 2012; 56(1): 255-66.
12. Wilmor J, David El. Physiology of Exercise and Physical Activity. Translated by: Moeini Z, F Rahmaniennia F, Rajabi H, Aqaali Nejad H, Salami F, Volume I, Fourth Edition, Fourteenth Edition, Tehran: Innovators 2010; (3): 123-31.
13. Meganathan M. Evaluation of Hepatoprotective Effect of Omega 3-Fatty Acid against Paracetamol Induced Liver Injury in Albino Rats. Global J Pharmacol 2011; 5(1): 50-3.
14. Clarkson PM, Kearns AK, Rouzier O, Rubin R, Thampson PD. Serum creatine kinas levels and renal function measures in exertional muscle damage. Med Sci Sports Exerc 2006; 38(4): 623-7.
15. Jordan SL. The effects of green tea extract supplementation on delayed onset muscle soreness and oxidative stress [thesis]. USA. Texas Tech University. 2007.
16. Funk JL, Frye JB, Oyarzo JN, Chen J, Zhang H, Timmermann BN, et al. Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arth‌ritis. Pharma Nutrition 2016; 4(3): 123-31.
17. Black CD, Herring MP, Hurley DJ, O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pa‌in caused by eccentric exercise. J Pain 2010; 11(9): 894-903.
18. Praphatsorn P, Thong-Ngam D, Kulaputana O, Klaikeaw N. Effects of intense exercise on biochemical and histological changes in rat liver and pancreas. 2010.
19. Drotman RB, Lawhorn GT. Serum enzymes as indicators of chemically induced liver damage. Drug Chem Toxicol 1978; 1(2): 163-71.
20. Kratz A, Lewandrowski KB, Siegel AJ, Chun KY, Flood JG, Vancott EM, et al. Effect of mara‌thon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am J Clin Pathol 2002; 118(6): 856-63.
21. Keating SE, Hackett DA, George J, Johnson NA. Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis. J Hepatol 2012; 57(1): 157-66.
22. Kashif M, Bonyan A, Rad M, Effect of Creatine Supplement and Creatine-Carbohydrate Blend on Anaerobic Capacity and CK (LDH) Indicators in Male Athletes 18-15 Years Old. J Sport Sci 2012; 2(13): 125-52 [in Persian]
23. Shati AA, Elsaid FG. Effects of water extracts of thyme (Thymus vulgaris) and ginger (zingiber officinale Rosco) on alcohol absorb. Food Chem Toxicol 2009; 47(8): 1945-9.
24. Khoshvaghti A, Khoshnood M. Study of the Effect of Ginger Powder on Liver Biochemical, Renal and Pancreatic Indicators in Rat. J Clin Veterinary Clin Sci Iran 2014; (8): 1-1. [in Persian]
25. Abdel-Azeem AS, Hegazy AM, Ibrahim KS, Farrag AR, El-Sayed EM. Hepatoprotective, anti‌oxi‌dant, and ameliorative effects of ginger (Zin‌giber officinale Roscoe) and vitamin E in ace‌taminophen treated rats. J Diet Suppl 2013; 10(3): 195-209.
26. Shidfar F, Rajab A, Rahideh T, Khandouzi N, Hosseini S, Shidfar S, et al. The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes. J Complement Integr Med 2015; 12(2): 165-70.
27. Rahimlu M, Yari Z, Hekmat f Azita, Alavian Seyyed M, Farmer SA, et al. The Effect of Ginger Supplement on Liver Enzymes and Steatosis and Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver. J Nutrition Sci Food Technol Iran 2016; (2): 8- 1. [in Persian]
28. González-Ruiz K, Ramírez-Vélez R, Correa-Bautista JE, Peterson MD, García-Hermoso A. The Effects of Exercise on Abdominal Fat and Liver Enzymes in Pediatric Obesity: A Systematic Rev‌iew and Meta-Analysis. Child Obes 2017; 13(4): 272-82.
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Vahdatpoor H, Shakeryan S. Liver enzyme changes following the consumption of ginger and eccentric exercise in overweight girls. Feyz. 2018; 22 (2) :162-168
URL: http://feyz.kaums.ac.ir/article-1-3515-en.html

Volume 22, Issue 2 (Bimonthly 2018) Back to browse issues page
مجله علمی پژوهشی فیض ::: دانشگاه علوم پزشکی کاشان KAUMS Journal ( FEYZ )
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4311