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:: Volume 22, Issue 2 (Bimonthly 2018) ::
Feyz 2018, 22(2): 185-191 Back to browse issues page
The utility of Helicobacter pylori eradication in improving functional dyspepsia in adult population in Iran
Nastaran Maghbooli , Mohammad Ali Mohammadi , Mohammad Reza Naderian , Raika Jamali *
Students Scientific Research Center, Tehran University of Medical Sciences, Tehran, I. R. Iran. , raika.jamali@gmail.com
Abstract:   (2091 Views)
Background: This review aimed at investigating the effectiveness of Helicobacter pylori eradication in improving the symptoms of patients with functional dyspepsia in Iranian adult population.
Materials and Methods: This study was a systematic review. Data were collected from the Medline database by searching some keywords including "Helicobacter pylori", "eradication", "effectiveness", "dyspepsia", and "Iran". After obtaining the full text of articles, the critical review was performed based on article titles and abstracts. For each article, information regarding benefits, side effects and efficacy was identified. Then, scenarios were extracted according to the mentioned data.
Results: From a total of 28 reviewed papers, 6 were systematic reviews (with the level of evidence 1a), 18 articles were randomized interventional trials (with the level of evidence 1b) and 4 articles were longitudinal studies (with the level of evidence 2b). Most studies reported improvement in symptoms, although some of them did not report the statistically significant difference. After extracting data related to the scenarios from the articles, they were rated regarding the clinical advantage and the ability to localize each scenario.
Conclusion: Considering the results of analyzing the articles and extracted scenarios, Helicobacter pylori eradication is recommended in Iranian adult patients with functional dyspepsia, normal upper gastrointestinal endoscopy, and documented Helicobacter pylori infection.
Keywords: Helicobacter pylori, Functional dyspepsia, Iran
Full-Text [PDF 274 kb]   (1169 Downloads)    
Type of Study: Review | Subject: medicine, paraclinic
Received: 2018/01/10 | Accepted: 2018/03/28 | Published: 2018/03/28
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Maghbooli N, Mohammadi M A, Naderian M R, Jamali R. The utility of Helicobacter pylori eradication in improving functional dyspepsia in adult population in Iran. Feyz. 2018; 22 (2) :185-191
URL: http://feyz.kaums.ac.ir/article-1-3505-en.html

Volume 22, Issue 2 (Bimonthly 2018) Back to browse issues page
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