Background: This study was designed to evaluate the visual results of lensectomy and Anterior Chamber intraocular lens implantation in patients with Marfan syndrome and hereditary sublaxation of lens in Matini Hospital of Kashan-Iran from 2001-2006.

Materials and Methods: In an interventional case series, records of patients with hereditary sublaxation of lens with a surgical correction were reviewed. The criterion involved was low visual acuity (VA) due to uncorrectable refractive error. All patients were followed for at least 3 months. Data on age, sex, pre and post operative best corrected visual acuity (BCVA), Intraocular Pressure (IOP) and complications were recorded.

Results: The study group included 19 eyes of 11 patients with mean age of 34.7 years (range of 12 to 48 years). Sixty-three percent of patients were male. All patients were followed for at least 3 months with mean of 25 months (ranging 3-60 months). Pre operation mean of BCVA was <1/10 in 89% of eyes that improved to >3/10 in 82.5% post operatively (P<0.05). No visual-threatening complications such as glaucoma, hypotony or retinal detachment was observed in the studied subjects. The most common post operative complication was sterile uveitis (21.1%) which was treated successfully with medications.

Conclusion: Pars plana lensectomy with implantation of AC IOL and prophylactic band in Marfan patients with hereditary sublaxation of lens improves visual acuity without serious complications.