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:: Volume 19, Issue 3 (Bimonthly 2015) ::
Feyz 2015, 19(3): 204-213 Back to browse issues page
The effect of grape seed (Vitis vinifera L.) extract supplementation on lipid profile and high-sensitivity C-reactive protein levels after aerobic exercise in non-athlete males
Hamid Reza Zolfi, Vahid Sari-Sarraf *, Hosein Babaei, Ramin Amirsasan
University of Tabriz , sarraf@tabrizu.ac.ir
Abstract:   (6429 Views)

Background: There are a few studies about the positive effects of exercise and polyphenols supplementation on reduction of cardiovascular risk factors. Therefore, this study aimed to investigate the effect of short-term grape seed extract (GSE) supplementation on lipid profile and high-sensitivity C-reactive protein (hs-CRP) levels after an aerobic exercise in non-athlete men.

Materials and Methods: In a randomized double-blind study, 20 non-athlete men (age range, 19±1 years, body fat 12.20%±3%, body mass index 22.22±2, and VO2max 39.28±2 ml.kg-1.min-1) were allocated into two equal groups (n=10): the GSE supplementation (200 mg/day) and placebo groups. The hs-CRP, triglyceride (TG), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C) and total cholesterol (TC) levels were measured before and after the supplementation and after an aerobic exercise protocol with 75% VO2max on the motorized treadmill for 30 minutes.

Results: The results showed a significant reduction in TG and a significant increase in hs-CRP after the exercise in both groups (P<0.05). However, there was no significant difference between groups in HDL-C, LDL-C, and TC levels (P>0.05). In addition, there was a significant decrease in TC levels subsequent GSE supplementation (P<0.05).

Conclusion: A single session of aerobic exercise has no significant effect on lipid profiles except TG and can lead to an increase in the hs-CRP concentration. However, the short-term GSE supplementation can just improve the TC of lipid profile.

Keywords: Grape seed extract, Aerobic exercise, hs-CRP, Triglyceride, Low-density lipoprotein, High-density lipoprotein, Cholesterol
Full-Text [PDF 274 kb]   (2492 Downloads)    
Type of Study: Research | Subject: medicine, paraclinic
Received: 2015/07/15 | Accepted: 2015/07/15 | Published: 2015/07/15
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Zolfi H R, Sari-Sarraf V, Babaei H, Amirsasan R. The effect of grape seed (Vitis vinifera L.) extract supplementation on lipid profile and high-sensitivity C-reactive protein levels after aerobic exercise in non-athlete males. Feyz. 2015; 19 (3) :204-213
URL: http://feyz.kaums.ac.ir/article-1-2709-en.html


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Volume 19, Issue 3 (Bimonthly 2015) Back to browse issues page
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