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:: Volume 16, Issue 7 (Supplement 2013) ::
Feyz 2013, 16(7): 715-716 Back to browse issues page
Effect of Florid on the metabolism of serum Iron-related parameters in rat
Minoo Moshtaghie , Elham Moshtaghie , Jahanshah Mahdavi , Hosein Pourmoghadas
Islamic Azad University , m_moshtaghie@yahoo.com
Abstract:   (5102 Views)

Background: Nowadays the extra amounts of some elements above the standard level can affect the human health among them are Florid that is used in toothpaste. The aim of this study was to study the effect of Florid on Iron metabolism in rat for short and long terms.

Materials and Methods: Florid (100, 200 and 300 ppm) was added to the rat drinking water. One control group is also selected with no florid in the drinking water. This study was undertaken in different time periods (5-88 days). After the decapitation, blood samples were collected for further experiments. Some parameters related to Iron metabolism were measured using laboratory standard methods.

Results: Results indicate that, in short term, no significant difference was seen between the control and experimental groups. In the second time period (22 days), a significant difference was seen between the control and other groups. Finally, in the third group (44 and 88 days Florid) the decreasing of hematocrit level up to 10-12 percent was obtained. Elevation in serum TIBC and reduction in serum iron and also copper was seen.

Conclusion: It is concluded that the extra consumption of Florid in toothpaste may cause damage to iron related parameters when it used for long period of time.

Keywords: Florid, Iron, Metabolism, TIBC
Full-Text [PDF 85 kb]   (1243 Downloads)    
Type of Study: Research | Subject: General
Received: 2013/03/3 | Published: 2013/03/15
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Moshtaghie M, Moshtaghie E, Mahdavi J, Pourmoghadas H. Effect of Florid on the metabolism of serum Iron-related parameters in rat . Feyz 2013; 16 (7) :715-716
URL: http://feyz.kaums.ac.ir/article-1-1824-en.html


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This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
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Volume 16, Issue 7 (Supplement 2013) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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