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:: Volume 15, Issue 1 (Quarterly 2011) ::
Feyz 2011, 15(1): 21-26 Back to browse issues page
A comparison between touch cytology and histology method in diagnosing Helicobacter pylori infection
Raika Jamali , Hosain Sharifi , Tahereh Mazoochi , Tahereh Khamechian , Sayyed Mohammad Matini
Kashan University of Medical Sciences , drj1351@yahoo.com
Abstract:   (8448 Views)

Background: Touch cytology is one of the sensitive ways of diagnosing Helicobacter pylori in stomach biopsies. The current study was designed to compare touch cytology with histology method in the diagnosis of Helicobacter pylori infection.

Materials and Methods: This study was performed on 150 dyspeptic patients undergoing upper gastrointestinal endoscopy in Kashan Shahid Beheshti Hospital. Antrum samples (2-4) were taken from each of 150 patients. One biopsy sample was considered for touch cytology and the remaining biopsy samples were studied for histological examination.

Results: Eighty-three out of 150 patients (55.3%) were men with the mean age of 46.63±5.93 years. The sensitivity, specificity, positive predictive value and negative predictive value in the touch cytology method were 95.65%, 100%, 100% and 66%, respectively, while in the histology method they were 84.78%, 100%, 100% and 36.36%, respectively. The sensitivity of the touch cytology was more than that of the histology method (P<0.001) in the diagnosis of H. pylori.

Conclusion: Since the cytology method is more sensitive with equal specificities in relation to histology method, when the histological information is not necessary, the cytology method can be considered more reliable for diagnosing Helicobacter pylori.

Keywords: Cytology, Helicobacter pylori, Histology, Sensitivity and specificity
Full-Text [PDF 228 kb]   (2174 Downloads)    
Type of Study: Research | Subject: General
Received: 2011/03/29 | Revised: 2011/04/9 | Published: 2011/04/15
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Jamali R, Sharifi H, Mazoochi T, Khamechian T, Matini S M. A comparison between touch cytology and histology method in diagnosing Helicobacter pylori infection . Feyz 2011; 15 (1) :21-26
URL: http://feyz.kaums.ac.ir/article-1-1102-en.html


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This open access journal is licensed under a Creative Commons Attribution-NonCommercial ۴.۰ International License. CC BY-NC ۴. Design and publishing by Kashan University of Medical Sciences.
Copyright ۲۰۲۳© Feyz Medical Sciences Journal. All rights reserved.
Volume 15, Issue 1 (Quarterly 2011) Back to browse issues page
مجله علوم پزشکی فیض Feyz Medical Sciences Journal
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