2024-03-28T20:31:35+03:30 http://feyz.kaums.ac.ir/browse.php?mag_id=77&slc_lang=fa&sid=1
77-2101 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Effect of fluoxetine on hormonal axis of pituitary-gonad in adult female rats Anahita Ebrahimian Vahid Hemayatkhah-Jahromi Dr.hemayatkhah@yahoo.com Mohsen Forouzanfar Background: Fluoxetine is frequently used to treat depression. There has not been any report for the effect of fluoxetine on hormonal axis of pituitary-gonad in rats. Several studies have also shown that antidepressants have interaction with sex hormones in both sexes and women are more likely to take antidepressants than men. This study aimed to examine the effect of fluoxetine on sexual hormones in female rats. Materials and Methods: In this experimental study, 40 female rats (180-200 g and 100-120 days of age) were divided into the five groups including control, sham and three experimental (fluoxetine 5, 10 and 20 mg/kg) groups. Fluoxetine was intraperitoneally injected during four weeks. Control group did not receive any drug, but the sham group was injected with distilled water (0.18-0.2 ml/kg body weight). Levels of FSH, LH, estrogen and progesterone were measured using a blood test. Results: Results of this study showed that fluoxetine (10 or 20mg/kg) considerably reduced the estrogen and FSH levels and also fluoxetine (20mg/kg) reduced the progesterone level. However, different doses of fluoxetine did not change the LH level. Conclusion: Fluoxetine can decrease the estrogen, progesterone, FSH levels and cause oogenic defects in rats. Fluoxetine Rat Estrogen Progestrone LH FSH 2014 1 01 517 521 http://feyz.kaums.ac.ir/article-1-2101-en.pdf
77-2102 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Role of endogenous opioids in nociception among male and different phases of the mice estrous cycle Mahnaz Kesmati m.kesmati@scu.ac.ir Sedigheh Abbasi Mozhgan Torabi Background: Sexual hormones can change nociception in males and females. There are few information about the role of sex hormones on nociception. The aim of this study was to evaluate the effect of endogenous opioids on nociception in male mice compared with female mice during different phases of the estrous cycle (proestrus, estrus, metestrus and diestrus).Materials and Methods: In this study, adult male and female mice (in different phases of estrous cycle (weighing 30±3gr were assigned to the control group, vehicle and naloxone (3mg/kg, i.p.) groups. In all groups analgesia time was evaluated by hotplate test. Results: Analgesia time in diestrus phase of control and vehicle groups of female rats was more than the other phases and different from the estrus phase (P<0.05) and male (P<0.001) groups. In the naloxone group, there was a significant reduction in analgesia time among males (P<0.001) and also in the proestrus, estrus, metestrus, diestrus phases (P<0.001, P<0.05, P<0.001, P<0.001, respectively) among females. Moreover, in the naloxone group, a significant difference was seen in analgesia time in male mice compared with females in proestrus and diestrus phases (P<0.05). Conclusion: It seems that the effects of sex hormones in male and female mice on pain perception mechanisms can be mediated by endogenous opioids. Hot plate test Pain Opioidergic system Estrus cycle Mouse 2014 1 01 522 527 http://feyz.kaums.ac.ir/article-1-2102-en.pdf
77-2103 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Antinociceptive effect of hydroalcoholic extract of green tea in male mice Naghmeh Ahmadian-Baghbadorani Hasan Azhdari-Zarmehri hasan.azhdari@gmail.com Sina Puzesh Faezeh Sadat Mousavi Farzad Rajaei Background: The use of medicinal plants due to their lower side effects and the various efficient components has been increased in recent years. The aim of this study was to evaluate the antinociceptive effect of hydroalcoholic extract of green tea in male mice using the hot plate and formalin tests. Materials and Methods: In this experimental study, 56 NMRI male mice (weight, 28±3 g) were assigned to the control and experimental groups. The experimental group received the green tea extract (75, 150 and 300 mg/kg) and 30 min after the injection, the hot plate and formalin tests were used to assess the acute and chronic pain. Results: Results showed that hydroalcoholic extract of green tea (75mg/kg) could induce antinociception in phase 2, not in phase 1 and interphase of the formalin test. Hydroalcoholic extract of green tea (150 and 300 mg/kg) could also induce antinociception in phase 1, interphase and phase 2 of the formalin test. Moreover, hydroalcoholic extract of green tea caused a delay on the painful behaviors in hot-plate test. Conclusion: Hydroalcoholic extract of green tea has analgesic properties and can be used as a substitute for chemical analgesic drugs. Hydroalcoholic extract Green tea Formalin test Hot plate test Male mice 2014 1 01 528 536 http://feyz.kaums.ac.ir/article-1-2103-en.pdf
77-2104 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Comparing the in vitro antifungal activity of various Aloe vera leaf extracts on Aspergillus flavus growth and aflatoxin B1 production Arash Babaei arash_babaei@yahoo.com Hadis Tavafi Milad Manafi Ameneh Fahimifar Background: Due to the wide spread of Aspergillus flavus contamination on the food stuff, its complete growth inhibition is inevitable. Aloe vera has anti-microbial compounds that have significant antifungal and antibacterial activities. The aim of this study was to compare the antifungal activity of acetonic, ethanolic and aqueous extracts of Aloe vera on A. flavus growth and aflatoxin B1 production. Materials and Methods: In this study, the antifungal activity of acetonic, ethanolic, and aqueous extracts of Aloe vera was evaluated using the agar plate diffusion method. Extracts were tested at different concentrations (0, 102, 103, 104 and 105 microliters /liter). To evaluate the effect of the extract on aflatoxin B1 production, the acetonic extract of Aloe vera was used and the amount of toxin produced was measured using the HPLC method. Results: The maximum antifungal activity (100%) was observed in 105 microliters /liter of acetonic extract. The inhibition percentages of aflatoxin B1 production at 2,000 and 2 microlitters /liter concentrations in 50 ml of culture medium were 40.94% and 18.14%, respectively. Conclusion: The acetonic extract of Aloe vera can be more effective than the other solvents to prevent A. flavus growth and it can also reduce the production of aflatoxin B1by A. flavus. Aspergillus flavus Aflatoxin B1 Antifungal activity Aloe vera HPLC 2014 1 01 537 544 http://feyz.kaums.ac.ir/article-1-2104-en.pdf
77-2106 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Comparing the effect of low-power laser therapy with methylprednisolone injection in unilateral plantar fasciitis Batol Zamani batol_zamani2007@yahoo.com Mehdi Hadizadeh-Moghdam Sayyed Alireza Moravveji Background: Plantar fasciitis accounts for 11 to 15 percent of foot pain in adults. Although an injection of corticosteroids is a common treatment in plantar fasciitis, it has side effects and short-term pain relief. Therefore, this study aimed to compare the effect of low-power laser therapy (LPLT) with methylprednisolone injection in unilateral plantar fasciitis patients.Materials and Methods: In this clinical trial study, 40 patients with unilateral plantar fasciitis were randomly allocated into two groups (n=20). In the first group, 40 mg of prednisolone was locally injected and the second group received LPLT in 10 sessions. Levels of pain and morning stiffness were evaluated.Results: Forty-two percent of cases were male and 57.5% female. Fifty-five percent of the patients had right and 45% had left foot fasciitis. The mean age of the patients was 52.98 years and the disease duration was 32.38 weeks. In men pain was seen more in the right foot and in women in left foot. Duration of pain in women with plantar fasciitis was more than the men. The effect of the two therapies on morning stiffness and pain reduction was the same in both groups. Moreover, pain reduction measured by visual analogue scale had a similar effect during the study in both groups. Conclusion: LPLT like corticosteroid injection has significant effect on the intensity and duration of pain and morning stiffness in plantar fasciitis and can be used as an alternative to corticosteroid injection. Plantar fasciitis Low-power laser Local corticosteroid injection 2014 1 01 545 552 http://feyz.kaums.ac.ir/article-1-2106-en.pdf
77-2107 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Effect of 8-week omega-3 supplementation on pulmonary function during classic army ranger training Vahid Sobhani Behzad Hajizadeh Behzad Bazgir Bazgirbehzad@yahoo.com Maryam Kazemipour Alireza Shamsoddini Abolfazl Shakibaey Background: Omega (ω)-3 fatty acids have positive effects on different body systems such as cardiovascular, respiratory, nervous, and skeletal systems. The purpose of this study was to examine the effect of ω-3 supplementation on pulmonary function in cadets participated in army ranger training. Materials and Methods: In this study, 41 army cadets (mean age, 18.6±‌0.9 years) were randomly allocated to the supplement (S, n=21) and placebo (P, n=20) groups. The two groups participated in army classic military training 4-5 days/week for 8 consecutive weeks. The S and P groups were asked to consume 1000 mg/day ω-3 and placebo per day for 8 weeks, respectively. Pulmonary function was assessed at the first and end of the training. Results: Results indicated a significant difference in FEV1, FVC, MVV, FEF25-75%, FIV1 at the end of the training compared to those obtained at the beginning in both groups however, the changes were markedly greater in the S group (P≤0.05). Conclusion: It can be concluded that the supplementation of ω-3 (1000 mg/d) can induce positive alteration in different pulmonary function indices. Pulmonary function Polyunsaturated omega-3 fatty acids Classic army ranger training 2014 1 01 553 560 http://feyz.kaums.ac.ir/article-1-2107-en.pdf
77-2108 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Early outcome of peripherally inserted central catheter versus peripheral IV line in very low birth weight neonates Mohammad Bagher Hosseini Behzad Jodeiri Majid Mahallei Shahram Abdoli-Oskooi Ahmad Safari hovaalim@yahoo.com Zakieh Salimi Background: Long-term hospitalization of preterm neonates and maintaining a secure intravenous line for them to provide nutrition and drugs are serious problems among some specialists. The purpose of this study was to compare the two types of IV access: peripherally inserted central catheter (PICC) and conventional peripheral IV line. Materials and Methods: In this randomized clinical trial, 117 preterm neonates with birth weight less than 1500 g were divided into the PICC line (57 cases) and peripheral IV line (60 cases) groups. The early outcomes including the duration of catheterization, catheter-related infection, and mortality rate of the neonates were compared for both groups.Results: The mean birth weights in the PICC and peripheral IV groups were 1061±183g and 1054±217 g, respectively (P=0.7). Sepsis with positive blood culture was reported in 8 cases in the PICC group and 7 cases in the peripheral IV group (P=0.9). Moreover, 7cases with a positive catheter tip culture (colonization) were found in the PICC group. Mortality rates in the PICC and peripheral IV line groups were 6 and 5, respectively (P=0.9). Conclusion: According to the results of this study, PICC does not increase the risk of sepsis and mortality rate in the neonates. Considering many advantages of the PICC line including its durability, it can be recommended for very low birth weight neonates. Neonates Peripherally inserted central catheter Peripheral IV line 2014 1 01 561 567 http://feyz.kaums.ac.ir/article-1-2108-en.pdf
77-2109 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Feasibility of formaldehyde removal from aqueous solutions by advanced oxidation process (UV/H2O2) Omolbanin Hasanbeiki Mohammad Bagher Miranzadeh miranzadeh_mb@kaums.ac.ir Gholam Reza Mostafaei DavarKhah Rabbani Hasan Akbari Background: Formaldehyde is usually used as a raw material in many industrial processes. High levels of formaldehyde may be found in effluent of the industries. Formaldehyde appears to have the potential for DNA damage, cell mutagenicity and carcinogenicity. This study aimed to investigate the feasibility of formaldehyde removal from aqueous solutions by advanced oxidation process (UV/H2O2). Materials and Methods: This bench-scale experimental study was conducted on aqueous solution containing 5000 mg/L of formaldehyde at the Pyrex reactor (16 cm width, 16 cm length and 26 cm depth). Experiments were conducted at two stages. First, the optimum pH and H2O2 concentration were determined. Then, the effect of the radiation was studied. Results: The rates of formaldehyde removal (pH=3 and 60 minutes reaction time) at different concentrations of H2O2 (0.4, 0.5, 0.6 and 0.7 mol/L) were 47%, 70%, 61% and 62%, respectively. Conclusion: UV/H2O2 can be used as an efficient process in removing high levels of formaldehyde. The optimum process conditions were: pH=3, a reaction time of 60 minutes and H2O2concentration of 0.5 mol/L. Formaldehyde Advanced oxidation process UV/H2O2 Hydrogen peroxide 2014 1 01 568 574 http://feyz.kaums.ac.ir/article-1-2109-en.pdf
77-2110 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Evaluating the agreement between the three screening instruments for mental disorder among students of Kashan University of Medical Sciences during 2011-2012 Hosein Akbari Hjat Zeraati zeraatih@tums.ac.ir Kazem Mohammad Mahmood Mahmoodi-Farahani Abdollah Omidi Background: One of the most important topics in clinical psychology is finding and measuring of independent tools that have the same results for the evaluation of a psychological characteristic. There are only few studies that have examined the agreement between these methods. This study aimed to compare the three screening instruments for mental disorder among students of Kashan University of Medical Sciences during 2011-2012. Materials and Methods: In this cross-sectional study, 983 students of Kashan University of Medical Sciences were selected using simple random sampling during 2011-2012. Students were asked to complete three mental health questionnaires including GHQ-28, BSI and MMPI. Data were analyzed using SPSS software.Results: Findings showed that the prevalence rates for mental disorder based on the GHQ-28, BSI and MMPI questionnaires were 39.1%, 44.8%, and 44%, respectively. Correlation coefficients for GHQ-28 with BSI, GHQ-28 with MMPI and BSI with MMPI were 0.588, 0.488, and 0.533, respectively. The corrected classification of GHQ‌28 with BSI was 73.3%, GHQ‌28 with MMPI 71.5% and MMPI with BSI 69.8%. Kappa coefficient showed high level of agreement between the three tests.Conclusion: According to the results of the study, there is a relatively high correlation between the three instruments in diagnosis of mental disorder among the students. GHQ BSI MMPI Mental health Students 2014 1 01 575 581 http://feyz.kaums.ac.ir/article-1-2110-en.pdf
77-2111 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Involvement of dorsal hippocampal beta-1 noradrenergic receptors in memory retrieval of rats Kowsar Fathinia Lotfollah Khajehpour khajehpour@scu.ac.ir Ahmad Ali Moazedi Sara Bemani-Lirgeshasi Background: Central beta-noradrenergic system plays an important role in the learning and memory processes. Dorsal hippocampus also has an overlapped distribution of beta-noradrenergic receptors. The aim of this study was to evaluate the possible role of the dorsal hippocampal beta-1 noradrenergic receptors in memory retrieval using a passive avoidance learning task. Materials and Methods: This experimental study was performed on adult male Wistar rats (weight, 230±20gr). After anaesthetizing, the rats were cannulated into dorsal hippocampus using the stereotaxic surgery. After one week, passive avoidance memory was studied in two phases: training and testing with a 24h interval. The step-through latency to enter dark compartment and the time spent in this compartment was recorded for the evaluation of memory. All animals received drugs or saline, as intra- dorsal hippocampal microinjection, 30 min before testing. Results: Pre-testing administration of dobutamine (1 μg/rat), a beta-1 noradrenergic receptor agonist, potentiated passive avoidance memory retrieval, while pre-testing injection of betaxolol (0.5μg/rat), a beta-1 noradrenergic receptor antagonist, inhibited passive avoidance memory retrieval. Also, the injection of ineffective and low doses of betaxolol (0.125 and 0.25 μg/rat) inhibited the effect of dobutamine on the memory retrieval. Conclusion: It seems that beta-1 noradrenergic receptors of the dorsal hippocampus may mediate memory retrieval in a passive avoidance learning model. Beta-1 adrenergic receptors Hippocampus Memory 2014 1 01 582 589 http://feyz.kaums.ac.ir/article-1-2111-en.pdf
77-2112 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Detection of cyfluthrin resistance mechanisms among German cockroach strains in vivo in Kashan during 2011-2012 Abbas Doroudgar Azim Paksa a.paksa@yahoo.com Hasan Vatandoost Alireza Sanei-Dehkordi Yaser Salim-Abadi Background: Development of insecticide resistance is a serious problem in the control of German cockroach population in home and hospital. Knowledge about the resistance mechanisms would help us to control the pest. This study was conducted to determine the cyfluthrin resistance in German cockroaches using the piperonyl butoxide (PBO). Materials and Methods: In this study, cyfluthrin (4-6 concentration ranges) was used on susceptible strains- for ten years without any contact with the lab-grown poison - with the mortality rate ranged from 0% to 100%. After determining the concentrations of the cyfluthrin in the susceptible strains, the level of susceptibility and resistance mechanism in the wild strains were determined using PBO in vivo. Data were analyzed using Probit program. Results: Lethal dose (LD50) and resistance ratio (RR) for susceptible and three wild strains were 133.43-503.6 and 1.48-3.77, respectively. LD50 of cyfluthrin+PBO and synergist ratio for susceptible and three wild strains were 51.3-490.53 and 1.03-2.43, respectively. Conclusion: All three collected strains showed different levels of resistance compared to the susceptible strains. In almost all strains, PBO considerably increases the cyfluthrin toxicity. The findings signify the involvement of monooxygenase in cyfluthrin resistance. German cockroach Resistance mechanism Piperonyl butoxide Cyfluthrin 2014 1 01 590 596 http://feyz.kaums.ac.ir/article-1-2112-en.pdf
77-2115 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Evaluating the prevalence of pneumococcal nasopharyngeal carriers and the related risk factors among students in Kashan Hamed Mirzaee Rezvan Moniri moniri@kaums.ac.ir Ahmad Piroozmand Mahdi Valipour Maryam Rezaei Maryam Yasini Sayyed Gholam Abbas Mousavi Background: Streptococcus pneumoniae, as an important human pathogen, is a leading cause of serious infections (e.g., sepsis, pneumonia and meningitis). Nasopharyngeal colonization is often the first step in the development of pneumococcal infections. The aim of this study was to determine the prevalence of S. pneumoniae serotypes in the nasopharynx of students in Kashan and its related risk factors. Materials and Methods: This cross-sectional study was conducted on 1289 students in Kashan from November 2011 to December 2012. Demographic and clinical data were collected from patients using a questionnaire. Samples were cultured on a selective media. Moreover, S. pneumoniae strains were identified using gram staining, detecting alpha hemolysis, catalase, optochin susceptibility and bile solubility tests. Results: One-hundred eighty one out of 1289 (14%) students were carriers for nasopharyngeal S. pneumoniae. There was a significant correlation between sex, age, previous respiratory infections, asthma, runny nose and previous hospitalization with an increased rate of the pneumococcal carriers. Conclusion: According to the high prevalence of pneumococcal carriers and a significant correlation between increased rates of colonization and sex, age, previous respiratory infections, asthma, runny nose and previous hospitalization, applying preventive strategies such as student vaccination seems to be necessary. Streptococcus pneumoniae Nasopharyngeal carriers Students 2014 1 01 597 601 http://feyz.kaums.ac.ir/article-1-2115-en.pdf
77-2113 2024-03-28 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2014 17 6 Vitamin D deficiency and related factors among the elderly with CHF Zohreh Taraghi Ehtram Sadat Ilaili Eilali@mazums.ac.ir Tahereh Yaghoobi Soheil Azizi Ahmad Ali Akbari- Kamrani Mahshid Foroughan Reza Fadaye-Vatan Robab Sahaf Razyeh Mokhtarpoor Nafiseh Ghanei Background: This study was designed to identify vitamin D deficiency and its related factors among the elderly with CHF. Materials and Methods: In this cross-sectional study, 50 elderly patients (26 women and 24 men) hospitalized with CHF and 50 elderly without CHF were randomly selected. The two groups were matched for age and sex and those who had taken vitamin D in the last six months were excluded from the study. Data were collected using a questionnaire which its content validity and reliability were confirmed. The level of 25- hydroxy vitamin D was measured using the ELIZA method.Results: The mean vitamin D levels in elderly with and without CHF were 33.76±2.82 and 41.76±3.06, respectively and there was no significant difference in vitamin D levels between the two groups. Among patients with vitamin D deficiency, weight gain (P=0.031), intestinal (P=0.022) and renal problems (P=0.031), in CHF patients were more than those without CHF. Conclusion: Considering the high prevalence of vitamin D deficiency among the elderly with CHF, it is necessary to monitor the vitamin D level in these patients. Vitamin D deficiency Heart failure Elderly 2014 1 01 602 609 http://feyz.kaums.ac.ir/article-1-2113-en.pdf