2024-03-29T08:19:16+03:30 http://feyz.kaums.ac.ir/browse.php?mag_id=64&slc_lang=fa&sid=1
64-1312 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Effect of lithium on neuropathic pain induced by partial ligation of rat sciatic nerve Hamidreza Banafshe Azam Mesdaghinia Mahdi Honarkar-Ramezani Meisam Noorani-Arani Sayyed Mojtaba Banitaba-Bidgoli Gholam Ali Hamidi hamidi_gh@kaums.ac.ir Background: Neuropathic pain is a type of chronic pain resulting from injury to the peripheral or central nervous system. Moreover, lithium is the main medication used to treat bipolar (manic-depression) disorder and some recent studies have also confirmed the neuroprotective effects of lithium. Considering the most common cause of neuropathic pain, nerve injury, the present study was designed to evaluate the effect of lithium on neuropathic pain induced by partial ligation of sciatic nerve in rat. Materials and Methods: This experimental study was conducted on 40 adult male rats. Neuropathic pain was induced by a partial sciatic nerve ligation model and animals were randomly divided into five groups: a control group that underwent the surgical procedure without sciatic nerve ligation and four experimental groups which received normal saline and different doses of lithium (5, 10 and 15 mg/kg, i.p.). Heat hyperalgesia, mechanical and cold allodynia were assessed at 3, 5, 7, 10 and 14 days after surgery.Results: According to the results, lithium (5, 10 and 15 mg/kg) significantly reduced heat hyperalgesia and cold allodynia induced by partial sciatic nerve ligation (P<0.01), while it reduced mechanical allodynia only at high doses (10 and 15 mg/kg). Conclusion: Lithium has an analgesic effect on neuropathic pain induced by partial ligation of sciatic nerve in rat. Further investigations would be needed to confirm the analgesic effect of lithium and its mechanisms of action in neuropathic pain. Lithium Allodynia Hyperalgesia Rat 2011 12 01 294 301 http://feyz.kaums.ac.ir/article-1-1312-en.pdf
64-1282 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Effect of hydro-alcoholic extract of Salvia officinalis on memory impaired by post-training administration of morphine using a passive avoidance paradigm in rat Asyeh Alizadeh-Makondi aciehalizadeh@yahoo.com Lotfallah Khajeh-Pour Mahnaz Kasmati Background: Studies have shown that the morphine can affect several neurotransmitter systems in the brain and impair memory retrieval. Moreover, it has been reported that the hydroalcoholic extract of Salvia officinalis can potentiate memory retention. Therefore, this study was conducted to evaluate the effect of hydroalcoholic extract of Salvia officinalis on memory impaired by post-training administration of morphine using a passive avoidance paradigm in rat. Materials and Methods: In this study, rats (220-250g) were trained in a step–through type passive avoidance task (1.5 mA shock for 3 seconds). Immediately after training, the animals received systemic injections of morphine (2.5, 5 and 7.5 mg/kg, s.c.) or Salvia officinalis (20, 40 and 60 mg/kg, s.c.). Another group received Salvia officinalis (20 mg/kg, s.c.) before training and morphine (7.5 mg/kg, s.c.) after training. All animals were tested 24 h after training to measure the step-through latency. Results: Findings indicated that post-training subcutaneous administration of morphine (5 and 7.5 mg/kg, s.c.) and Salvia officinalis (40 and 60 mg/kg, s.c.) impaired and enhanced memory retrieval, respectively in animals on the test day. Moreover, a systemic injection of Salvia officinalis (20 mg/kg, s.c.) before training restored the memory impairment induced by post-training morphine (7.5 mg/kg, s.c.). Conclusion: It seems that hydroalcoholic extract of Salvia officinalis can prevent the morphine-induced impairment of memory functions. Salvia officinalis Morphine Neurotransmitter Rat 2011 12 01 302 309 http://feyz.kaums.ac.ir/article-1-1282-en.pdf
64-1322 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Comparing the effects of apraclonidine versus timolol in preventing the intraocular pressure elevation after YAG laser capsulotomy Hasan Faraji-Pour farajipoor_h@kaums.ac.ir Fatemeh Atoof Mohammad Modayemzade Mohammad Reza Zahedi Background: Considering the high number of cataract surgery and the posterior capsular opacity as its complication which needs laser capsulotomy and also the rising of intraocular pressure (IOP) after such surgeries, the purpose of this study was to evaluate and compare the effects of apraclonidine and timolol separately in decreasing IOP after laser capsulotomy in Matini hospital of Kashan during 2010-11. Materials and Methods: In this clinical trial study, 200 eyes of patients with posterior capsular opacity were randomly divided into two groups and each group treated by timolol or apraclonidine before YAG laser capsulotomy. Then, the tonometer was used to record the intraocular pressure, 1 hour before, 6 and 24 hours after the capsulotomy.Results: One-hundred forty (70%) of the patients were women and 60 (30%) men. The interaction between the two drugs and time was not significant (P=0.104). There was no significant difference between the two groups for mean IOP at any time. (P=0.738). Therefore, apraclonidine and timolol are similar in their effects on reducing IOP after laser capsulotomy. In addition, mean IOP in three consecutive measurements were significantly different (P=0.001). Moreover, the differences between paired comparisons of time were also significant in all three measurements. Conclusion: The efficacy of apraclonidine in reducing IOP in patients underwent the posterior capsulotomy is established and it is similar to timolol in mechanism. Apraclonidine Intraocular pressure Posterior capsulotomy Timolol 2011 12 01 310 315 http://feyz.kaums.ac.ir/article-1-1322-en.pdf
64-1327 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Effect of an 8-week resistance training program on acetylcholinesterase activity in rat muscle Abdol Ali Banaeifar alibanaeifar@yahoo.com Ali Gorzi Mahdi Hedayati Zeynab Nabiollahi Neda Rahmani Moghaddam Mina Khantan Background: The neurophysiological mechanism for increasing strength by resistance training has not been understood precisely. The purpose of this study was to examine the effect of 8 weeks resistance training (RT) on A12 acetylcholinesterase (AChE) activity in rat muscle. Materials and Methods: In this experimental study, 16 male rats were randomly assigned into two groups: resistance training and control. The 8 weeks (5 sessions/week) resistance training consisted of climbing (3 sets of 4 repeats with a 3 min rest between the sets) a ladder (1 meter height consisted of 26 stairs) carrying a weight 30% of their body weight (suspended from the tail) in the first week and increased to 200% of body weight in the last week. Forty-eight hours after the last training session, the flexor hallucis longus (FHL) muscles of animals were isolated from the posterior lateral side of hindlimb under sterile conditions. Finally, AChE activity was measured for both groups. Results: No significant difference was seen in AChE activity in FHL muscles of the RT group (resistance: 1.31±0.48 vs. control: 1.01±0.29, P= 0.226).Conclusion: It seems that resistance training can not significantly increase AChE activity, as an acetylcholine release marker. Resistance training A12 acetylcholinesterase Flexor hallucis longus 2011 12 01 316 321 http://feyz.kaums.ac.ir/article-1-1327-en.pdf
64-1310 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Expression of nestin and nerve growth factors in adipose-derived mesenchymal stem cells Mohammad Taghi Ghorbanian ghorbanian@du.ac.ir Maryam Haji-Ghasem-Kashani Leili Hossein-Pour Leila Mirzaiyan Background: Adipose tissue represents an accessible source of mesenchymal stem cells (Adipose tissue derived mesenchymal stem cells-ADSCs). ADSCs could be differentiated into various mesenchymal stem cells (e.g. chondrocytes, adipocytes, osteoblasts, and neuronal lineages). Neurotrophic factors are diffusible polypeptides that have a critical role in survival, proliferation and differentiation of stem cells. This study aimed to evaluate the proliferative capacity and the expression of some neurotrophic factors such as brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), glial cell-derived neurotrophic factor (GDNF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4), nerve growth factor (NGF) and the expression of nestin in ADSCs. Materials and Methods: Rat ADSCs were isolated from the subcutaneous adipose tissue using mechanical and enzymatic digestion. These cells were cultured in αMEM supplemented with 10% fetal bovine serum. ADSCs of the third passage were evaluated by immunocytochemistry to detect the cell surface markers of CD90 and nestin. Reverse transcription-polymerase chain reaction (RT-PCR) was used to study the expression of the above-mentioned neurotrophic factors in the ADSCs. Moreover, adipogenic and chondrogenic differentiation of ADSCs were induced in-vitro.Results: The assessment of ADSCs identity and purity showed that 90% and 80% of the stem cells were positive for CD90 marker and nestin, respectively. According to RT-PCR results, the above-mentioned neurotrophic factors were expressed in these stem cells. Furthermore, a small number of cells were positive for cresyl violet staining. Conclusion: Adipose tissue contains a stem cell population that seems to be a good multipotential cell candidate for cell replacement therapy. Mesenchymal stem cell Neurotrophic factors Nestin 2011 12 01 322 330 http://feyz.kaums.ac.ir/article-1-1310-en.pdf
64-1324 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Isolation of biosurfactant-producing bacteria from the Caspian Sea and determination of their biosurfactant activity Aazam Safari azamsafary@yahoo.com Mostafa Akbarzadeh-Khayavi Mohamad Roayaei-Ardakani Hosain Motamedi Background: Biosurfactants are unique amphipathic molecules with extensive application in removing organic and metal contaminants. The purpose of this study was to isolate the biosurfactant-producing bacteria and characterize the surface-active properties of the metabolites produced.Materials and Methods: This study was conducted in three Caspian Sea coastal regions in Babolsar during 2007-8. In primary screening, hemolytic and emulsifying activities were performed on blood agar plates and in culture medium, respectively and then the reduction in the surface tension, as a biosurfactant-producing index, was determined quantitatively by captive drop cell instrument. The isolated strain was also investigated for its ability to use different hydrocarbon pollutants using the surface tension measurement.Results: One out of 10 different strains exhibited high ability to produce biosurfactant. This strain called Caspian petroleum A1 (CPA1). Biochemical tests showed that CPA1 classified in aerobic gram-negative cocci, neisseriaceae family and acinetobacter genus. CPA1 utilized crude oil and gasoline, as carbon and energy sources, to reduce the surface tension of culture medium from 71 to 42 and 39 mN/m. Conclusion: CPA1, as a biosurfactant-producer, was isolated and identified based on potential for biodegradation of hydrocarbon pollutants (e.g. crude oil, gasoline, anthracen and naphthalene). Isolation Biosurfactant Caspian Sea Surface-tension 2011 12 01 331 337 http://feyz.kaums.ac.ir/article-1-1324-en.pdf
64-1325 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Evaluating the sensitivity and specificity of total and free sialic acid levels for the diagnosis of bladder cancer and its relation to the stage and grade of tumor malignancy Shima Habibi Mahmood Djalali jalalimahmoud@hotmail.com Hasan Jamshidian Mohammad Reza Eshraghian Ali Akbar Saboor-Yaraghi Mahnaz Zareie Background: Bladder cancer is the second most common urological malignancy. Cystoscopy is the “gold standard” for the detection of bladder cancer, but is invasive and relatively expensive. This study aimed to investigate the sensitivity and specificity of serum levels of free and total sialic acids as tumor markers in the diagnosis of bladder cancer. Materials and Methods: In this study, the diagnostic value of blood samples collected from 58 patients with bladder cancer and 60 normal subjects were evaluated. The spectrophotometrical Aminoff's method was used for measuring serum levels of free and total sialic acids. After comparing the mean values for the mentioned parameters, ROC curve was used to calculate the sensitivity and specificity and other diagnostic values of markers. Results: The mean values for total sialic acid and free sialic acid were higher in cancer patients than in normal healthy controls (P<0.001). The sensitivity and specificity of total sialic acid at the cut-off point of 48.75 mg/dL were 91% and 82%, respectively and also the sensitivity and specificity of free sialic acid at the cut-off point of 0.708 mg/dL were 81% and 80%, respectively. Moreover, a positive correlation was seen between the serum levels of total, free sialic acids and stage or grade of the tumor. Conclusion: Our results revealed that the measurement of serum levels of these parameters using some simple, non-invasive, inexpensive, and reproducible tests can diagnose the bladder cancer and provide important clinical findings on the extent of the malignancy and also reduce the number of cyctoscopies. Urinary bladder cancer Sialic acid Tumor markers 2011 12 01 338 344 http://feyz.kaums.ac.ir/article-1-1325-en.pdf
64-1283 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Correlation between serum adiponectin level and blood glucose concentration in adult asthmatic patients Mojtaba Eizadi Farzad Nazem farzadnazem2@gmail.com Laleh Behboodi Davood Khorshidi Background: It has been hypothesized that obesity and disturbance in glucose metabolism can play an important role in the development of asthma. There is accumulating evidence in the literature that obesity can increase both the incidence and severity of asthma. Therefore, this study was conducted to determine the relationship between adiponectin, an anti-inflammatory cytokine, and blood glucose levels in overweight and obese adult patients with asthma. Materials and Methods: Forty-fine obese or overweight men (age 38-50 years) with mild-to-moderate asthma referred to Saveh health centers participated in this study. Fasting blood glucose, insulin, and adiponectin levels were measured. The homeostasis model assessment (HOMA) was applied to evaluate beta-cell function using fasting glucose and insulin levels. Data were analyzed using Pearson correlation coefficient.Results: The results of this study showed that there was a significant relationship between the serum adiponectin and FEV1/FVC, FEV1 and FVC in asthma patients. In addition, serum adiponectin level was positively correlated with insulin and beta-cell function, but negatively with fasting glucose level. Conclusion: According to the results, there is a negative correlation between serum adiponectin levels and blood glucose concentration in adult asthmatic patients. Furthermore, our findings showed that the reduction of systemic adiponectin level influences blood glucose concentration via insulin level and beta-cell function. Beta-cells Adiponectin Asthma Blood glucose 2011 12 01 345 351 http://feyz.kaums.ac.ir/article-1-1283-en.pdf
64-1323 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Relationship between mothers\' and daughters\' self-esteem Khadijeh Sharifi Negin Masoudi-Alavi Zahra Tagharrobi Zahra Sooki sooki812000@yahoo.com Fatemeh Sadat Asgarian Hosain Akbari Background: Adolescence is one of the most critical stages of human development. Low self-esteem is one of the problems that most adolescents often face with. Moreover, low self-esteem can cause other psychological disorders (e.g. anxiety, depression and drug abuse). Therefore, this study aimed to investigate the relationship between mothers' and daughters' self-esteem. Materials and Methods: In this cross-sectional descriptive study, 474 students were randomly selected among the Kashan's high schools during 2009-10. They were divided into three equal groups (low, average and high self-esteem) who met the inclusion criteria (ages 13-19, living with biological parents and without experiencing severe stress over the last year). Izink standard test and a researcher-made questionnaire were also used to assess both the mothers' and daughters' self-esteem scores less than 14 were considered as low self-esteem.Results: There was a significant relationship between mothers' and daughters' self-esteem (OR= 3.24, CI= 2.1-4.85, r=0.416). Seventy-six percent of mothers with low self-esteem had also daughters with low self-esteem. Moreover, while no significant relation was seen between the student's self-esteem and age, education level, birth order and number of brothers and sisters, but there was a significant relationship between the student's self-esteem and intimacy with mother, number of close friends, the average school scores in last year, extracurricular activities, feeling of success, popularity among friends and satisfaction with height and weight. Conclusion: Our study showed a positive correlation between mothers' and daughters' self-esteem. Self-esteem Self-confidence Self-efficacy 2011 12 01 352 358 http://feyz.kaums.ac.ir/article-1-1323-en.pdf
64-1313 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 A study on the variations of temperature, moisture, pH and carbon to nitrogen ratio in producing compost by stack method Rohollah Dehghani Esmaeel Charkhloo echarkhloo@yahoo.com Gholam Reza Mostafaii Mohammad Ali Asadi Sayyed Gholam Abbas Mousavi Mahmood Saffari Mohammad Pourbabaei Background: Considering the importance of chemical and physical parameters such as temperature, moisture, pH and carbon to nitrogen (C:N) ratio in producing compost, the purpose of this study was aimed to evaluate these parameters in producing compost by stack method. Materials and Methods: This descriptive study was carried out on municipal solid waste generated in Kashan during a 63-day period from Oct 3 to Dec 4, 2010. Compost samples were taken from the top one-third, the center and also the bottom of the compost pile and mixed the compost pile was aerated (if necessary). Thereafter, samples were analyzed for carbon and nitrogen content using Fourti method.Results: The initial temperature of the compost pile was 38°C and then increased to 65°C at the 9th day, and reached to 26°C at the last day of composting. The moisture at the beginning of the process was 67.5%, increased to 73% at the 5th day and decreased to 38% at the last day. The initial pH of the compost was 5.5, increased during the compost process, and reached an optimal value of 7.7 at the end of the process. The C:N ratio at the beginning of the process was 35:1 and in mature compost decreased to 12.5:1. Conclusion: Presence of actinomycetes and the dark-brown color of the prepared compost on the 63rd day of composting indicate that the compost meets the required standards. Consequently, the implementation of this method is suitable for tropical cities like Kashan. Compost Temperature Moisture pH Carbon to nitrogen ratio 2011 12 01 359 365 http://feyz.kaums.ac.ir/article-1-1313-en.pdf
64-1311 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Job stress among the nursing staff of Kashan hospitals Abbas Bahrami bahrami_a@kaums.ac.ir Hosain Akbari Sayyed Gholam Abbas Mousavi Mitra Hannani Yadolah Ramezani Background: Job stress, the most important factor in reducing organizational productivity and the cause of psychosomatic disorders, today is more prevalent among the healthcare staff. Therefore, the aim of the present study was to assess the level of job stress among the nursing staff of Kashan hospitals during 2009.Materials and Methods: This descriptive cross-sectional study was performed on 190 nurses of Kashan hospitals using the Osipow questionnaire consisted of two parts: demographic data and six stress-inducing work roles (role overload, role insufficiency, role ambiguity, role boundary, responsibility and physical environment). In addition, job stress was divided into four (subnormal, normal, moderate and severe) levels. Results: Results indicated that the 95.3% of nursing staff were found to have a normal level of job stress. No significant relationship was seen between the job stress and gender however, there was a significant relation between the role insufficiency, role boundary, responsibility and physical environment and gender. Moreover, no significant relationship was found between the job stress and some factors (e.g. age, education, marital status, income and type of hospital). The most frequent job stressors among the men and women were responsibility (90.2%) and role ambiguity (40.9%), respectively.Conclusion: Role ambiguity, responsibility and workload are the major sources of stress among the nursing staff. Job stress Hospital Osipow job stress questionnaire Nurse 2011 12 01 366 373 http://feyz.kaums.ac.ir/article-1-1311-en.pdf
64-1284 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Epidemiology of attempted suicide in Kashan during 2003-8 Sayyed Alireza Moravveji Hamidreza Saberi hamisa2002@yahoo.com Godarz Akasheh Afshin Ahmadvand Sima Kiani-Pour Background: Suicide is a major public health problem in developing countries which depending on geographical area, several factors have been associated with its prevalence and incidence. This study was conducted to evaluate the prevalence of attempted suicide and its related factors in Kashan during 2003-8. Materials and Methods: This cross-sectional study was performed on all suicide attempters referred to Kashan health centers during 2003-8. Patient's demographic information, manner, outcome and a previous history of suicide attempts were recorded on a questionnaire by interviewing patients or their families. Results: There were 2867 suicide cases during the study period. Most of them were in age range of 25-35 years. Fifty-nine percent of patients were female and 56% married. Drug abuse was the most common method of suicide (79%). So, an overall attempted suicide rate was 119 per 100000 people in Kashan during 2003-8 and there were only 29 cases (1.1%) of successful suicide. Conclusion: Although the rate of attempted suicide are high in this city, the rate for successful suicide is very low. Therefore, this problem and its related factors need to be considered by health managers. Attempted suicide Suicide Drug abuse 2011 12 01 374 381 http://feyz.kaums.ac.ir/article-1-1284-en.pdf
64-1285 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Evaluating the corrosive and scale-forming indices of water in the villages under the coverage of Kashan rural water and wastewater company during 2007-9 Davarhkah Rabbani d-rabbani@Kaums.ac.ir Mohammad Bagher Miranzadeh Amin Paravar Background: Kashan rural water and wastewater company (KRWWC) in Iran is facing a multitude of problems including some potential health risks associated with pipe corrosion byproducts, their early deterioration, the occasional interruption of the water supplies and also huge operation costs. Therefore, this study aimed to evaluate the corrosive and scale-forming properties of water in Kashan villages.Materials and Methods: This descriptive study was carried out on 151 water samples taken from 39 rural water supplies in 4 stages during 2007-9. All samples were analyzed for total hardness, calcium, alkalinity, total dissolved solids (TDS), bicarbonate, temperature and pH according to the last edition of the Standard Methods Book and then Ryznar, Langelier and Puckorius indices were calculated. Data were analyzed using Fisher's exact test and Paired t-test followed by Bonferroni correction.Results: According to Ryznar, Puckorius and Langelier indices, 95%, 97% and 74% of the water supplies in all seasons were corrosive, respectively. Moreover, according to the three above-mentioned indices, 18 villages (46.15%) under the coverage of Kashan rural water and wastewater company have always had corrosive water and there was also no significant difference in water quality between the seasons.Conclusion: Results showed that most water supplies are corrosive and a few of them are scale-forming. Hence, application of suitable plumbing utensils, turn on/off bypass pumps and valves and if necessary, appropriate water treatment are recommended. Water Corrosion Water supply 2011 12 01 382 388 http://feyz.kaums.ac.ir/article-1-1285-en.pdf
64-1328 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Serum ferritin level in febrile children with and without seizures Ahmad Talebian Somayeh Andalib dr_andalib82@yahoo.com Sayyed Alireza Moravveji Zarichehr Vakili Background: Although febrile seizure is the most common cause of convulsion in childhood and strongly age-dependent, its incidence is rare before 9 months and after 5 years. Moreover, iron deficiency in these ages may have a detrimental effect on neurological and intellectual functioning. This study was designed to determine the serum ferritin level in febrile children with and without seizures. Materials and Methods: This case-control study was performed on 80 children (6 months to 5 years) referred to Kashan Shahid Beheshti hospital from January until June 2010.They were divided into two equal case and control groups (children with febrile seizures and febrile children without seizure, respectively). Children with the CNS disorder, developmental delay, renal failure, and shigellotic gastroenteritis were excluded. Ferritin, Hb, MCV and MCH values between the two groups were compared. Results: The mean serum feritin levels were 97.6±90.6 ng/ml for cases and 109.2±106.2 ng/ml for controls (P=0.351).The mean corpuscular hemoglobin was 11.17±0.881 g/dl in the case group and 11.04±0.963 g/dl in the control one (P=0.534). Moreover, the mean MCV in the febrile seizure and fever groups were 73.71±4.16 fl and 71.86±4.42 fl, respectively (P=0.049). Also, the mean MCH in the febrile seizure and fever groups were 24.80±1.64 pg and 23.83±2.16 pg, respectively (P=0.033). Conclusion: No relationship between the serum ferritin level and febrile seizure is seen in both groups. Febrile seizure Ferritin Iron deficiency anemia Children 2011 12 01 389 393 http://feyz.kaums.ac.ir/article-1-1328-en.pdf
64-1318 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 A case report of angioimmunoblastic T-cell lymphoma in a 16-year-old patient Majid Ehsani mehsani 20032003@ yahoo.com Alireza Hosseini Background: Angioimmunoblastic T-cell lymphoma (AITL) which is recognized in the current world health organization classification as a peripheral T-cell lymphoma of the non-hodgkin lymphomas, comprises about 1% of all lymphomas. The average age at the time of diagnosis of AITL is about 65 years and it is rarely seen in patients under 18 years. Case report: A 16-year-old boy suffering from fever, weakness, paleness, and axillary lymphadenopathy was referred to Kashan Shahid Beheshti hospital. Laboratory tests showed pancytopenia and elevated LDH. Splenomegaly and normal liver size were also reported by sonographist. Bone marrow aspiration was normal and reactive follicular hyperplasia was reported on the first biopsy of axillary lymph node, but with continuing fever and pancytopenia biopsy of the axillary lymph node was performed again and this time AITL was also reported using the pathological and immunohistochemical evaluation. Conclusion: AITL, a rare lymphoma under 18 years old, typically manifested by lymphadenopathy, splenomegaly, elevated serum LDH and systemic B-symptoms. One of the most common differential diagnoses of AITL is reactive t-cell infiltrative processes which in some cases pathologists may have difficulty distinguishing between them. The diagnosis was confirmed by immunophenotyping and pathology of the axillary lymph nodes. Immunoblastic lymphadenopathy Reactive lymphocytic infiltration Non-hodgkin lymphoma 2011 12 01 394 397 http://feyz.kaums.ac.ir/article-1-1318-en.pdf
64-1286 2024-03-29 10.1002
Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2011 15 4 Naderinasabm@mums.ac.ir 2011 12 01 398 399 http://feyz.kaums.ac.ir/article-1-1286-en.pdf