2024-03-28T11:44:43+03:30 http://feyz.kaums.ac.ir/browse.php?mag_id=21&slc_lang=fa&sid=1
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Effect of hydroacoholic Zizyphus spina christi leaf extract on perfused frog heart contractility and frequency Mohamamd Kazem Gharib Naseri Background: Zizyphus spina Christi is a native plant of Iran. In traditional medicine, it is mainly used to wash hair. The present study was conducted to determine the effect of hydroacoholic Zizyphus spina christi leaf extract on perfused frog heart contractility and frequency.Materials and Methods: It was an experimental study. The frog heart was cannulated through vena cava and then perfused with standard ringer solution. Having completed the oxygenation and feeding, the ringer solution was extracted through another cannulated tube via left branch of aorta. After recovery, the extract was added to reservoir to achieve the final concentrations of 0.625, 1.25, 2.5, 5, 10, and 20 mg/ml. Percentage changes of contractility and heart rates were recorded before and after adding the extract. Ringer solution, 20-22 degrees centigrade and PH=8.4 was kept on pressure of 5.5cmH2O as a constant venous pressure. For comparison, paired t-test and ANOVA were used.Results: Twenty-five frogs have been studied. The extract could dose-dependently reduce the contractility and heart rate (p<0.0001). Concentration of 20 mg/ml in most cases caused cardiac arrest but contractility was restored by fresh Ringer's solution. Cardiac arrest was not affected by atrial electrical stimulation.Conclusion: It seems as if the extract contains materials that disturb the usage of Ca2+ during contraction mechanism. Zizyphus spina Christi Frog heart contractility heart rate 2003 7 01 1 7 http://feyz.kaums.ac.ir/article-1-253-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 A comparison of oral clindamycin and oral metronidazole in the treatment of bacterial vaginosis Sayed Ziyaaddi Moosavi Roksana Behrouzi Background: Bacterial vaginosis is one of the most common infection disorders affecting women. Several types of antibiotics have been used to treat this condition, although metronidazole was found to be the most effective one, none was completely successful in either cure or prevention. The purpose of this study was to compare the efficacy and safety of oral clindamycin and oral metronidazole in the treatment of bacterial vaginosis.Material and methods : Sixty women aged 16 years or older in whom bacterial vaginosis was diagnosed by standard criteria such as Amsel’s and gram’s stain criteria were enrolled in a randomized, double-blind study to receive either oral clindamycin (300mg twice daily for 7 days) or oral metronidazole (500mg twice daily for 7 days). Women with coexisting vulvovaginal candidiasis or vaginal trichomoniasis were excluded. Tests were repeated at 7th and 14th day following the therapy. Vaginal symptoms, complications, and drug side effects were all recorded. Result : We have not found any statistically significant difference in cure rates for oral clindamycin (93.3%) and oral metronidazole (86.6%). Adverse reactions were mild in both groups. Four patients who have received clindamycin developed non-bloody diarrhea and 4 patients who were given metronidazole developed symptomatic candida vaginosis. Conclusion : Clindamycin may be a safe and effective alternative to metronidazole to treat women with bacterial vaginosis. Bacterial vaginosis Metronidazole Clindamycin 2003 7 01 8 14 http://feyz.kaums.ac.ir/article-1-260-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Genetic polymorphism in patients with colon cancer Mandana Yadollahi Mostafa Saadat Iraj Saadat Background : Discovering the etiology of diseases especially cancers are research priority. There are controversies around the role of absence of GSTM1 and increased risk of development of several malignancies. Thus, the present study was conducted to determine the association between its genotypes and colon cancer in Namazi hospital in Shiraz. Materials and methods: For this case-control study, the polymorphism of GSTM1 was determined using PCR technique in 38 patients with colon cancer and 76 control subjects. Chi-square and odd’s ratio were used for data analysis. Results : The frequency of null genotype was 32.9% and 50% in controls and cases, respectively (p<0.05). There exists a statistically significant association between null genotype and colon cancer among individuals older than 59 years old (p<0.02). Conclusion : There is a close association between GSTM1 null genotype, especially in older population, and development of colon cancer. Colon cancer PCR GSTM1 2003 7 01 15 20 http://feyz.kaums.ac.ir/article-1-259-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Trichomoniasis in parturients referring to Shabihkhani hospital in Kashan, 2001-02 Sima Rasti rasti_s@kaums.ac.ir Afsane Taghriri Mitra Behrashi Background : Trichomoniasis was reported to have great influence on pregnancy and fetus health. Since the true epidemiological profile of trichomoniasis profile is not obvious in Kashan, the present study was performed on parturients referring to Shabihkhani hospital, between 2001 and 2002. Materials and methods : For this descriptive study, initial data were gathered via history, clinical examination, laboratory studies, and culturing. Results: Of 450 parturients, 2 (0.44%) were revealed to be infected by trichomoniasis. These two had preterm delivery with low birth weight neonates. They both have watery discharge with vaginitis. Conclusion : Trichomoniasis is not a common infection in Kashan. It is associated with preterm delivery, PROM, and LBW neonate. Meanwhile, clinical picture and laboratory findings can not provide adequate clues for definite diagnosis. Trichomoniasis Preterm delivery clinical manifestation 2003 7 01 21 25 http://feyz.kaums.ac.ir/article-1-261-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Breast feeding and its related factors in Zahedan Mahmoud Imani Mahdi Mohammadi Fateme Rakhshani Sousan Shafie Background : Breast-feeding during the first 6 months of life has great impact on child health especially in developing countries. The duration of such important period depends on sociocultural status of the society, thus, its related factors should be determined. The present study was carried out to determine the duration of breast-feeding and its related factors in Zahedan in 2000-01. Materials and methods : For this cross sectional study 253 mothers who have child aged 6-24 months and referred to health centers were randomly selected. Initial data were gathered through a face-to-face interview, then, mothers’ performance regarding breast-feeding during the first 6 months was determined. Role of prenatal education and other related factors was assessed. Results : Results have revealed that 46.3% of mothers were illiterate, 74.7% aged 30 and less, and 7.9% were employed. There were 53.4% girls and 46.6% boys. Of 97.6% started breast-feeding, 44.7% continued till the 6th month. There was a statistically significant positive association between prenatal education and breast-feeding, whereas a negative association was noted between maternal disease during the first 6 months and breast-feeding. Conclusion : Promoting prenatal education, paying further attention to old mothers and maternal awareness about diseases that are not contraindicated for breast-feeding could improve breast-feeding that in turn may reduce infant mortality rate. Breast-feeding Infant Nutrition 2003 7 01 26 33 http://feyz.kaums.ac.ir/article-1-258-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Success rate of first probing in children under 5 years Davoud Aghadoost aghadoost_d@kaums.ac.ir Mohammad Zare Background : With respect to the relatively high prevalence of nasolacrimal duct obstruction and controversies around the success rate, optimum time of probing, and follow up, the present study was conducted in 6-60 month old children to determine the success rate. Materials and methods : This clinical trial was performed on 56patients (71 eyes). All patients underwent nasolacrimal duct-probing and irrigation under general anesthesia, then followed for 6 months. Cessation in lacrimation and discharge was considered as a success in probing. Chi-square was used for data analysis. Results : The overall success rate of probing was 78.6%. There exists an association between child age and success rate (p<0.05). During the first 3 months, 91% had complete improvement. Conclusion : Success rate of nasolacrimal duct-probing is excellent in patients aged 6-12 months. This success is decreased as age increased. Repeated probing is suggested to be postponed to at least 3-6 months later the first attempts. Probing nasolacrimal duct obstruction 2003 7 01 34 37 http://feyz.kaums.ac.ir/article-1-249-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Effects of short wave radio frequency of electromagnetic fields on peripheral motor nerve latency Zahra Zabolizadeh Bahram Bolouri Hasan Ashayeri Background : Different regions of radio frequency spectrum of electromagnetic waves have various physiological effects on biological systems. Since short wave is routinely used as a therapeutic means to elevate deep body temperature, it seemed worthwhile to investigate the none thermal effects of this frequency band. Materials and methods : For this experimental study, 42 normal individuals aged 20-30 years were selected. The nerve latency was measured at the left wrist before and after 10 minutes exposure to the lowest field intensity to assure minimal thermal effect. Paired t-test was used for data analysis. Results : Small variation has minimal effect on latency values. 95% of the subjects demonstrated latency change due to the field. The 8.56% difference between the latencies measured before and after applying the field was statistically significant. The difference has lasted for 11 minutes. Conclusion: Short wave radio frequency does influence on nerve latency. Further studies are strongly recommended. Radio frequency Electromagnetic wave Latency Median nerve 2003 7 01 38 42 http://feyz.kaums.ac.ir/article-1-263-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Behavioral habits and ischemic heart disease in Kashan, 1995 Mohsen Taghaddosi taghadosi_m@kaums.ac.ir Gholam Reza Vali Background: Cardiovascular diseases are among the most common cause of death in Iran. Changes in life styles and habits may be accompanied by less mortality and morbidity due to cardiovascular diseases. The present study was performed to determine the behavioral habits in ischemic heart disease in patients hospitalized in Shaheed Beheshti hospital in Kashan.Materials and methods : For this case-control study, patients admitted in CCU were considered as case and those noncardiac disease admitted in surgery or internal medicine wards were referred to as control. Groups were matched according to the sex and age. A questionnaire including sex, age, occupation, marital status, education level, smoking habit, daily activity, and OCP usage was completed for all participants. Results : 400 patients were equally distributed in two groups of case and control. In the case group70 patients (35%) aged 66 or higher, 121 (60.7%) were males, 87% were married, 62% were illiterate, an 35.5% were housewife. 39 (19.5%) have frequently had salty meals. 57 (28.5%) used animal-based oils. 132 (66%) used tea or coffee frequently. 119 (59%) reported mild-moderate physical activity. 53 (26.5%) were smoker, among these, 53% smoked for 10-20 years and 30% smoked for more than 20 years. 18 (23%) were OCP users, among these, 34% used these drugs for more than 5 years. Conclusion : A large proportion of our studied patients was married males aged greater 66 years. Further educational programs regarding low salt and fatty food intake as well as regular physical activity, cessation of smoking are strongly suggested. Ischemic heart disease Behavioral habits 2003 7 01 43 49 http://feyz.kaums.ac.ir/article-1-262-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Clinical features of Burger disease in patients referring to Taleghani hospital, 2000-01 Mohamamd Taghi Salehian Hossein Parsa Naser Valaie Background: Burger disease is a relative common problem. The present study was conducted to determine the clinical features of Burger disease in patients referring to Taleghani hospital between 2000 and 2001. Materials and Methods: It was a descriptive study. Diagnosis was made according to the clinical manifestations and angiographic studies. Finally, clinical features, and other demographic characteristics were recorded and analyzed using descriptive statistics.Results: There was 42 patients with Burger disease, all of whom were male with the mean (±SD) age of 35.9±2 years. All of the subjects were smokers. 71% were addicted and 54.8% have been smoking for 10-20 years. 77.3% had low educational level and 69% were belonged to low-health status class. Pain on rest (81%), ischemic ulcer, claudication, gangrene, migrating thrombophlebitis, and upper limb pain were the most common symptoms. Conclusion: Our study revealed different clinical profile as compared to western societies. Low socioeconomic status is associated with greater risk of Burger disease. Further studies are highly suggested. Burger Obliterans thrombophlebitis 2003 7 01 50 54 http://feyz.kaums.ac.ir/article-1-254-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Surveying the risk factors for first febrile convulsion Ahmad Talebia talebian_a@kaums.ac.ir Ali Honarpisheh Saeid Mohajeri Mohsen Taghddosi Background : Febrile convulsion is a common problem that leads to a large number of hospitalizations. The present study was conducted to determine the risk factors for febrile convulsion in infants hospitalized in Shahid Beheshti hospital in Kshan in 2001. Materials and Methods : For this case-control study 180 children were selected. Children were distributed in two groups of febrile convulsion (60 children) and febrile children without convulsion (120 children), then risk factors were studied between the groups. Initial data including age, sex, familial history of febrile convulsion, epilepsy, developmental delay, and prenatal problems were all collected and analyzed using Fisher's exact test. Results : The study population included 108 (60%) boys and 72 (40%) girls, aged between 6 months and 5 years. Febrile convulsion was more frequent among children under 3 years old (78%) and boys (60%) as well. The most common risk factors were familial history of febrile convulsion (55%), prenatal problems (28%), familial history of epilepsy (10%), and developmental delay (5%). Conclusion : Children aged less than 3 years are at high risk to develop convulsion during their upper respiratory tract viral infection in case of a positive familial history of febrile convulsion. Thus, prophylaxis with diazepam is highly recommended in case of fever of ≥38 ْ C. Familial history of febrile convulsion, prenatal problems, familial history of epilepsy, and developmental delay are associated with greater risk of febrile convulsion. Febrile convulsion Infant 2003 7 01 55 58 http://feyz.kaums.ac.ir/article-1-257-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Prevalence of papilledema and its related factors in patients referring to Farabi hospital, Tehran, 1997-99 Sayed Abdorreza Tabasi Leila Ettefagh Background : Papilledema is relatively a common problem. The present study aimed to determine the prevalence of papilledema in a group of Iranian patients referring to a neuroophthalmology clinic in Tehran, between 1997 and 1999. Materials and methods : It was an existing data type study. Form medical files of patients, those who have diagnosed as papilledema were selected, then initial data including sex, age, clinical features, and accompanied findings were recorded. Results : Of 739 patients referring to Farabi hospital, 36 (4.87% CI=95%, 3.4-6.4%) had diagnosed as papilledema. Of these, 52.7% were females and 47.3% were males. The most common etiologies were tumors (36.1%) and pseudotumor cerebri (25%). Of 36 affected patients, 35 had bilateral papilledema and one had unilateral disease with optic nerve atrophy. Headache (55.5%) and transient blurred vision (41.6%) were other prevalent symptoms. Conclusion : Papilledema could be detected during ophthalmoscopy. With respect to its known complications, further studies are highly recommended. Papilledema diagnosis 2003 7 01 59 62 http://feyz.kaums.ac.ir/article-1-255-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Surveying patients with leukorrhea, bacterial causes and drug resistance Fariba BeghnamFar behnamfar_f@kaums.ac.ir Ahmad Khorshidi Khorshid Araghi Background : Leukorrhea is a common cause of physician's visit during the fertility period. Unfortunately, sufficient data regarding the microbial causes are lack and diagnosis is made based on macroscopic appearance. The present study was aimed to survey the bacterial causes of leucorrhea and drug resistance in Shabih Khani hospital in Kashan. Materials and Methods : 301 patients with leukorrhea had referred for this descriptive study. In case of any complaint regarding the excess vaginal discharge, sampling and culturing was performed. Then, drug resistance was conducted. Finally, data were analyzed. Results: 301 patients aged 25-30 years were studied. Frequent symptoms were itching (47.5%), pain and tenderness. Cultures were revealed to be negative in 61.1%. Of 38.9% positive cultures, enterococcus (12.6%), and mixed bacteria were the most common findings. 75% had claimed to have the vaginal discharge for months and 25% had received no treatment, among those who have been on therapy, local ointments were the most common therapeutic facility. Drug resistance has shown a different profile, where no simple drug could provide a high level of sensitivity. 37% of patients had negative paraclinical studies (physiologic leukorrhea). Conclusion : 30% had physiologic leukorrhea that did not require any further therapy. Bacterial leukorrhea is a common problem. We suggest antibiogram for all patients with leukorrhea. Leukorrhea Bacterial vaginosis Vaginitis 2003 7 01 63 70 http://feyz.kaums.ac.ir/article-1-251-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Prevalence of cutaneus leishmaniasis in Kashan, 1994-2000 Safar Ali Talari Zarichehr Vakili Saeid Moshtaghi Background: Due to augmented spread of cutaneus leishmaniasis in our country that impose great economic problems for the sufferers and also with respect to the lack of informative data regarding its status in Kashan, The present study was conducted in 1994-2000 to determine the prevalence of cutaneus leishmaniasis in patients referring to parasitology laboratories in Kashan.Material and methods : A descriptive study was carried on all referred patients to laboratories during a 7- year period, 1994-2000. Initial data including age, sex, occupation, place of resident, and number of lesions were all recorded. Suspected individuals were asked for samples and Leishman body was surveyed by a microscope following the gimsa staining. Results : The incidence rate of cutaneus Leishmaniasis was reported 50.2% in females and 49.2% in males. The highest prevalence rate (37.9%) was shown in 0-10 years old subjects. More than one active lesion was reported in 30.3% of individuals. Hands were more commonly affected (45.6%). Conclusion : With respect to the increased prevalence of cutaneus leishmaniasis in Kashan, health care observers should pay further attention on preventing the disease spread Cutaneous Lieshmaniasis Prevalence Kashan 2003 7 01 71 76 http://feyz.kaums.ac.ir/article-1-256-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Multiple pregnancy and its complication-induced hospitalization in Shaheed Beheshti and Shabihkhani hospitals, Kashan, 2000-01 Ziba Mosayebi mosaieby_z@kaums.ac.ir Amir Hossein Movahedian Sayed Bahman Mirtalaie Background : Considering the importance of multiple pregnancy and its influence on neonate’s mortality and morbidity and also with respect to the lack of informative data on its prevalence, the present study was conducted in Shaheed Beheshti and Shabihkhani hospitals in Kashan, 2000-01, to determine the role of early diagnosis and treatment. Materials and methods : During a one-year period, all multiple pregnancies were included. Initial data including gestational age, sex, maternal age, complication-induced hospitalization, birth weight, previous history of multiple pregnancy, mortality, and history of ovarian-stimulating drug consumption were all recorded in a questionnaire. Results : Of 10011 deliveries, 142 (1.4%) were twins, 8 (0.079%) were triplets, and 1 (0.009%) was quadruplets. Of these, 58 twins (40.8%), 5 triplets (62.5%) and 1 (100%) quadruplets were hospitalized. Prematurity was the most common complication in twins (84%). Mortality was reported in 15 twins (13.5%) and 3 triplets (21.4%). The most seasonal prevalence of twin pregnancy was winter (27.4%). Conclusion : Prematurity was more common as compared to western data. Prematurity and low birth weight are the most frequent cause of mortality, thus prevention of preterm delivery is highly recommended. Multiple pregnancy Twin Prematurity Mortality 2003 7 01 77 84 http://feyz.kaums.ac.ir/article-1-252-en.pdf
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Feyz Medical Sciences Journal Feyz 1029-7855 2008-9821 2003 7 2 Knowledge, attitude, and performance of women referring health care centers in Kashan towards breast cancer and its screening tests Masoume Abedzadeh abedzadeh@kaums.ac.ir Zohre Sadat Farzane Saberi Background : Breast cancer has been increased rapidly during the recent decades, however, self examination and clinical evaluation have been revealed to be effective for early diagnosis. The present study was conducted to determine knowledge, attitude, and performance of women referring health care centers in Kashan towards breast cancer and its screening tests. Materials and methods : For this descriptive study 400 women were selected through a cluster sampling. Then, initial data such as age, marital status, educational level, occupation, familial history of breast cancer, self examination training, and other breast related diseases were recorded meanwhile knowledge and attitude were considered and performance was surveyed by direct observation. Results : The mean ( ± SD) age of women was 29.7 ±7.9. The vast majority of participants were housewives, married and had under diploma education. Poor knowledge of breast cancer was revealed in 43%.,however, negative attitude and poor performance were observed in 5.5% and 65.3% of women, respectively. Better performance is achieved by increment in knowledge. Conclusion : Most of the women had poor knowledge and performance regarding the breast cancer and its screening test. With respect to the importance and efficacy of self-examination in early diagnosis we highly suggest educational programs to promote knowledge, attitude, and performance towards the breast cancer. Knowledge attitude performance breath cancer 2003 7 01 85 92 http://feyz.kaums.ac.ir/article-1-250-en.pdf