TY - JOUR T1 - Relationship between some immunological indexes and maximal oxygen pulse in active girls: effect of a bout of intense aerobic physical activity TT - بررسی رابطه بین برخی از شاخص های سیستم ایمنی با حداکثر نبض اکسیژن در دختران فعال: اثر یک وهله فعالیت شدید هوازی JF - KAUMS JO - KAUMS VL - 20 IS - 1 UR - http://feyz.kaums.ac.ir/article-1-2968-en.html Y1 - 2016 SP - 25 EP - 32 KW - Active girls KW - Exercise KW - T CD4+ KW - CD8+ KW - Natural killer cell KW - Maximal oxygen pulse N2 - Background: The aim of this study was to determine the relationship between T lymphocytes (CD4+, CD8+), NK (CD56+), CD4+/CD8+ ratio and maximal oxygen pulse among the active girls in response to an intense aerobic physical activity. Materials and Methods: This semi-experimental study was conducted on 20-25 years old active women. To estimate maximal oxygen pulse and immune response parameters, GXT treadmill test was performed. In order to evaluate the immune system response to intense physical activity, blood samples were obtained at 3 times (before, immediately after and 2 hours after the exercise). Results: The T-CD4+cells and CD4+/CD8+ rations were significantly decreased after an intense aerobic physical activity (P<0.05). However, the levels of CD8+ and CD56+ cells were significantly increased after the same physical activity. The results also showed a significant positive relationship between maximal oxygen pulse and CD8+, CD56+ cells level (r=0.699, P<0.001), (r=0.49, P≤0.009). In addition, there was a significant negative relationship between maximal oxygen pulse and CD4+ (r=-0.645, P≤0.008), CD4+/CD8+ T-cell ratios (r= - 0.539, P<0.002). Conclusion: The findings of this research showed that in active women the maximal oxygen pulse, as an indicator of the efficiency of the cardiovascular system, has strong relationship with some immune system parameters. M3 ER -