AU - Ghirvani, Zahra AU - Pour Gholomi, Mohammad TI - Effect of GABA-A receptor through peripheral mechanisms to regulation blood Glucose concentration in mice PT - JOURNAL ARTICLE TA - KAUMS JN - KAUMS VO - 4 VI - 4 IP - 4 4099 - http://feyz.kaums.ac.ir/article-1-411-en.html 4100 - http://feyz.kaums.ac.ir/article-1-411-en.PDF SO - KAUMS 4 ABĀ  - History and Objectives: The regulation of glucose concentration in blood is one of the complex phenomenons, which is effected by several hormonal and neuronal systems. In addition to hormones, neurotransmitters like GABA also play a role in the homeostasis of blood glucose. Materials and Methods: In this experimental study male albino mice weighting 20-25 grams were used. The effect of GABA agonist and antagonist on the glucose concentration was determined. The effect of various doses of drug on blood glucose was assessed. T-student test and one way variance analysis was carried out on two groups. Results: The injection of bicucullin and picrotoxin induce a significant increase glucose concentration in two groups (P CP - IRAN IN - Department of Physiology, Birjand University of Medical Scienecs, Birjand, Iran LG - eng PB - KAUMS PG - 27 PT - Research YR - 2001